Rchr
J-GLOBAL ID：201401057888566562   Update date: Sep. 28, 2024

Hori Kei

ホリ ケイ | Hori Kei
Affiliation and department：
National Center of Neurology and Psychiatry

About National Center of Neurology and Psychiatry


Homepage URL  (1)： http://kaken.nii.ac.jp/d/r/70568790.ja.html
Research field  (5)： Neuropathology ,  Developmental biology ,  Psychiatry ,  Basic brain sciences ,  Neuroscience - general
Research keywords  (16)： psychiatric disorders ,  Epigenetics ,  neurodevelopment ,  精神発達障害 ,  Polycomb ,  spine ,  synapse ,  Adult neurogenesis ,  hippocampus ,  Cerebral cortrex ,  神経突起伸長 ,  Racシグナリング ,  アクチン細胞骨格 ,  AUTS2 ,  自閉症 ,  神経細胞移動
Research theme for competitive and other funds  (6)：
  • 2022 - 2025 シナプス発達に関わる自閉症関連遺伝子AUTS2の新規転写制御機構の解明
  • 2016 - 2018 生後発達期大脳における自閉症感受性遺伝子Auts2の生理機能の解明
  • 2016 - 2017 精神疾患病態解明に向けた自閉症感受性遺伝子Auts2の生理機能の解明
  • 2013 - 2014 自閉症発症機序の解明に向けた新規自閉症感受性遺伝子Auts2の分子機能の解析
  • 2011 - 2012 小脳発達における新規自閉症感受性遺伝子Auts2の分子機能の解明
Show all
Papers (32)：
  • Ken-ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U. Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, et al. Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation. Nature Communications. 2024. 15. 1
  • Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2023. 12. RP89376
  • Yasumasa Hashimoto, Hiroshi Kuniishi, Kazuhisa Sakai, Yuta Fukushima, Xuan Du, Kunihiko Yamashiro, Kei Hori, Michihiro Imamura, Mikio Hoshino, Mitsuhiko Yamada, et al. Brain Dp140 alters glutamatergic transmission and social behaviour in the mdx52 mouse model of Duchenne muscular dystrophy. Progress in Neurobiology. 2022. 102288-102288
  • Yukiko U. Inoue, Hideki Miwa, Kei Hori, Ryosuke Kaneko, Yuki Morimoto, Eriko Koike, Junko Asami, Satoshi Kamijo, Mitsuhiko Yamada, Mikio Hoshino, et al. Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation. eNeuro. 2022. 9. 1. ENEURO.0423-21.2022
  • Kei Hori, Kazumi Shimaoka, Mikio Hoshino. AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders. Cells. 2021. 11. 1
ｍore...
MISC (4)：
  • 嶋岡可純, 堀啓, 井上由紀子, 郷康弘, 阿部学, 崎村建司, 井上高良, 星野幹雄. 自閉症感受性遺伝子AUTS2はマウス大脳皮質において上層神経細胞の産生に関与する. 日本神経化学会大会抄録集(Web). 2022. 65th
  • AUTS2症候群とAUTS2遺伝子. Clinical Neuroscience. 2020. 1561-1563
  • 堀啓, 山城邦比古, 永井拓, WEI Shan, 江草早紀, 嶋岡可純, 郷康宏, 辰本将司, 菅野康太, 坂本亜沙美, et al. 自閉症感受性遺伝子Auts2変異により引き起こるシナプス形成障害およびマウス行動異常の病態解析. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
  • 江草 早紀, 堀 啓, 坂本 亜沙美, 阿部 学, 崎村 建司, 郷 康広, 星野 幹雄. 自閉症感受性遺伝子AUT2のマウス海馬歯状回における機能解析. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-1264]
Books (1)：
  • 感覚器官と脳内情報(シリーズ・バイオサイエンスの新世紀12)
    共立出版 2002 ISBN:4320055632
Lectures and oral presentations  (15)：
  • The role of AUTS2 in synaptic organization and the cognitive functions during postnatal brain development
    (2018)
  • Loss of Auts2 induces the defects of synaptic function and cognitive brain functions
    (2018)
  • The role of AUTS2 in synaptic formation and the cognitive brain functions
    (2018)
  • 生後発達期大脳における自閉症感受性遺伝子AUTS2の生理機能の解析
    (第40回日本分子生物学会年会 2017)
  • The role of autism susceptibility gene AUTS2 in the cerebellar Purkinje development.
    (2016)
ｍore...
Education (3)：
  • 2000 - 2004 Osaka University Graduate School of Medicine
  • 1998 - 2000 Tokyo Institute of Technology, Japan Department of Bioscience and Biotechnology
  • 1994 - 1998 Shinshu University Faculty of Textile Science & Technology
Professional career (1)：
  • 医学博士 (大阪大学)
Work history (5)：
  • 2013 - 現在 National Institute of Neuroscience, NCNP, Japan Department of Neurochemistry Section Chief
  • 2012 - 2013 National Institute of Neuroscience, NCNP, Japan Department of Cellular and Biochemistry Postdoctoral fellow
  • 2009 - 2012 National Institute of Neuroscience, NCNP, Japan Department of Cellular and Biochemistry Postdoctoral fellow
  • 2005 - 2009 UT Southwestern Medical Center at Dallas, TX Department of Neuroscience Postdoctoral fellow
  • 2004 - 2005 Osaka University Graduate School of Medicine Department of Neuroscience Postdoctoral fellow
Committee career (1)：
  • 2020/09 - 現在 日本神経化学会 日本神経化学会評議員
Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPAN NEUROSCIENCE SOCIETY
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