Ninomiya Kensuke

Affiliation and department：
Job title：特任講師

Research field (1)： Molecular biology

Research theme for competitive and other funds (6)：

2022 - 2025 Functional analysis of multi-functional short-tandem repeat RNAs
2019 - 2021 核内ストレス体の構成変動に着目したストレス応答機構の解明
2015 - 2016 トランスクリプトームの人為的操作による遺伝病の治療
2014 - 2016 新規スプライシング調節機構によるDNA損傷修復モデルの立証と解析
2012 - 2015 Identification of a small molecule that induces autophagy-mediated degradation of TAU

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Papers (18)：

Tetsuya Yamamoto, Tomohiro Yamazaki, Kensuke Ninomiya, Tetsuro Hirose. Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus. Communications Biology. 2023. 6. 1
Kensuke Ninomiya, Tomohiro Yamazaki, Tetsuro Hirose. Satellite RNAs: emerging players in subnuclear architecture and gene regulation. The EMBO journal. 2023. e114331
Tetsuro Hirose, Kensuke Ninomiya, Shinichi Nakagawa, Tomohiro Yamazaki. A guide to membraneless organelles and their various roles in gene regulation. Nature reviews. Molecular cell biology. 2022
Kensuke Ninomiya, Junichi Iwakiri, Mahmoud Khamis Aly, Yuriko Sakaguchi, Shungo Adachi, Tohru Natsume, Goro Terai, Kiyoshi Asai, Tsutomu Suzuki, Tetsuro Hirose. m6A modification of HSATIII lncRNAs regulates temperature-dependent splicing. The EMBO Journal. 2021. 40. 15. e107976
Tomonori Shibata, Konami Nagano, Morio Ueyama, Kensuke Ninomiya, Tetsuro Hirose, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, Kazuhiko Nakatani. Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model. Nature Communications. 2020. 12. 1. 236-236

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MISC (17)：

上野剛志, 足達俊吾, 二宮賢介, 廣瀬哲郎, 廣瀬哲郎, 廣瀬哲郎. Chained phosphorylation that drives thermo-sensitive splicing regulation by nuclear stress bodies. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
二宮賢介, 足達俊吾, 廣瀬哲郎, 廣瀬哲郎. The multifunctionality of HSATIII lncRNAs and its control mechanisms. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
上野剛志, 足達俊吾, 二宮賢介, 廣瀬哲郎, 廣瀬哲郎, 廣瀬哲郎. Identification and analysis of regulatory proteins responsible for temperature-dependent recruitment of CLK1 to nuclear stress bodies. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
二宮賢介, ALY Mahmoud Khamis, 坂口裕理子, 足達俊吾, 夏目徹, 岩切淳一, 寺井悟朗, 浅井潔, 鈴木勉, 廣瀬哲郎. 核内ストレス体による2つのスプライシング制御機構. 日本RNA学会年会要旨集. 2019. 21st
二宮賢介, ALY Mahmoud Khamis, 坂口裕理子, 足達俊吾, 夏目徹, 岩切淳一, 寺井悟朗, 浅井潔, 鈴木勉, 廣瀬哲郎. HSATIII lncRNAによる2つのスプライシング制御機構. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd

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Books (3)：

Lectures and oral presentations (34)：

HSATIII lncRNAのm6A修飾と多機能性
(遺伝研研究会「エピトランスクリプトーム制御の分子機構と生理機能」 2024)
Short-tandem repeat型RNAであるHSATIIIの多彩な分子機能
(RNAフロンティアミーティング2023 2323)
Characterization and functional analysis of HSATIII-derived repetitive proteins
(第24回日本RNA学会年会 2023)
HSATIII lncRNAの多機能性とその制御機構
(第45回日本分子生物学会年会 2022)
The dynamics and functions of cytoplasmic HSATIII lncRNAs
(The 23nd Annual Meeting of the RNA Society of Japan 2022)

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Professional career (1)：

Association Membership(s) (2)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , The RNA Society of Japan

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