2020 - 2022 Interaction between triple negative breast cancer and bone marrow stromal cells promote bone metastasis.
2017 - 2020 Zeb-1 promotes epithelial-mesenchymal transition and metastasis in breast cancer
2015 - 2018 Identification of imatinib resistance factor and the therapeutic strategies to overcome resistance in chronic myeloid leukemia
Papers (60)：
Tomoya Takeda, Masanobu Tsubaki, Shuji Genno, Kana Tomita, Shozo Nishida. RANK/RANKL axis promotes migration, invasion, and metastasis of osteosarcoma via activating NF-κB pathway. Experimental cell research. 2024. 436. 2. 113978-113978
Tomoya Takeda, Masanobu Tsubaki, Shuji Genno, Kenta Tokunaga, Remi Tanaka, Shozo Nishida. HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple-negative breast cancer metastasis via the inhibition of CXCR4 expression. International journal of molecular medicine. 2023. 52. 3
Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Kana Kishimoto, Honoka Takefuji, Yuzuki Taniwaki, Misa Ueda, Tadafumi Hoshida, Kazufumi Tanabe, Shozo Nishida. Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy. Cancer cell international. 2023. 23. 1. 73-73
Masanobu Tsubaki, Tomoya Takeda, Yuuichi Koumoto, Takehiro Usami, Takuya Matsuda, Shiori Seki, Kazuko Sakai, Kazuto Nishio, Shozo Nishida. Activation of ERK1/2 by MOS and TPL2 leads to dasatinib resistance in chronic myeloid leukaemia cells. Cell proliferation. 2023. 56. 6. e13420
Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Kana Kishimoto, Remi Tanaka, Katsumasa Tsurushima, Toshihiko Ishizaka, Shozo Nishida. Bim downregulation by activation of NF-κB p65, Akt, and ERK1/2 is associated with adriamycin and dexamethasone resistance in multiple myeloma cells. Clinical and experimental medicine. 2022
木村智裕, 椿正寛, 武田朋也, 松田拓弥, 山本裕太, 森井悠介, 森井悠介, 西田升三. Overexpression of Serum/Glucocorticoid Regulated Kinase 1 is involved with proteasome inhibitor resistance in multiple myeloma. 日本がん分子標的治療学会学術集会プログラム・抄録集. 2021. 25th
岸本佳奈, 椿正寛, 武田朋也, 松田拓弥, 山本裕太, 森井悠介, 森井悠介, 西田升三. Myeloma cells-secreted HGF accelerate the bone destruction via increased RANKL expression in bone marrow stromal cells and osteoblasts. 日本がん分子標的治療学会学術集会プログラム・抄録集. 2021. 25th
椿正寛, 武田朋也, 松田拓弥, 山本裕太, 木村智裕, 森井悠介, 森井悠介, 西田升三. Rhosin inhibits tumor metastasis via suppression of Rho/YAP pathway. 日本がん分子標的治療学会学術集会プログラム・抄録集. 2021. 25th
Mechanism of tamoxifen acquired resistance via EMT induction by EGFR activation in breast cancer cells
(The 82th Annual Meeting of the Japanese Cancer Association 2023)
AT9283 exhibits antiproliferative effect on BCR-ABL TKI sensitive and resistant CML cells by inhibition of Aurora.
(The 81th Annual Meeting of the Japanese Cancer Association 2022)
AT9283 suppresses proliferation in tyrosine kinase inhibitor sensitive and resistant chronic myeloid leukemia cells by inhibition of Aurora A and Aurora B.
(The 5rd International Cancer Research Symposium of Training Plan for Oncology Professionals 2022)
