Rchr
J-GLOBAL ID:201401062284245206   Update date: Jan. 31, 2024

Shinohara Mito

Shinohara Mito
Affiliation and department:
Research field  (1): Genetics
Research theme for competitive and other funds  (24):
  • 2018 - 2021 Long-term culture of human spermatogonial stem cells
  • 2017 - 2019 Role of testicular somatic cells in regulation of spermatogonial stem cell aging
  • 2015 - 2018 Development of in vitro culture system for expansion of Leydig stem cells
  • 2015 - 2017 長期培養系を用いた精子幹細胞の老化メカニズムの解明
  • 2014 - 2017 Role of CDK inhibitors in self-renewal regulation of spermatogonial stem cell
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Papers (107):
  • Mito Kanatsu-Shinohara, Yusuke Shiromoto, Narumi Ogonuki, Kimiko Inoue, Satoko Hattori, Kento Miura, Naomi Watanabe, Ayumi Hasegawa, Keiji Mochida, Takuya Yamamoto, et al. Intracytoplasmic sperm injection induces transgenerational abnormalities in mice. Journal of Clinical Investigation. 2023. 133. 22
  • Takashi Shinohara, Takuya Yamamoto, Hiroko Morimoto, Yusuke Shiromoto, Mito Kanatsu-Shinohara. Allogeneic offspring produced by induction of PD-L1 in spermatogonial stem cells via self-renewal stimulation. Stem cell reports. 2023. 18. 4. 985-998
  • Takehiro Miyazaki, Mito Kanatsu-Shinohara, Narumi Ogonuki, Shogo Matoba, Atsuo Ogura, Chihiro Yabe-Nishimura, Hongliang Zhang, Yves Pommier, Andreas Trumpp, Takashi Shinohara. Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro. Development (Cambridge, England). 2023
  • Takehiro Miyazaki, Mito Kanatsu-Shinohara, Masatsugu Ema, Takashi Shinohara. Signal regulatory protein alpha is a conserved marker for mouse and rat spermatogonial stem cells. Biology of reproduction. 2023
  • Mito Kanatsu-Shinohara, Jiyoung Lee, Takehiro Miyazaki, Hiroko Morimoto, Takashi Shinohara. Adenovirus-mediated gene delivery restores fertility in congenitally infertile female mice. The Journal of reproduction and development. 2022. 68. 6. 369-376
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MISC (26):
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Lectures and oral presentations  (10):
  • アデノ随伴ウイルスによる卵巣への遺伝子導入
    (【新学術・全能性】領域会議 2021)
  • 精子幹細胞の老化機構の解明
    (京都大学・医薬系研究交流サロン 2020)
  • 睡眠構築の変化が精子形成に及ぼす影響の解析
    (AMED-CREST機能低下 領域会議 2020)
  • 長期培養における精子幹細胞の老化
    (第1回AMED-CREST機能低下・睡眠グループ分科会 2018)
  • 精子を作る幹細胞とその操作技術
    (日本女性科学者の会 60周年記念シンポジウム 2018)
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Awards (3):
  • 2019/09 - Outstanding paper award Reversible inhibition of the blood-testis barrier protein improves stem cell homing in mouse testes
  • 2018/05 - 社団法人日本女性科学者の会 第23回日本女性科学者の会奨励賞 精子幹細胞の自己複製と維持のメカニズムの解明
  • 2007/10 - 日本繁殖生物学会 第100回記念シンポジウム 生殖科学奨励賞受賞 精子幹細胞による遺伝子改変動物の作成
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