Rchr
J-GLOBAL ID:201401070427719088   Update date: May. 01, 2024

Chiba Yoko

チバ ヨウコ | Chiba Yoko
Affiliation and department:
Job title: Senior Scientist
Other affiliations (1):
  • University of Tsukuba  Associate professor
Homepage URL  (1): https://kaken.nii.ac.jp/d/r/70638981.ja.html
Research field  (1): Applied biochemistry
Research keywords  (4): 応用微生物学 ,  microbiology ,  evolution ,  metabolic biochemistry
Research theme for competitive and other funds  (10):
  • 2023 - 2027 アーキアの新規セリン生合成経路同定を通じた中央代謝進化の解明
  • 2023 - 2025 微生物におけるCO同化経路の特定
  • 2019 - 2023 フォルニカータ生物群におけるミトコンドリア関連オルガネラの機能進化の解明
  • 2019 - 2023 TCA回路の多様性とその起源の解明
  • 2020 - 2023 酵素のKm値再考察:最適値を決める因子の探索
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Papers (20):
  • Yoko Chiba, Hideshi Ooka, Marie E Wintzer, Nao Tsunematsu, Toshihiko Nogawa, Takehiro Suzuki, Naoshi Dohmae, Ryuhei Nakamura. Rationalizing the Influence of the Binding Affinity on the Activity of Phosphoserine Phosphatases. Angewandte Chemie (International ed. in English). 2024. 63. 13. e202318635
  • Hideshi Ooka, Yoko Chiba, Ryuhei Nakamura. Thermodynamic principle to enhance enzymatic activity using the substrate affinity. Nature communications. 2023. 14. 1. 4860-4860
  • Yoko Chiba, Hideshi Ooka, Marie Wintzer, Nao Tsunematsu, Takehiro Suzuki, Naoshi Dohmae, Ryuhei Nakamura. Diverse Phosphoserine Phosphatases Exhibit Maximum Activity at an Intermediate Binding Affinity in Accord with the Sabatier Principle of Catalysis. 2023
  • Hideshi Ooka, Yoko Chiba, Ryuhei Nakamura. Universal Design Principle to Enhance Enzymatic Activity using the Substrate Affinity. bioRxiv. 2023
  • Marie Wintzer, Ryuhei Nakamura, Yoko Chiba. Characterization of a Non-Classic Type Phosphoserine Phosphatase Homolog in Thermodesulfidibacter takaii, a Thermophilic, Autotrophic Bacterium in the Phylum Aquificae. FASEB JOURNAL. 2021. 35
more...
MISC (7):
  • 千葉洋子. セリン生合成酵素と酵素の動力学パラメータの多様性に関する発見と考察. 酵素工学ニュース. 2021. 86. 8-12
  • 千葉洋子. アミノ酸生合成とCO2固定経路の密接な関係 グリーンバイオケミストリーから生命進化まで. 化学と生物. 2021. 59. 9. 458-463
  • 千葉 洋子. バイオ系のキャリアデザイン 効率的ではないかもしれないが満足度は高いこれまで. 生物工学会誌. 2017. 95. 9. 557-559
  • Chiba Yoko, Kamikawa Ryoma, Tsukui Kumiko, Nakano Yumiko, Nozaki Tomoyoshi. Identification and characterization of novel PEP carboxykinase from Entamoeba histolytica. 2015
  • Chiba Yoko, Kamikawa Ryoma, Nozaki Tomoyoshi. Identification and characterization of a lost central metabolic enzyme, phosphoenolpyruvate carboxykinase. 2015
more...
Books (1):
  • 独立栄養微生物によるCO2資源化技術
    シーエムシー出版 2023 ISBN:9784781317564
Lectures and oral presentations  (13):
  • 独立栄養性細菌Thermodesulfatator indicusが有する未知のセリン生合成経路の探索
    (日本農芸化学会2024年度大会 2024)
  • 新規CO資化性微生物の探索-好熱性水素細菌Hydrogenobacter thermophilusのCO耐性および資化性の検証
    (日本農芸化学会2024年度大会 2024)
  • Exploring a novel glycine biosynthesis pathway in Thermodesulfatator indicus, a thermophilic sulfate-reducing bacterium using isotopomer analysis.
    (The 36th JSME & The 13th ASME 2023)
  • Directionality of CO2 fixation pathways in the presence of other carbon sources
    (The 36th JSME & The 13th ASME 2023)
  • Mathematical Theory to Maximize Enzymatic Activity Under Thermodynamic Constraints
    (10th International Congress on Industrial and Applied Mathematics 2023)
more...
Professional career (1):
  • 博士(農学) (東京大学)
Work history (11):
  • 2021/10 - 現在 University of Tsukuba Faculty of Life and Environmental Sciences Associate professor
  • 2021/06 - 現在 RIKEN RIKEN Center for Sustainable Resource Science Senior Scientist
  • 2022/10 - 2022/10 Max Planck Institute Terrestrial microbiology Guest scientist
  • 2019/04 - 2021/05 RIKEN Center for Sustainable Resource Science (CSRS) Research Scientist
  • 2016/04 - 2019/03 海洋研究開発機構 深海・地殻内生物圏研究分野 ポストドクトラル研究員
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Awards (8):
  • 2024/04 - 日本農芸化学会 2024年度大会 トピックス賞 新規CO資化性微生物の探索-好熱性水素細菌Hydrogenobacter thermophilusのCO耐性および資化性の検証
  • 2024/04 - RIKEN Center for Sustainable Resource Science CSRS Incentive Award Thermodynamic principle to enhance enzymatic activity using the substrate affinity
  • 2020/03 - Japan Society for Bioscience, Biotechnology, and Agrochemistry JSBBA Award for Young Women Scientists
  • 2017/03 - The Japan Society for Bioscience, Biotechnology, and Agrochemistry Award for Excellence to Authors Publishing in Bioscience, Biotechnology, and Biochemistry in 2016 Discovery of an intermolecular disulfide bond required for the thermostability of a heterodimeric protein from the thermophile Hydrogenobacter thermophilus
  • 2016/10 - Japan Bioindustry Association Fermentation and Metabolism Research Award Discovery of novel enzymes: Diversity and evolutionary history of proteins involved in central metabolism
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