2019 - 2022 Study on a regeneration mechanism of corneal stroma in a decellularized scaffold and on the methods to construct corneal stromal like architecture
2016 - 2019 Development of soft nanoparticle composite materials based on decellularized tissues and its application to treatment of myocardial infarction
2014 - 2016 Neuroregeneration by concerted regulation of cellular microenvironments
2009 - 2011 脱細胞化角膜実質を用いた再生型人工角膜の開発と特性評価
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Papers (57)：
Jun Negishi, Ayana Yamaguchi, Dan Tanaka, Yoshihide Hashimoto, Yongwei Zhang, Seiichi Funamoto. A method for fabricating tissue-specific extracellular matrix blocks from decellularized tissue powders. Advanced Biology. 2024
Yoshihide Hashimoto, Jun Negishi, Seiichi Funamoto, Tsuyoshi Kimura, Hisatoshi Kobayashi, Tetsuro Oshika, Akio Kishida. Preparation, physico-biochemical characterization, and proteomic analysis of highly transparent corneal extracellular matrices for lamellar keratoplasty and tissue-engineered cornea construction. Materials Today Bio. 2024. 28. 101241
Jun Negishi, Dan Tanaka, Yoshihide Hashimoto. Induction of osteogenic differentiation by the extracellular matrix of fetal bone tissues and adult cartilage. Tissue and Cell. 2024. 90. 102475
Mako Kobayashi, Jun Negishi, Naoki Ishida, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida. Effects of the matrix-bounded nanovesicles of high-hydrostatic pressure decellularized tissues on neural regeneration. Science and Technology of Advanced Materials. 2024. 25. 1. 2404380
Ayana Yamaguchi, Yoshihide Hashimoto, Jun Negishi. Fabrication of a cell culture scaffold that mimics the composition and structure of bone marrow extracellular matrix. Journal of Bioscience and Bioengineering. 2024. 138. 1. 83-88
Sreypich Say, Mika Suzuki, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Fibroblast and THP-1 Cell Response to Multi-Arm PEGNHS-Modified Decellularized Porcine Pericardium. Materials Proceedings. 2024. 19. 1. 3
Yoshihide Hashimoto. Research and development on therapeutic materials for corneal stromal disease consisting of transparent decellularised porcine corneas. Impact. 2023. 2023. 3. 49-51
2015/10 - 2024/09 Tokyo Medical and Dental University Track of Life Science and Technology, Graduate School of Medical and Dental Sciences
2015/10 - 2023/03 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering, Division of Biofunctional Restoration
Committee career (4)：
2022/04 - 現在 日本バイオマテリアル学会 評議員
2018/01 - 現在 日本材料科学会 インフォマティク・バイオマテリアル基礎研究会 運営委員
2016/04 - 現在 ライフサポート学会 フロンティア講演会 管理委員
2017/04 - 2017/11 第39回日本バイオマテリアル学会大会 実行委員
Awards (5)：
2022/11 - 第44回日本バイオマテリアル学会大会 ハイライト講演
2020/11 - 日本人工臓器学会 2020年度 Yoshimi Memorial T.M.P Grant
2013/02 - The 16th International Symposium on Recent Advances in Drug Delivery Systems 2013 Young Scientist Poster Award
2010/11 - 第32回日本バイオマテリアル学会大会 若手研究者ポスター発表 大会長賞
2008/04 - National Institute for Materials Science Award for NIMS Internship Program 2008
Association Membership(s) (8)：
THE SOCIETY OF POLYMER SCIENCE, JAPAN
, THE SOCIETY OF LIFE SUPPORT ENGINEERING
, 日本脂質生化学会
, JAPANESE SOCIETY FOR ARTIFICIAL ORGANS
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
, 日本バイオマテリアル学会
, 日本生化学会
, 日本心臓血管外科学会
