Kitaoka Shiho

キタオカシホ | Kitaoka Shiho

Affiliation and department：
Job title： Professor and Chairman
Other affiliations (2)：

Homepage URL (1)： http://kaken.nii.ac.jp/d/r/00545246.ja.html

Research field (2)： Pharmacology , Neuroscience - general

Research keywords (10)： stress , 神経科学 , 脳・神経 , inflammation , microglia , 血球 , 鉄代謝 , 脳神経疾患 , iPS細胞 , ALS

Research theme for competitive and other funds (7)：

2021 - 2024 Elucidation of molecular basis underlying stress-induced iron dysregulation and its behavioral relevence
2019 - 2021 Elucidating whether and how hematocytes hamper willpower
2017 - 2020 脳内炎症を惹起する神経細胞由来分子の同定
2016 - 2019 精神疾患に関わるストレスによる前頭前皮質の機能形態変化のメカニズムと意義の解明
2012 - 2016 Elucidation of molecular and neural-circuit mechanisms of stress susceptibility related to mental illnesses

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Papers (39)：

Io Horikawa, Hirotaka Nagai, Masayuki Taniguchi, Guowei Chen, Masakazu Shinohara, Tomohide Suzuki, Shinichi Ishii, Yoshio Katayama, Shiho Kitaoka, Tomoyuki Furuyashiki. Chronic stress alters lipid mediator profiles associated with immune-related gene expressions and cell compositions in mouse bone marrow and spleen. Journal of pharmacological sciences. 2024. 154. 4. 279-293
Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishida. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in Neuroscience. 2023. 17
Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Shinya H. Kimura, Yasuhiko Yamamoto, Masahiro Nishibori, Tomoyuki Furuyashiki. Repeated Social Defeat Stress Induces HMGB1 Nuclear Export in Prefrontal Neurons, Leading to Social Avoidance in Mice. Cells. 2023. 12. 13. 1789-1789
Satoshi Akiyama, Hirotaka Nagai, Shota Oike, Io Horikawa, Masakazu Shinohara, Yabin Lu, Takashi Futamura, Ryota Shinohara, Shiho Kitaoka, Tomoyuki Furuyashiki. Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice. Scientific Reports. 2022. 12. 1
Risa Sakate, Masahiro Nishiyama, Yu Fukuda, Shiho Kitaoka, Tomoyuki Furuyashiki. The transcription factor Hhex regulates inflammation-related genes in microglia. Journal of pharmacological sciences. 2022. 149. 3. 166-171

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MISC (49)：

Ayaka Tomohiro, Shinya Ukeshima, Shiho Kitaoka, Xiang Nie, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Masahiro Nishibori, Tomoyuki Furuyashiki. Roles and Mechanisms of Neuroinflammation in Stress and Depression. NEUROPSYCHOPHARMACOLOGY. 2019. 44. SUPPL 1. 120-121
Furuyashiki Tomoyuki, Akiyama S, Kitaoka Shiho. Roles of multiple lipid mediators in stress and depression. Int Immunol. 2019. 31. 9. 579-587
Kitaoka Shiho. 【うつ病における炎症・酸化ストレスの役割と創薬への発展性】ストレスによる情動変容の誘導における炎症の役割. 日本生物学的精神医学会誌. 2018. 29. 4号. 168-172
Kitaoka Shiho, Furuyashiki Tomoyuki. ストレスによる脳内炎症現在の理解と今後の展望. 炎症と免疫. 2018. 26. 3号. 257-261
Akiko Sumitomo, Keisho Ueta, Kouta Horike, Shiho Kitaoka, Tomoyuki Furuyashiki, Takatoshi Hikida, Takeshi Sakurai, Akira Sawa, Toshifumi Tomoda, Shuh Narumiya. Elevated p62 and attenuated autophagy cause GABA receptor downregulation and underlie the pathophysiology of neuropsychiatric manifestation. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S221-S221

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Books (1)：

Lectures and oral presentations (34)：

マウス反復社会挫折ストレスによる前頭前皮質ミクログリアのエピゲノム変化の解析
(第92回日本薬理学会年会 2019)
マウスの社会挫折ストレスにより誘導される情動変容の多面的解析:社会忌避と不安亢進の解離
(第92回日本薬理学会年会 2019)
Repeated stress-induced behavioral changes and inflammation-like responses
(第92回日本薬理学会年会 2019)
反復社会挫折ストレスにより誘導される前頭前皮質ミクログリアのエピゲノム変化の解析
(新学術領域マルチスケール精神病態の構成的理解第1回領域会議 2019)
Repeated stress induces behavioral changes through inflammation-like response.
(Japan-UK Neuroscience Symposium 2019)

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Education (3)：

2002 - 2006 Osaka University Graduate School of Medicine
1999 - 2001 Osaka University Graduate School of Engineering Department of Material and Life Science
1995 - 1999 Osaka University School of Engineering

Professional career (2)：

Work history (6)：

2022/04 - 現在 Kwansei Gakuin University Graduate School of Science and Technology
2021/04 - 現在 Kobe University Graduate School of Medicine
2021/04 - 現在 Hyogo College of Medicine
2019/04 - 2021/03 Kobe University
2014/09 - 2019/03 Kobe University

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Committee career (3)：

Awards (2)：

Association Membership(s) (8)：

日本生理学会 , 日本生化学会 , 日本炎症・再生医学会 , 日本神経化学会 , 日本神経精神薬理学会 , 北米神経科学会 , 日本神経科学会 , 日本薬理学会

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