Rchr
J-GLOBAL ID:201401055535111208   Update date: May. 01, 2024

Yuta Murai

Yuta Murai
Affiliation and department:
Research field  (1): Bioorganic chemistry
Research keywords  (6): infertility treatment ,  sphingolipid ,  Alzheimer's disease ,  生物有機化学 ,  光アフィニティーラベル法 ,  ケミカルバイオロジー
Research theme for competitive and other funds  (10):
  • 2024 - 2027 皮下深部の非浸潤癌診断を目指した短波赤外蛍光色素イメージング技術の開発
  • 2022 - 2025 スフィンゴミエリン合成酵素2阻害剤による腫瘍免疫亢進を介した新規抗癌治療の開発
  • 2021 - 2024 スフィンゴ脂質病の新規治療法を指向した光キャプチャーによるSMS2阻害様式の解明
  • 2019 - 2023 Development of novel stereochemical analytical technique of biomolecules by the VCD exciton chirality method
  • 2018 - 2021 Design of ligand-tag exchangeable new photoaffinity probe utilizing nosyl chemistry
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Papers (57):
  • Mahadeva M. M. Swamy, Yuta Murai, Kenji Monde, Setsuko Tsuboi, Aravind K. Swamy, Takashi Jin. Biocompatible and Water-Soluble Shortwave-Infrared (SWIR)-Emitting Cyanine-Based Fluorescent Probes for In Vivo Multiplexed Molecular Imaging. ACS Applied Materials & Interfaces. 2024
  • Hiroko Ikushiro, Takumi Honda, Yuta Murai, Taiki Murakami, Aya Takahashi, Taiki Sawai, Haruna Goto, Shin-ichi Ikushiro, Ikuko Miyahara, Yoshio Hirabayashi, et al. Racemization of the substrate and product by serine palmitoyltransferase from Sphingobacterium multivorum yields two enantiomers of the product from d-serine. Journal of Biological Chemistry. 2024
  • Wen Zhang, Kazu Sunami, Shuo Liu, Zihan Zhuang, Yasuko Sakihama, Da-Yang Zhou, Takeyuki Suzuki, Yuta Murai, Makoto Hashimoto, Yasuyuki Hashidoko. Accumulation of squalene in filamentous fungi Trichoderma virens PS1-7 in the presence of butenafine hydrochloride, squalene epoxidase inhibitor. -Biosynthesis of 13C-enriched squalene. Bioscience, Biotechnology, and Biochemistry. 2023
  • Hiroko Ikushiro, Taiki Murakami, Aya Takahashi, Asuka Katayama, Taiki Sawai, Haruna Goto, Sajeer Koolath, Yuta Murai, Kenji Monde, Ikuko Miyahara, et al. Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. Journal of Biological Chemistry. 2023. 299. 5. 104684-104684
  • Mariam Abdelrasoul, Kohei Yuyama, Mahadeva M. M. Swamy, Yuta Murai, Kenji Monde. Stereochemistry-activity relationship of ceramide-induced exosome production to clear amyloid-β in Alzheimer's disease. Chirality. 2023. 35. 9. 577-585
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MISC (12):
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Education (1):
  • 2010 - 2013 Hokkaido University Graduate School of Agriculture
Professional career (1):
  • 農学博士 (北海道大学)
Work history (4):
  • 2023/04 - 現在 Hokkaido University Graduate School of Agriculture Research Faculty of Agriculture
  • 2013/08 - 現在 Hokkaido University Faculty of Advanced Life Science
  • 2020/05 - 2023/03 理化学研究所 客員研究員
  • 2013/04 - 2013/07 Ritsumeikan University
Awards (3):
  • 2024/03 - 日本農芸化学会 2024年度農芸化学奨励賞
  • 2024/02 - 日本化学会北海道支部 日本化学会北海道支部奨励賞
  • 2023/11 - セラミド研究会 Young Investigator Award
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