Rchr
J-GLOBAL ID：201401016101271562
Update date: Feb. 01, 2024
Imasaki Tsuyoshi
イマサキ ツヨシ | Imasaki Tsuyoshi
Affiliation and department：
Job title：
Assistant Professor
Research field (4)：
Cell biology
, Structural biochemistry
, Morphology, anatomy
, Anatomy
Research keywords (10)：
Anatomy
, cell biology
, MAPs
, Microtubule
, Electron microscopy
, Transcription
, Mediator
, Recombinant multi-protein complex
, Multi-protein complex
, X-ray crystallography
Research theme for competitive and other funds (5)：
- 2022 - 2027 Mechanism of microtubule based cell polarity formation in situ
- 2021 - 2027 革新的化合物探索・合成手法による新規抗菌アジュバントの創出
- 2022 - 2025 a
- 2019 - 2022 Structural study of Mediator CDK module
- 2014 - 2018 Structure determination of Mediator CDK module
Papers (26)：
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Hiromichi Okuma, Yumiko Saijo-Hamano, Hiroshi Yamada, Aalaa Alrahman Sherif, Emi Hashizaki, Naoki Sakai, Takaaki Kato, Tsuyoshi Imasaki, Satoshi Kikkawa, Eriko Nitta, et al. Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch. Genes to Cells. 2023
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Tsuyoshi Imasaki, Ryo Nitta. The molecular mechanism of non-centrosomal microtubule nucleation. Seikagaku. 2023
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Shintaro Yamada, Toshiyuki Ko, Masamichi Ito, Tatsuro Sassa, Seitaro Nomura, Hiromichi Okuma, Mayuko Sato, Tsuyoshi Imasaki, Satoshi Kikkawa, Bo Zhang, et al. TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy. Science Advances. 2023. 9. 15
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Shinya Taguchi, Juri Nakano, Tsuyoshi Imasaki, Tomoki Kita, Yumiko Saijo-Hamano, Naoki Sakai, Hideki Shigematsu, Hiromichi Okuma, Takahiro Shimizu, Eriko Nitta, et al. Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex. eLife. 2022
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Tsuyoshi Imasaki, Satoshi Kikkawa, Shinsuke Niwa, Yumiko Saijo-Hamano, Hideki Shigematsu, Kazuhiro Aoyama, Kaoru Mitsuoka, Takahiro Shimizu, Mari Aoki, Ayako Sakamoto, et al. CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation. eLife. 2022. 11
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MISC (1)：
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Francisco J. Asturias, Gang Cai, Tsuyoshi Imasaki, Kentaro Yamada, Francesco Cardelli, Yuichiro Takagi. Mediator Structure and Interaction with the Basal Transcription Machinery. FASEB JOURNAL. 2010. 24
Books (2)：
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イメージング時代の構造生命科学 : 細胞の動態、膜のないオルガネラ、分子の構造変化をトランススケールに観る
羊土社 2020 ISBN:9784758103855
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新しい臨床を開拓するための分子循環器病学
南山堂 2019 ISBN:9784525249410
Lectures and oral presentations (10)：
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微小管による細胞極性形成制御機構の構造研究
(日本顕微鏡学会第 65 回シンポジウム 2022)
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拡張型心筋症の病態解明に向けた FIB-SEM〜クライオTEMの試み
(日本顕微鏡学会 生体解析分科会研究会 「バイオ向けクライオ透過電子顕微鏡の多様性の最前線3」 2022)
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Practical methods for in situ structural biology on clinical samples
(2022)
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Structural basis of microtubule dynamics inhibition by Kinesin-4
(The 127th Annual Meeting of The Japanese Association of Anatomists 2022)
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Applications of in situ cryo electron microscopy in biology and medicine
(The 64th Symposium of The Japanese Society of Microscopy 2021)
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Education (1)：
- - 2007 横浜市立大学 大学院総合理学研究科博士後期課程修了
Professional career (1)：
Work history (6)：
Awards (1)：
- 2018/10 - Kobe University Shinryoku-kai Young Investigator Award
Association Membership(s) (2)：
The Japanese Association of Anatomists
, The Molecular Biology Society of Japan
