Rchr
J-GLOBAL ID：201401069909640685
Update date: Nov. 16, 2024
Fujiwara Takahiro
フジワラ タカヒロ | Fujiwara Takahiro
Affiliation and department：
Job title：
Program-Specific Associate Professor
Homepage URL (1)：
https://kyouindb.iimc.kyoto-u.ac.jp/j/dP8hT
Research field (3)：
Nanobioscience
, Cell biology
, Biophysics
Research keywords (2)：
Function of the clellular plasma membrane
, Single-molecule nanobiology
Research theme for competitive and other funds (16)：
- 2024 - 2027 Unraveling plasma membrane organization based on cooperative regulation by heterogeneous cytoskeletal filaments
- 2021 - 2026 細胞内分子の構造・動態・機能相関を調べるためのクロススケール可視化制御技術の開発
- 2021 - 2025 超速1分子超解像法による、シグナル経路統合を担う液状ナノ共通シグナル基盤の解明
- 2020 - 2023 Direct single-molecule observation of elementary molecular complex formation processes induced by the compartmentalized plasma membrane
- 2018 - 2021 Development of high-speed super-resolution membrane skeleton elasticity mapping and its application to cell motility analysis
- 2016 - 2021 Signal transduction induced by ultra-transient receptor complexes and its regulation by actin skeleton: a single-molecule study
- 2016 - 2019 Dynamic focal adhesion molecular islands as revealed by super-spatiotemporal-resolution single fluorescent-molecule localization microscopy
- 2013 - 2018 Analysis of moisturization mechanism of stratum corneusm
- 2016 - 2017 Diamond NVC for protein analysis
- 2014 - 2017 Site-specific modification of respiratory complex I for single molecule analysis
- 2014 - 2017 Spatio-temporal analysis of extracellular ATP signaling of pancreatic islets
- 2015 - 2017 Unraveling molecular-selective diffusion barrier at the base of primary cilium by developing single-molecule super-resolution microscopy
- 2014 - 2016 Revealing functional integration of small and short-lived molecular complexes by 3-dimensional super-resolved localization microscopy
- 2013 - 2015 Revealing molecular-selective filter mechanism based on diffusion barrier at the base of primary cilium
- 2012 - 2014 Development of high-speed 3-dimensional single-molecule tracking and its application to studies of small and short-lived cell adhesion molecule complexes
- 2009 - 2011 Development of single-molecule tracking using fluorescent silicon nanoparticles and its application to signaling mechanisms in clathrin-coated pits
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Papers (108)：
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Mai Takagi, Ayana Nagatani, Kenichi Kawano, Ayami Hata, Azusa Yokoyama, Koichi Hayashida, Haruka Hoshi, Mao Sakurai, Tsuyoshi Oyama, Yusuke Kuroda, et al. Stable and Minimum Size Solubilization of Membrane Proteins with Cocktails of Phospholipid Analogues. ACS applied materials & interfaces. 2024
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Chuying Zhou, You Kure Wu, Fumiyoshi Ishidate, Takahiro K Fujiwara, Mineko Kengaku. Nesprin-2 coordinates opposing microtubule motors during nuclear migration in neurons. The Journal of cell biology. 2024. 223. 11
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Akihiro Kusumi, Taka A. Tsunoyama, Kenichi G.N. Suzuki, Takahiro K. Fujiwara, Amine Aladag. Transient, nano-scale, liquid-like molecular assemblies coming of age. Current Opinion in Cell Biology. 2024. 89. 102394-102394
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Masahiko Hirano, Yasuo Yonemaru, Satoshi Shimozono, Mayu Sugiyama, Ryoko Ando, Yasushi Okada, Takahiro Fujiwara, Atsushi Miyawaki. StayGold photostability under different illumination modes. Scientific reports. 2024. 14. 1. 5541-5541
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Kenichi Kawano, Yuki Kuzuma, Koichi Yoshio, Kenta Hosokawa, Yuuto Oosugi, Takahiro Fujiwara, Fumiaki Yokoyama, Katsumi Matsuzaki. Extracellular-Vesicle Catch-and-Release Isolation System Using a Net-Charge Invertible Curvature-Sensing Peptide. Analytical chemistry. 2024. 96. 9. 3754-3762
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MISC (29)：
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Takahiro Fujiwara, Akihiro Kusumi. Development of Ultrafast Camera-based Single-Molecule Imaging Unravels Plasma Membrane Structure and Function in Live Cells. 2024. 64. 5. 235-241
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藤原敬宏. 1分子検出蛍光顕微鏡. 先端の分析法 第2版 エヌ・ティー・エス. 2022. 4-3-4. 387-391
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藤原 敬宏. 暗視野観察. 実験医学増刊 生きてるものは全部観る! イメージングの選び方・使い方100+. 2018. 36. 20. 28-29
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楠見明弘, 藤原 敬宏. 光ピンセット. ライフサイエンス 顕微鏡学ハンドブック 朝倉書店. 2018. 123-127
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楠見明弘, 藤原敬宏. 超高速・超解像1蛍光分子局在顕微鏡法. 日本免疫学会ニュースレター. 2014. 23. 1. 12-12
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Lectures and oral presentations (70)：
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生体膜構造の超解像観察が拓く新しい世界
(日本化学会 第14回 CSJ化学フェスタ2024 テーマ企画「細胞外小胞の新しい世界~細胞からのメッセージとその活用~」 2024)
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超高速1蛍光分子観察による接着斑メゾ構造分子動態の解明
(定量生物学の会 第11回年会 セッション1 「時間と空間の限界を突破する」 2024)
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Mesoscopic architecture and molecular dynamics in focal adhesions as revealed by ultrafast single-molecule imaging
(第61回日本生物物理学会年会 シンポジウム3SEA「細胞のメゾ構造体の形成と機能の機構:先端イメジング法による解明」 2023)
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Mesoscopic architecture and molecular dynamics in focal adhesions as revealed by ultrafast single-molecule imaging
(The East Asia Single Molecule Biology Symposium 2023 (EASMB 2023) 2023)
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Unraveling mesoscopic organization of the plasma membrane by ultrafast single fluorescent-molecule tracking and localization microscopy
(NanoLSI Open Seminar at NanoLSI, Kanazawa University 2021)
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Education (4)：
- 1997 - 1998 Nagoya University Graduate School of Science
- 1995 - 1998 The University of Tokyo Graduate School of Arts and Sciences Department of Life Sciences
- 1993 - 1995 The University of Tokyo Graduate School of Arts and Sciences Department of Life Sciences
- 1988 - 1993 Kyoto University Faculty of Science
Professional career (1)：
- D.Sc. (Nagoya University)
Work history (10)：
- 2017/04 - 現在 Kyoto University Bioanalysis Unit, Analysis Center, Institute for Integrated Cell-Material Sciences, KUIAS Unit Leader
- 2017/04 - 現在 Kyoto University KUIAS, Institute for Integrated Cell-Material Sciences Program-Specific Associate Professor
- 2015/05 - 2017/03 Kyoto University Institute for Integrated Cell-Material Sciences Program-Specific Research Center Associate Professor
- 2013/04 - 2017/03 Kyoto University Center for Meso-Bio Single Molecule Imaging, Institute for Integrated Cell-Material Sciences Deputy Director
- 2010/12 - 2015/04 Kyoto University Institute for Integrated Cell-Material Sciences Program-Specific Research Center Senior Lecturer
- 2008/04 - 2010/11 Kyoto University Institute for Integrated Cell-Material Sciences Research Assistant Professor
- 2005/04 - 2010/03 Kyoto University Institute for Frontier Medical Sciences Research Assistant Professor
- 2005/04 - 2010/03 ICORP, JST Research Fellow
- 2003/10 - 2005/03 SORST, JST Research Fellow
- 1998/10 - 2003/09 ERATO, JST Research Fellow
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Association Membership(s) (2)：
Biophysical Society
, The Biophysical Society of Japan
