A FUJIMOTO

フジモトアキヒロ | A FUJIMOTO

Affiliation and department：
Job title： Professor
Other affiliations (1)：

理化学研究所

Homepage URL (1)： http://kaken.nii.ac.jp/d/r/30525853.ja.html

Research field (1)： Medical biochemistry

Research keywords (15)：全ゲノムシークエンス , ゲノムワイド関連解析 , 癌 , 統計数学 , がんゲノム , ゲノム , 遺伝統計学 , 遺伝学 , 遺伝子 , 日本人ゲノム , 構造多型 , 次世代シークエンサー , 国際がんゲノムコンソーシアム , 多様性 , コピー数多型

Research theme for competitive and other funds (16)：

2023 - 2027 長鎖シークエンス技術を用いた腫瘍の転写産物全長の解析
2023 - 2027 長鎖シークエンス技術を用いた腫瘍の転写産物全長の解析
2021 - 2024 長鎖シークエンス法の転写産物解析による非コード領域の発癌への寄与の解明
2020 - 2023 「missing heritability」問題解決に向けた人類遺伝学研究
2018 - 2023 Deciphering Origin and Establishment of Japonesians mainly based on genome sequence data

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Papers (79)：

Wittawin Worakitchanon, Hideki Yanai, Pundharika Piboonsiri, Reiko Miyahara, Supalert Nedsuwan, Worarat Imsanguan, Boonchai Chaiyasirinroje, Waritta Sawaengdee, Sukanya Wattanapokayakit, Nuanjan Wichukchinda, et al. Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence. Cell Host & Microbe. 2024. 32. 11. 1972-1987.e6
Motoko Unoki, Shuhei Uemura, Akihiro Fujimoto, Hiroyuki Sasaki. The maternal protein NLRP5 stabilizes UHRF1 in the cytoplasm: Implication for the pathogenesis of multilocus imprinting disturbance. Human Molecular Genetics. 2024. in press
Dan Tomomasa, Beom Hee Lee, Yuki Hirata, Yuzaburo Inoue, Hidetaka Majima, Yusuke Imanaka, Takaki Asano, Takashi Katakami, Jina Lee, Atsushi Hijikata, et al. Inherited CARD9 Deficiency Due to a Founder Effect in East Asia. Journal of Clinical Immunology. 2024. 44. 5
Mihoko Shimada, Yosuke Omae, Akiyoshi Kakita, Ramil Gabdulkhaev, Yuki Hitomi, Taku Miyagawa, Makoto Honda, Akihiro Fujimoto, Katsushi Tokunaga. Identification of region-specific gene isoforms in the human brain using long-read transcriptome sequencing. Science advances. 2024. 10. 4. eadj5279
Kugui Yoshida-Tanaka, Ko Ikemoto, Ryoji Kuribayashi, Motoko Unoki, Takako Takano, Akihiro Fujimoto. Long-read sequencing reveals the complex structure of extra dic(21;21) chromosome and its biological effects. HUMAN GENETICS. 2023

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MISC (21)：

Masashi Fujita, Rui Yamaguchi, Takanori Hasegawa, Shu Shimada, Koji Arihiro, Shuto Hayashi, Kazuhiro Maejima, Kaoru Nakano, Akihiro Fujimoto, Atsushi Ono, et al. Classification of Primary Liver Cancer with Immunosuppression Mechanisms and Correlation with Genomic Alterations (vol 52, 102, 2021). EBIOMEDICINE. 2021. 66
竹田治彦, 高井淳, 藤本明洋, 藤本明洋, 恵荘裕嗣, 高橋健, 上田佳秀, 上田佳秀, 田浦康二朗, 上本伸二, et al. 結節内結節型肝癌の全ゲノムシーケンス解析を用いた新規標的分子同定の試み. Pharma Medica. 2020. 38. 12
Takayuki Sumiyoshi, Shusuke Akamatsu, Toshinari Yamasaki, Kei Mizuno, Takayuki Goto, Naoki Terada, Takashi Kobayashi, Takahiro Inoue, Tomomi Kamba, Akihiro Fujimoto, et al. ANDROGEN RECEPTOR GENE ABERRATIONS IN CIRCULATING CELL FREE DNA FROM JAPANESE CASTRATION RESISTANT PROSTATE CANCER PATIENTS. JOURNAL OF UROLOGY. 2018. 199. 4. E367-E367
Masashi Fujita, Nagahide Matsubara, Ikuo Matsuda, Tomoki Yamano, Akihiro Fujimoto, Satoru Miyano, Naohiro Tomita, Seiichi Hirota, Hiroki Ikeuchi, Hidewaki Nakagawa. Precision oncology by genomic profiling for colitic cancer indicates potentials for cancer diagnosis and treatment. CANCER SCIENCE. 2018. 109. 834-834
田中梓, 安永純一朗, 藤本明洋, 松岡雅雄. 成人T細胞白血病細胞のクロマチン構造解析. 日本HTLV-1学会学術集会. 2017. 4th. 54

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Professional career (1)：

博士(保健学) (東京大学)

Work history (4)：

2019/07 - 現在 The University of Tokyo Graduate School of Medicine
2016/04 - 2019/06 Kyoto University
2010/04 - 2016/03 RIKEN
2008/04 - 2010/03 RIKEN

Awards (9)：

2017/07 - 大正富山Award
2017/04 - 平成29年度文部科学大臣表彰若手科学者賞
2016 - 第8回理化学研究所・研究奨励賞
2016 - 第35回日本癌学会奨励賞
2016 - 2016年度日本人類遺伝学会奨励賞

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