Nishimura Shinichi

ニシムラシンイチ | Nishimura Shinichi

Affiliation and department：
Job title： Professor

Research field (3)： Chemical biology , Molecular biochemistry , Bioorganic chemistry

Research keywords (8)：天然物化学 , ケミカルバイオロジー , 細胞間コミュニケーション , 抗生物質 , 共生物質 , 生体膜脂質 , 金属錯体 , アミノ酸代謝

Research theme for competitive and other funds (16)：

2021 - 2024 マルチターゲットを有する膜脂質の化学オミクス解析
2019 - 2024 Innovative chemical genetics on novel function of endogenous metabolites
2021 - 2023 セリン代謝の化学遺伝学的解析
2017 - 2022 Chemical communications in microbial interactions and development of useful bioactive ligands
2018 - 2021 Identification of new natural products targeting cell membrane and analyses of their modes of action.

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Papers (76)：

Yojiro Hoshikawa, Natsuho Shirota, Hiroshi Tsugawa, Satoshi Kimura, Akihisa Matsuyama, Yoko Yashiroda, Hideaki Kakeya, Makoto Arita, Reiko Iizumi, Minoru Yoshida, et al. Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast. bioRxiv. 2024
Mayuki Sasaki, Shinichi Nishimura, Akihisa Matsuyama, Minoru Yoshida. Protocol for detecting threonine deaminase activity in fission yeast cell lysates. STAR Protocols. 2023. 4. 4. 102675-102675
Akihisa Matsuyama, Atsushi Hashimoto, Shinichi Nishimura, Minoru Yoshida. A set of vectors and strains for chromosomal integration in fission yeast. Scientific reports. 2023. 13. 1. 9295-9295
Mayuki Sasaki, Shinichi Nishimura, Yoko Yashiroda, Akihisa Matsuyama, Hideaki Kakeya, Minoru Yoshida. FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast. iScience. 2022. 25. 12. 105659-105659
Po-Chang Chiu, Yuri Nakamura, Shinichi Nishimura, Toshitsugu Tabuchi, Yoko Yashiroda, Go Hirai, Akihisa Matsuyama, Minoru Yoshida. Ferrichrome, a fungal-type siderophore, confers high ammonium tolerance to fission yeast. Scientific Reports. 2022. 12. 1

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MISC (35)：

竹中慧, 西村慎一, 金子賢介, LU Shan, 掛谷秀昭. Study on a new prodrug methodology inspired by a natural product saccharothriolide B. 日本薬学会年会要旨集(CD-ROM). 2020. 140th (Web)
浅水俊平, 尾崎太郎, 尾崎太郎, 西村慎一, 西村慎一, 掛谷秀昭, 尾仲宏康. 複合培養におけるStreptomyces sp.HEK616による5aTHQの生産機構. 日本農芸化学会大会講演要旨集(Web). 2019. 2019
浅水俊平, 浅水俊平, 尾崎太郎, 西村慎一, 掛谷秀昭, 尾仲宏康, 尾仲宏康. Streptomyces sp.HEK616とTsukamurella pulmonisとの複合培養での二次代謝活性化機構の解析. 日本放線菌学会大会講演要旨集. 2019. 34th
西村慎一, 掛谷秀昭, 松森信明. 生体膜を標的にする天然有機化合物天然物による厳密な脂質認識とそれに基づく表現型. 化学と生物. 2018. 56. 10. 678-685-684
西村慎一, 西村慎一, 杉山龍介, 仲谷崇宏, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭. Membrane Affinity and Biological Activities of 5aTHQs, Combined-culture Metabolites. 天然有機化合物討論会講演要旨集(Web). 2018. 60th

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Patents (5)：

Education (3)：

2001 - 2004 The University of Tokyo Graduate School of Agricultural and Life Sciences
1999 - 2001 The University of Tokyo Graduate School of Agricultural and Life Sciences
1995 - 1999 The University of Tokyo

Professional career (1)：

Work history (9)：

2023/01 - 現在 Hiroshima University Graduate School of Integrated Sciences for Life Professor
2021/04 - 2023/03 Meiji University Graduate School of Agriculture
2018/03 - 2022/12 The University of Tokyo Graduate School of Agricultural and Life Sciences Lecturer
2009/04 - 2018/02 Kyoto University Graduate School of Pharmaceutical Sciences Division of Bioinformatics and Chemical Genomics
2016/08 - 2017/08 University of California San Diego Scripps Institution of Oceanography

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Awards (2)：

Association Membership(s) (6)：

日本脂質生化学会 , 日本分子生物学会 , 日本農芸化学会 , 日本薬学会 , 酵母遺伝学フォーラム , 日本ケミカルバイオロジー学会

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