Rchr
J-GLOBAL ID:201401055208557618   Update date: Nov. 15, 2024

Fujita Hiroaki

フジタ ヒロアキ | Fujita Hiroaki
Affiliation and department:
Job title: assistant professor
Research field  (1): Applied molecular and cellular biology
Research theme for competitive and other funds  (8):
  • 2022 - 2025 鉄誘導性フェロトーシス惹起機構の解明
  • 2022 - 2024 鉄誘導性フェロトーシスを制御する新たな生命金属動態の解明
  • 2020 - 2022 過剰鉄によるフェロトーシス惹起メカニズムの解明
  • 2020 - 2022 鉄濃度依存的なフェリチンのオートファジー経路選択性の解析
  • 2019 - 2022 Elucidation of the mechanisms of cell survival and death by linear ubiquitin chains
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Papers (16):
  • Yusuke Toda, Hiroaki Fujita, Koshiki Mino, Takuto Koyama, Seiji Matsuoka, Toshie Kaizuka, Mari Agawa, Shigeyuki Matsumoto, Akiko Idei, Momoko Nishikori, et al. Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function. Cell Death & Disease. 2024. 15. 11
  • Hiroaki Fujita, Yu-Ki Tanaka, Seiryo Ogata, Noriyuki Suzuki, Sota Kuno, Uladzimir Barayeu, Takaaki Akaike, Yasumitsu Ogra, Kazuhiro Iwai. PRDX6 augments selenium utilization to limit iron toxicity and ferroptosis. Nature structural & molecular biology. 2024
  • Yukiko Takeda, Masahiro Ueki, Junpei Matsuhiro, Erik Walinda, Takayuki Tanaka, Masafumi Yamada, Hiroaki Fujita, Shunichiro Takezaki, Ichiro Kobayashi, Sakura Tamaki, et al. A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine. 2024. 221. 6
  • Kentaro Akagi, Shiro Baba, Hiroaki Fujita, Yasuhiro Fuseya, Daisuke Yoshinaga, Hirohito Kubota, Eitaro Kume, Fumiaki Fukumura, Koichi Matsuda, Takayuki Tanaka, et al. HOIL-1L deficiency induces cell cycle alteration which causes immaturity of skeletal muscle and cardiomyocytes. Scientific reports. 2024. 14. 1. 8871-8871
  • Sota Kuno, Hiroaki Fujita, Yu-Ki Tanaka, Yasumitsu Ogra, Kazuhiro Iwai. Iron-induced NCOA4 condensation regulates ferritin fate and iron homeostasis. EMBO reports. 2022. 23. 5. e54278
more...
MISC (5):
Books (3):
  • フェロトーシスとセレン代謝
    週刊 医学のあゆみ 2024
  • 直鎖状ポリユビキチン鎖による細胞機能制御
    シグナリング研究2015(羊土社) 2015
  • 直鎖状ポリユビキチン鎖による免疫・炎症反応の制御
    医学のあゆみ(医歯薬出版社) 2012
Lectures and oral presentations  (14):
  • Mechanisms underlying iron-induced ferroptosis: possibile involvement of selenium metabolism
    (The 1st international G-RE-XS Conference 2024)
  • 鉄依存性フェロトーシスの制御メカニズム解明
    (日本生化学会 2023)
  • 鉄誘導性フェロトーシスの制御メカニズム解明
    (1. メタルバイオサイエンス研究会 2022)
  • 過剰鉄によるフェロトーシス制御因子の解明
    (2. 日本生化学会 2021)
  • Mathematical modeling of biological systems that regulate cell survival and death
    (2019)
more...
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