Research keywords (2)：
cancer stem cells
Research theme for competitive and other funds (3)：
2010 - 2011 Study of the function of the nuclear protein LDOC1 in the regulation of MDM2-mediated p53 ubiquitination
2008 - 2009 Study on the function of the transcriptional repressor Fbl10 in the regulation of c-Jun
2007 - 2009 Molecular mechanism of tumor cell growth
Kimura MY, Koyama-Nasu R, Yagi R, Nakayama T. A new therapeutic target: the CD69-Myl9 system in immune responses. Seminars in Immunopathology. 2019. 41. 3. 349-358
Endo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata T, Kanuka H, Tumes DJ & Nakayama T. ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis. Nature Metabolism. 2019. 1. 261-275
Mita Y, Kimura MY, Hayashizaki K, Koyama-Nasu R, Ito T, Motohashi S, Okamoto Y, Nakayama T. Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells. International Immunology. 2018. 30. 12. 559-567
Funato K, Hayashi T, Echizen K, Negishi L, Shimizu N, Koyama-Nasu R, Nasu-Nishimura Y, Morishita Y, Tabar V, Todo T, Ino Y, Mukasa A, Saito N, Akiyama T. SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity. EMBO Reports. 2018. 19. 11. e45587
The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun.
(The 21st Naito Conference: Nuclear Dynamics and RNA [I]/26th Summer Symposium in Molecular Biology: Chromatin and Epigenetic Regulation of Transcription 2007)
The critical role of cyclin D2 in glioblastoma stem cells.
The histone deacetylase SIRT2 regulates the cell proliferation and tumorigenicity of glioblastoma cancer stem cells.
(American Association for Cancer Research 102nd Annual Meeting 2011 2011)
The molecular mechanisms of the regulation of Wnt signaling in glioblastoma stem cells
Identification of a novel long non-coding RNA involved in the tumorigenicity of ovarian clear cell carcinoma.
(14th Biennial Meeting of the International Gynecologic Cancer Society 2012)