YASUSHI SHINTANI

シンタニヤスシ | YASUSHI SHINTANI

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/90572983.ja.html

Research field (2)： Respiratory surgery , Cardiovascular surgery

Research keywords (13)：抗癌剤耐性 , 癌幹細胞 , 上皮間葉移行 , TGF , 癌微小環境 , 腫瘍間質 , TGF-b , 肺癌 , 癌間連線維芽細胞 , 肺移植 , 慢性拒絶反応 , IL-6 , Th17

Research theme for competitive and other funds (27)：

2024 - 2027 肺移植後の在宅呼吸機能モニタリング・解析と予測モデル開発:多施設共同研究
2023 - 2027 がん間質FAPI PETイメージングにおける集積の生物学的背景と臨床的意義の解明
2023 - 2026 胸腺上皮性腫瘍の腫瘍間質をターゲットとした治療戦略の探索
2022 - 2025 術中の動画及び音声情報を用いた手術チームパフォーマンスの統合的解明
2022 - 2025 肺癌の間質形成と肺線維化における線維芽細胞を標的とした新規免疫療法の基盤確立

2022 - 2025 肺がんにおける癌関連線維芽細胞の機能解析と新規治療戦略の提案

2022 - 2025 ペリオスチンを基軸とした間質性肺炎合併肺癌に対する包括的治療法の開発

2019 - 2023 Perspective of targeting cancer-associated fibroblasts in non-small-cell lung cancer

2019 - 2022 Regenerating medicine using multilayered tissues with adipose derived stem cell for COPD

2019 - 2022 Development of novel treatment strategy against ischemia reperfusion lung injury after lung transplantation via the inhibition of necroptosis.

2019 - 2022 New Therapeutic Strategy for Lung Cancer with Interstitial Lung Diseases

2017 - 2020 Stem cell based therapy for lung regeneration

2016 - 2019 The mechanism of PD-L1 expression and the clinical significance

2015 - 2018 Perspective of targeting tumor microenvironment in non-small-cell lung cancer

2015 - 2018 New threapeutic strategy for lung transplantation

2015 - 2018 Sustained-release delivery of prostacyclin analogue(ONO-1301) enhances lung regeneration after pnuemonectomy in mice

2014 - 2017 Cell-based therapy in lung regenerative medicine using adipose tissue-derived stem cell and induced pluripotent stem cell

2013 - 2017 New molecular target for lung cancer using PPAR-gamma

2013 - 2016 New surgical strategy for lung cancer based on circulating tumor cells

2013 - 2016 The mechanism of metastasis of circulating tumor cells in non small cell lung cancer

2013 - 2016 The establishment of multimodal therapy of thymic epithelial tumors with podoplanin expression

2012 - 2015 Cytokine receptor dephosphorylation molecules target therapy for rejection after lung transplantation

2012 - 2015 Therapeutic Perspective of Tumor Microenvironment in Non-Small Cell Lung Cancer

2012 - 2015 Lung Regenerative Therapy Using Cell Sheets Releasing Cytokines for COPD Patients

2011 - 2014 Development of novel method to control chronic rejection after lung transplantation using suppression of IL-6 amplifier

2010 - 2011 Therapeutic perspective of tumor microenvironment in non-small-cell lung cancer.

2000 - 非小細胞肺癌におけるTS・DPD発現

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Papers (289)：

Kiyoharu Fukushima, Yuki Matsumoto, Yuko Abe, Kazuki Hashimoto, Daisuke Motooka, Seigo Kitada, Haruko Saito, Sho Komukai, Eriko Fukui, Takayuki Niitsu, et al. Variability of macrolide-resistant profile in Mycobacterium avium complex pulmonary disease. Antimicrobial agents and chemotherapy. 2024. e0121324
Kazuma Sakura, Muneyoshi Kuroyama, Yasushi Shintani, Soichiro Funaki, Shinji Atagi, Yoshihisa Kadota, Kozo Kuribayashi, Takashi Kijima, Takashi Nakano, Toshihiro Nakajima, et al. Dose-escalation, tolerability, and efficacy of intratumoral and subcutaneous injection of hemagglutinating virus of Japan envelope (HVJ-E) against chemotherapy-resistant malignant pleural mesothelioma: a clinical trial. Cancer Immunology, Immunotherapy. 2024. 73. 12
Kazuhiko Hayashi, Hiroshi Ishikawa, Kei Fujiwara, Masataka Nakai, Hitoshi Ono, Yasutoshi Fumimoto, Nobuyuki Tamaki, Shotaro Tatekawa, Takero Hirata, Toru Kimura, et al. Stereotactic Ablative Radiotherapy for Early-stage Lung Cancer in Patients With Left Ventricular Assist Device: A Case Series. Anticancer research. 2024. 44. 9. 4113-4117
Ryuichi Waseda, Hiroyuki Yamamoto, Yasushi Shintani, Toshihiko Sato, Kenji Suzuki, Yoshimasa Maniwa, Yukio Sato, Ichiro Yoshino, Masayuki Chida. Preoperative risk-factors for secondary spontaneous pneumothorax surgery in Japan: a nationwide database study. Surgery today. 2024
Moto Yaga, Kana Hasegawa, Shunya Ikeda, Miwa Matsubara, Takashi Hiroshima, Toru Kimura, Yuya Shirai, Wibowo Tansri, Hirofumi Uehara, Mana Tachikawa, et al. CD98 heavy chain protein is overexpressed in non-small cell lung cancer and is a potential target for CAR T-cell therapy. Scientific reports. 2024. 14. 1. 17917-17917

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MISC (596)：

東口将佳, 福井絵里子, 永田秀樹, 松本智成, 秦明典, 森井英一, 新谷康. 気管支原性嚢胞,肺葉外肺分画症,気管支閉鎖症が併存した1例. 日本呼吸器学会誌. 2024. 13. 3. 126-130
小島史嗣, 分島良, 河北直也, 上田雄一郎, 豊洋次郎, 小林正嗣, 佐藤雅昭, 清水公裕, 新谷康, 滝沢宏光, et al. 日本におけるsublobar切除とマーキング法の現状肺精密縮小手術研究会からの報告. 日本呼吸器外科学会雑誌. 2024. 38. 3. PS5-8
鈴木秀海, 吉野一郎, 新谷康, 四倉正也, 渡辺俊一, 川口知哉, 山本信之, 清家正博, 高橋和久, 高山浩一, et al. 肺癌登録事業報告2024年. 日本呼吸器学会誌. 2024. 13. 増刊. 128-128
井上義一, 澄川裕充, 清水重喜, 香川智子, 馬場智尚, 冨岡洋海, 竹内奈緒子, 武井玲生仁, 山野泰彦, 久瀬雄介, et al. びまん性肺疾患過敏性肺炎線維性過敏性肺炎と膠原病合併例に関する研究第13回大阪呼吸器シンポジウム報告. 日本呼吸器学会誌. 2024. 13. 増刊. 195-195
Y. Morimura, S. Tanaka, K. Matsubara, S. Tanaka, T. Kanou, Y. Yamada, Y. Yutaka, A. Ohsumi, D. Nakajima, M. Hamaji, et al. (78) Indication and Long-Term Outcome of Pediatric Lung Transplantation in Japan; A Multicenter, Retrospective Study. The Journal of Heart and Lung Transplantation. 2023. 42. 4. S44-S45

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Education (2)：

2000 - 2004 大阪大学大学院医学系研究科未来医療開発専攻
1989 - 1995 Osaka University Faculty of Medicine

Work history (2)：

2019/04 - 現在 Osaka University General Thoracic Surgery Professor
2015/09 - 現在 Osaka University

Committee career (1)：

American association for cancer research association member

Awards (6)：

2018/11 - 日本肺癌学会日本肺癌学会篠井・河合賞肺癌微小環境を標的とした肺癌治療の開発
2014/05 - 日本呼吸器外科学会日本呼吸器外科学会賞
2010/03 - 財団法人武田科学振興財団武田科学振興財団医学系研究奨章
2009/12 - 大阪から肺癌をなくす会研究奨励賞
2009/02 - 財団法人大阪対がん協会研究奨励賞

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Association Membership(s) (10)：

日本癌治療学会 , American association for cancer research , 日本視鏡外科学会 , 日本呼吸器外科学会 , 日本胸部外科学会 , 日本癌学会 , 日本消化器外科学会 , 日本肺癌学会 , 日本呼吸器学会 , 日本外科学会

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