Rchr
J-GLOBAL ID：201401041344127804   Update date: Feb. 01, 2024

Akiko Ibuka

イブカ アキコ | Akiko Ibuka
Affiliation and department：
Kanagawa University Faculty of Science Department of Biological Sciences

About Kanagawa University Faculty of Science Department of Biological Sciences


Job title： Professor
Research field  (3)： Applied biochemistry ,  Bacteriology ,  Food sciences
Research keywords  (9)： タンパク質科学 ,  薬剤耐性 ,  structural biology ,  酵素学 ,  enzyme ,  sweet protein ,  構造生物学 ,  酵素 ,  甘味タンパク質
Research theme for competitive and other funds  (5)：
  • 2019 - 2022 Analysis of unknown activity of metallo-beta-lactamase and search for novel inhibitors
  • 2019 - 呈味性に優れた塩味増強物質の開発に向けた塩味センシング技術の創出と検証
  • 2015 - 2019 Analysis of taste-modifying mechanism of miraculin using miraculin-like proteins
  • 2014 - 2017 Peripheral Response to Tastant Signals and Central Cognition for Analysis of Their Coordination and its Application to the Science of Food for Life
  • 2012 - 2015 Analysis of taste-recognition mechanism through taste receptor
Papers (48)：
  • Akiko Shimizu-Ibuka, Aoi Sato, Hikaru Ichimura, Haruna Hiraga, Shiori Nakayama, Toshikazu Nishiwaki. Regulation of alanine racemase activity by carboxylates and the d-type substrate d-alanine. The FEBS journal. 2023. 290. 11. 2954-2967
  • Tatsuya Ishikawa, Nayuta Furukawa, Emilia Caselli, Fabio Prati, Magdalena A. Taracila, Christopher R. Bethel, Yoshikazu Ishii, Akiko Shimizu-Ibuka, Robert A. Bonomo. Insights into the inhibition of MOX-1 β-lactamase by S02030, a boronic acid transition state inhibitor. Front. Microbiol. 2021. 12
  • Yoshiki Kato, Masayuki Takahashi, Mineaki Seki, Masayuki Nashimoto, Akiko Shimizu-Ibuka. RNA-hydrolyzing activity of metallo-β-lactamase IMP-1. PLOS One. 2020. 15. 10. e0241557
  • Ohkura,S, Hori,M, Saitoh,K, Okuzawa,T, Okamoto,I, Furukawa,N, Shimizu-Ibuka,A. Structural and functional analysis of miraculin-like protein fromVitis vinifera. Biochim. Biophys. Acta Proteins Proteom. 2018. 1866. 11. 1125-1130
  • Takamitsu Furuyama, Haruka Nonomura, Yoshikazu Ishii, Nancy D. Hanson, Akiko Shimizu-Ibuka. Structural and mutagenic analysis of metallo-β-lactamase IMP-18. Antimicrobial Agents and Chemotherapy. 2016. 60. 9. 5521-5526
ｍore...
Lectures and oral presentations  (6)：
  • メタロβ-ラクタマーゼIMP-1のRNA加水分解活性
    (日本生化学会2020年度大会 2020)
  • メタロ-β-ラクタマーゼIMP-1における亜鉛結合解析
    (日本農芸化学会2019年大会 2019)
  • <I>Lactobacillus sakei</I>Uonuma株由来アラニンラセマーゼ(AlaR)の解析
    (日本農芸化学会2019年大会 2019)
  • <I>Lactobacillus sakei </I>Uonuma株由来アラニンラセマーゼ(AlaR)の解析
    (日本農芸化学会2019年大会 2019)
  • Overcoming Extended spectrum AmpC β-lactamases with boronic acid transition state inhibitors; crystal structure of MOX-1 complexed with S02030.
    (ASM microbe 2018 2018)
ｍore...
Works (1)：
  • Neoculin as a new sweet protein with taste-modifying activity: purification, characterization, and X-ray crystallography
    Shimizu-Ibuka,A, Morita,Y, Nakajima,K, Asakura,T, Terada,T, Misaka,T, Abe,K 2008 -
Education (3)：
  • 1995 - 1997 The University of Tokyo
  • 1993 - 1995 The University of Tokyo Graduate School, Division of Agriculture
  • 1989 - 1993 The University of Tokyo Faculty of Agriculture
Professional career (3)：
  • 学士(農学) (東京大学)
  • 修士(農学) (東京大学大学院)
  • 博士(農学) (東京大学大学院)
Work history (8)：
  • 2022/04 - 現在 Kanagawa University
  • 2014/09 - 2022/03 Niigata University of Pharmacy and Applied Life Sciences Faculty of Applied Life Sciences Department of Applied Life Sciences
  • 2011/04 - 2014/08 山形大学 理学部物質生命化学科 准教授
  • 2009/04 - 2011/03 The University of Tokyo Graduate School of Agricultural and Life Sciences Applied Biological Chemistry
  • 2007/04 - 2009/03 東京農業大学 応用生物科学部 栄養科学科 専任講師
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Association Membership(s) (4)：
American Society for Microbiology ,  American Chemical Society ,  日本生化学会 ,  日本農芸化学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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