Kaneko Takehito

Affiliation and department：

Research field (2)： Laboratory animal science , Biological resource conservation

Research keywords (4)：動物繁殖 , 配偶子保存 , 受精技術 , 野生動物保全

Research theme for competitive and other funds (15)：

2021 - 2024 精管結紮雄を用いない新規人工偽妊娠誘起法の開発および妊娠機能の評価
2020 - 2023 ゲノム・細胞情報に基づく国内希少動物の繁殖促進戦略
2019 - 2023 加齢精子の非コードRNA制御による精神・発達障害の克服
2019 - 2023 Visual properties in rats transuduced newly developed step function opsin
2017 - 2020 Identification of causative genes in a rat model of atopic dermatitis

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Papers (70)：

Hiroyuki Matsuo, Kohei Kawakami, Hiroki Ohara, Takehito Kaneko, Tomoji Mashimo, Takaya Yamada, Toru Nabika. Apolipoprotein E-depletion accelerates arterial fat deposition in the spontaneously hypertensive rat. Experimental animals. 2023
Yuki Numakura, Risa Uemura, Miyuu Tanaka, Takeshi Izawa, Jyoji Yamate, Takashi Kuramoto, Takehito Kaneko, Tomoji Mashimo, Takashi Yamamoto, Tadao Serikawa, et al. PHF24 is expressed in the inhibitory interneurons in rats. Experimental animals. 2021. 70. 1. 137-143
Batbayar Odongoo, Hiroki Ohara, Davis Ngarashi, Takehito Kaneko, Yayoi Kunihiro, Tomoji Mashimo, Toru Nabika. Pathophysiological significance of Stim1 mutation in sympathetic response to stress and cardiovascular phenotypes in SHRSP/Izm: In vivo evaluation by creation of a novel gene knock-in rat using CRISPR/Cas9. Clinical and Experimental Hypertension. 2020. 23. 1-8
Takehito Kaneko, Shungo Tanaka. Improvement of genome editing by electroporation using embryos artificially removed cumulus cells in the oviducts. Biochemical and Biophysical Research Communications. 2020. 527. 1039-1042
Yi-Qiang Liang, Akemi Kakino, Yasunari Matsuzaka, Tomoji Mashimo, Masato Isono, Tomohisa Akamatsu, Hana Shimizu, Michiko Tajima, Takehito Kaneko, Lei Li, et al. LOX-1 (Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) Deletion Has Protective Effects on Stroke in the Genetic Background of Stroke-Prone Spontaneously Hypertensive Rat. Stroke. 2020. 51. 6. 1835-1843

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MISC (32)：

Reproductive technologies for the generation and maintenance of valuable animal strains. 2018. 64. 3. 209-215
Reproductive technologies for the generation and maintenance of valuable animal strains. 2018. 64. 3. 209-215
Kurasaka M, Kaneko T, Suzuki S, Tsukamoto S, Imai H, Minami N. Functional analysis of histone demethylase Kdm5b in mouse preimplantation development. 4th World Congress of Reproductive Biology. 2017
Honda S, Suzuki S, Tsukamoto S, Kaneko T, Imai H, Minami N. The role of SMYD3 in methylation of H3K4 of Hmgpi promoter regions in mouse preimplantation embryos. 4th World Congress of Reproductive Biology. 2017
Hiroyuki Matsuo, Takehito Kaneko, Koichi Fujikawa, Hiroki Ohara, Tomoji Mashimo, Toru Nabika. DEVELOPMENT OF A NEW MODEL FOR COMBINED ATHEROSCLEROSIS AND HYPERTENSION: APOE-KNOCKOUT SPONTANEOUSLY HYPERTENSIVE RAT. ATHEROSCLEROSIS. 2017. 263. E86-E86

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Patents (3)：

Methods for producing transgenic animals
Frozen spermatozoa compositions and uses thereof
エレクトロポレーションを利用した哺乳類の遺伝子改変方法

Books (10)：

Genome Editing in Mouse and Rat by Electroporation
Springer 2017
Genome Editing of Rat
Springer 2017
Genome Editing in Mouse and Rat by Electroporation
Methods in Molecular Biology, Humana Press 2017
Genome Editing of Rat
Methods in Molecular Biology, Humana Press 2017
Creating knockout and knockin rodents using engineered endonucleases via direct embryo injection
Methods in Molecular biology, Humana Press 2015

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Lectures and oral presentations (80)：

マウス・ラット生殖技術の開発とゲノム編集、遺伝資源保存への応用
(基生研セミナー 2018)
遺伝子改変動物作製と系統保存の現状
(岩手医科大学 2018)
NEPA21を用いたエレクトロポレーション法(TAKE法)によるゲノム編集動物作製の現状
(日本実験動物技術者協会総会 2018)
ラットにおける効率的な新規系統作製法の開発に関する研究
(日本繁殖生物学会技術賞受賞講演 2017)
Electroporation increases the efficiency of model creation
(Fifth meeting of the Transgenic Rat ImmunoPhenomic platform 2017)

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Education (2)：

2005 - 熊本大学(医学博士)
- 2000 Kindai University

Work history (4)：

2017/04 - 2024/03 岩手大学大学院理工学研究科准教授
2010/04 - 2017/03 京都大学大学院医学研究科特定講師
2000/04 - 2010/03 熊本大学生命資源研究・支援センター助教
2001/08 - 2003/08 University of Hawaii Institute for Biogenesis Research Visiting Researcher

Awards (9)：

2020 - 日本実験動物学会日本実験動物学会若手優秀賞
2017 - 日本繁殖生物学会技術賞
2015 - 日本獣医学会獣医繁殖学分科会長賞
2014 - 日本実験動物学会奨励賞
2014 - 日本繁殖生物学会大会優秀発表賞

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Association Membership(s) (9)：

野生動物保全繁殖研究会 , 日本畜産学会 , JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE , SOCIETY FOR REPRODUCTION AND DEVELOPMENT , JAPANESE ASSOCIATION FOR EXPERIMENTAL ANIMAL TECHNOLOGISTS , JAPANESE SOCIETY OF ZOO AND WILDLIFE MEDICINE , 九州実験動物研究会 , 関西実験動物研究会 , 東北動物実験研究会

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