Sasai Miwa

ササイミワ | Sasai Miwa

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/30631551.ja.html

Research field (1)： Immunology

Research keywords (2)： Parasitology , Innate Immunity

Research theme for competitive and other funds (4)：

2018 - 2022 Pathogenic and genetic analysis of Toxoplasma by Japan, China and South Korea
2018 - 2022 The role of Atg family members on autophagy independent pathway
2014 - 2016 The regulation of cytokine production by phospholipid on MVB
2012 - 2014 Mechanism of antiviral responses by type-II Interferon

Papers (70)：

Masaaki Okamoto, Ayumi Kuratani, Daisuke Okuzaki, Naganori Kamiyama, Takashi Kobayashi, Miwa Sasai, Masahiro Yamamoto. IFN-γ-induced Th1-Treg polarization in inflamed brains limits exacerbation of experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 48. e2401692121
Yuki Nakayama, Fumiaki Ihara, Daisuke Okuzaki, Yoshifumi Nishikawa, Miwa Sasai, Masahiro Yamamoto. Toxoplasma GRA15 expression on dendritic cells inhibits B cell differentiation and antibody production. Parasitology international. 2024. 102995-102995
Yuta Tachibana, Miwa Sasai, Masahiro Yamamoto. CRISPR screens identify genes essential for in vivo virulence among proteins of hyperLOPIT-unassigned subcellular localization in Toxoplasma. mBio. 2024. 15. 9. e0172824
Masaaki Okamoto, Ayumi Kuratani, Daisuke Okuzaki, Naganori Kamiyama, Takashi Kobayashi, Miwa Sasai, Masahiro Yamamoto. Tff1-expressing Tregs in lung prevent exacerbation of Bleomycin-induced pulmonary fibrosis. Frontiers in immunology. 2024. 15. 1440918-1440918
Tokuju Okano, Hiroshi Ashida, Noriko Komatsu, Masayuki Tsukasaki, Tamako Iida, Marie Iwasawa, Yuto Takahashi, Yasuo Takeuchi, Takanori Iwata, Miwa Sasai, et al. Caspase-11 mediated inflammasome activation in macrophages by systemic infection of A. actinomycetemcomitans exacerbates arthritis. International journal of oral science. 2024. 16. 1. 54-54

ｍore...

MISC (3)：

Miwa Sasai, Masahiro Yamamoto. Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. CYTOKINE. 2017. 100. 29-29
Payal Mehta, Jill Henault, Jennifer Martinez, Jeffery Riggs, Jane Tian, Lorraine Clarke, Miwa Sasai, Eicke Latz, Melanie Brinkmann, Akiko Lwasaki, et al. LC3-associated phagocytosis mediates IFN-alpha secretion in response to DNA-immune complexes. JOURNAL OF IMMUNOLOGY. 2014. 192
Michal Tal, Miwa Sasai, Akiko Iwasaki. RLR signaling is amplified by reactive oxygen species and dysfunctions in autophagy. JOURNAL OF IMMUNOLOGY. 2011. 186

Books (2)：

Lectures and oral presentations (30)：

Uncovering a novel role of PLCb in selectively mediating TCR signaling in CD8+ but not CD4+ T cells
(第43回分子生物学会・ワークショップ (口頭) 2020)
PLCβ plays an important role in CD8 T cell-mediated host defense against Toxoplasma gondii
(第46回日本免疫学会学術集会 2017)
Role of GABARAP subfamily in the regulation of non-canonical inflammasome activation
(第46回日本免疫学会学術集会 2017)
Critical roles of GABARAPs on interferon-mediated cell-autonomous immune responses against T. gondii infection
(第46回日本免疫学会学術集会 2017)
Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases
(CYTOKINE2017 2017)

ｍore...

Work history (5)：

Awards (5)：

2018/11 - 大阪大学大阪大学賞
2018/04 - 文部科学省文部科学大臣表彰・若手科学者賞
2018/04 - 文部科学省若手科学者賞細胞内小胞輸送を介した病原体排除機構に関する研究
2017/12 - Japanese Society for Immunology(JSI) 2017 JSI Young Investigator Award
2017/12 - Japanese Society for Immunology (JSI) JSI Young Investigator Award

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page