2016 - 2021 Development of molecular targeted therapy for primary central nervous system lymphomas
2015 - 2020 Computational reconstruction of the higher-order structure of chromosomes and linkage analysis between chromosome structure and phenotype
2018 - 2020 次世代シーケンサーを用いた造血器腫瘍の発症機構および正常造血の研究
2015 - 2018 Longitudinal analyses of genetic alterations in malignant lymphoma using cell-free DNA: detection of refractory disease related abnormalities and application possibility in clinical trials.
2015 - 2017 Investigation of the pathogeneisis of myelodysplastic syndromes and its therapeutic biomarkers
2014 - 2015 Genetic analysis of clonal evolution and spatial heterogeneity in myelodysplastic syndromes
2012 - 2013 Identification of novel therapeutic targets in myelodysplastic syndromes using next-generation sequencing
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Papers (233)：
Kenichi Yoshida. Clonal hematopoiesis in cancer predisposition syndromes. International Journal of Hematology. 2024
Shinju Iyoda, Kenichi Yoshida, Kota Shoji, Nana Ito, Miu Tanaka, Yasuhito Nannya, Genki Yamato, Shinichi Tsujimoto, Norio Shiba, Yasuhide Hayashi, et al. KRAS G12 mutations as adverse prognostic factors in KMT2A-rearranged acute myeloid leukemia. Leukemia. 2024. 38. 7. 1609-1612
Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, et al. Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood Journal. 2024
Daniel Noerenberg, Franziska Briest, Cornelius Hennch, Kenichi Yoshida, Raphael Hablesreiter, Yasuhide Takeuchi, Hiroo Ueno, Annette M Staiger, Marita Ziepert, Fazila Asmar, et al. Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023. JCO2301053
Takahiro Aoki, Norio Shiba, Shinichi Tsujimoto, Genki Yamato, Yusuke Hara, Shota Kato, Kenichi Yoshida, Seishi Ogawa, Yasuhide Hayashi, Shotaro Iwamoto, et al. High IL2RA/CD25 expression is a prognostic stem cell biomarker for pediatric acute myeloid leukemia without a core-binding factor. Pediatric blood & cancer. 2023. e30803
Genki Yamato, Tomoko Kawai, Norio Shiba, Yusuke Hara, Kentaro Ohki, Taeko Kaburagi, Etsuko Ishikita, Hirohide Kawasaki, Kenichi Yoshida, Yuichi Shiraishi, et al. Prognosis of Pediatric Acute Myeloid Leukemia with KMT2A-MLLT3 According to DNA Methylation Patterns: Jccg JPLSG AML-05 Study. BLOOD. 2022. 140. 9134-9135
June Takeda, Kenichi Yoshida, Masahiro M. Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi, et al. Amplified EPOR/JAK2 genes definea unique subtype of acute erythroid leukemia. CANCER RESEARCH. 2022. 82. 12
Tomomi Nishimura, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhide Takeuchi, Hirona Maeda, Yusuke Shiozawa, Masahiro Hirata, Tatsuki R. Kataoka, Takaki Sakurai, Satoko Baba, et al. Clonal evolution of proliferative lesions into breast cancers. CANCER SCIENCE. 2021. 112. 157-157
Yasuhide Takeuchi, Hiromichi Suzuki, Kenichi Yoshida, Yuichi Shiraishi, Nobuyuki Kakiuchi, Yusuke Shiozawa, Yoshikage Inoue, Kenichi Chiba, Hideki Makishima, Satoru Miyano, et al. Frequent abnormalities in TP53 and increased genetic instability in myxofibrosarcoma. CANCER SCIENCE. 2021. 112. 850-850
June Takeda, Kenichi Yoshida, Akinori Yoda, Yasuhito Nannya, Masahiro Nakagawa, Yotaro Ochi, Ayana Kon, Tetsuichi Yoshizato, Yusuke Shiozawa, Yuichi Shiraishi, et al. JAK STAT Pathway is a Promising Therapeutic target in Acute Erythroid Leukemia. CANCER SCIENCE. 2021. 112. 453-453
2010 - 2014 The University of Tokyo Graduate School of Medicine
1999 - 2005 Tohoku University Faculty of Medicine
Professional career (1)：
Doctor of Philosophy (The University of Tokyo)
Work history (8)：
2022/04 - 現在 National Cancer Center Research Institute Division of Cancer Evolution Chief
2020/03 - 2022/03 Wellcome Sanger Institute Postdoctoral fellow
2018/02 - 2020/02 Overseas Research Fellowship, Japan Society for the Promotion of Science
2014/09 - 2018/02 Graduate School of Medicine, Kyoto University Department of Pathology and Tumor Biology Assistant Professor
2014/04 - 2014/08 Graduate School of Medicine, Kyoto University Department of Pathology and Tumor Biology Program-Specific Assistant Professor
2012/04 - 2014/03 Research Fellowship, Japan Society for the Promotion of Science
2007/04 - 2010/03 Senior Resident, Department of Pediatrics, St. Luke’s International Hospital
2005/04 - 2007/03 Junior Resident, St. Luke’s International Hospital
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Awards (5)：
2021/04 - Kiyoko Goto and Paul Bourdarie Cancer Foundation The 9th (2020) Kiyoko and Paul Bourdarie-Goto Scientific Prize Tobacco smoking and somatic mutations in human bronchial epithelium
2014/09 - Japanese Cancer Association Incitement Award of the Japanese Cancer Association
2014/02 - Nagoya International Cancer Treatment Symposium BMS Award in Nagoya Symposium Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia
2012/11 - The Japanese Society of Pediatric Hematology / Oncology Prize for Science from The Japanese Society of Pediatric Hematology/Oncology
2011/10 - The Japanese Society of Hematology Incitement Award of the Japanese Society of Hematology
Association Membership(s) (7)：
American Association for Cancer Research
, American Society of Hematology
, European Hematology Association
, Japanese Society of Hematology
, Japanese Cancer Association
, Japanese Society of Pediatric Hematology/Oncology
, Japan Pediatric Society
