Rchr
J-GLOBAL ID:201401044256358595
Update date: Nov. 05, 2024
Yamaguchi Hiroshi
ヤマグチ ヒロシ | Yamaguchi Hiroshi
Affiliation and department:
Job title:
Designated assistant professor
Research field (3):
Cell biology
, Molecular biology
, Neuroscience - general
Research keywords (6):
冬眠
, gene editing
, optogenetics
, metabolism
, hibernation
, torpor
Research theme for competitive and other funds (4):
- 2023 - 2027 脳と大腸を機能連関させる神経回路のリモデリングとその排便異常への関与
- 2021 - 2024 概日時計による体温調節メカニズムの解明
- 2020 - 2023 中枢神経による大腸運動制御機構と排便異常に認められる性差のメカニズム解明
- 2011 - 2012 Identification of the factor released from apoptotic cells that regulates the gene expressions in macrophages
Papers (16):
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Hiroshi Yamaguchi. Hypothalamic control of torpor and hibernation. Temperature. 2024
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Hiroshi Yamaguchi, Keith R. Murphy, Noriaki Fukatsu, Kazuhide Sato, Akihiro Yamanaka, Luis de Lecea. Dorsomedial and preoptic hypothalamic circuits control torpor. Current Biology. 2023
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Tomoya Sawamura, Natsufu Yuki, Kazuhiro Horii, Kiyotada Naitou, Hiroshi Yamaguchi, Akihiro Yamanaka, Takahiko Shiina, Yasutake Shimizu. Essential roles of the hypothalamic A11 region and the medullary raphe nuclei in regulation of colorectal motility in rats. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2023
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Hiroshi Yamaguchi, Keith R Murphy, Noriaki Fukatsu, Kazuhide Sato, Akihiro Yamanaka, Luis de Lecea. Brain-wide mapping of neuronal architecture controlling torpor. 2023
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Shi-Bin Li, Valentina Martinez Damonte, Chong Chen, Gordon X. Wang, Justus M. Kebschull, Hiroshi Yamaguchi, Wen-Jie Bian, Carolin Purmann, Reenal Pattni, Alexander Eckehart Urban, et al. Hyperexcitable arousal circuits drive sleep instability during aging. Science. 2022. 375. 6583
more...
MISC (3):
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山口裕嗣. トーパーの神経メカニズム. 医学のあゆみ. 2021. 277. 3. 231-234
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山本 奈つき, 大村 浩一郎, 山口 裕嗣, 湯川 尚一郎, 吉藤 元, 川端 大介, 臼井 崇, 藤井 隆夫, 長田 重一, 三森 経世. MFG-E8陽性全身性エリテマトーデスの臨床的特徴. 日本内科学会雑誌. 2012. 101. Suppl. 319-319
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山口 裕嗣, 長田 重一. 【細胞死研究 総集編】細胞死の関わる生命現象 細胞貪食 MFG-E8およびTim4を介したアポトーシス細胞の認識・貪食機構とその破綻. 実験医学. 2010. 28. 7. 1048-1054
Books (1):
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MFG-E8およびTim4を介したアポトーシス細胞の認識・貪食機構とその破綻 実験医学増刊 細胞死研究総集編
羊土社 2010
Lectures and oral presentations (5):
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Dorsal Medial Hypothalamus GABA Neurons that Regulate Torpor -Potential Application to Space Missions.
(NASA Ames space torpor workshop 2018)
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Awakening actions of norepinephrine probed with cell type-specific CRISPR gene editing in locus coeruleus.
(SfN’s 47th annual meeting 2017)
-
Immunosuppression via adenosine receptor activation by AMP released from apoptotic cells.
(Keystone Symposia on Molecular Cell Biology of Macrophages in Human Diseases 2014)
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Release by apoptotic cells of a factor(s) that regulates the gene expression in macrophages.
(13th International TNF Conference 2011)
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SLE患者血中におけるMFG-E8
(第17回日本アポトーシス研究会学術集会 2008)
Education (3):
- 2004 - 2009 Osaka University
- 2004 - 2009 大阪大学大学院 生命機能研究科
- 2000 - 2004 The University of Tokyo
Professional career (1):
Work history (6):
Association Membership(s) (3):
日本分子生物学会
, 日本神経科学会
, 日本生理学会
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