Research theme for competitive and other funds (5)：
2022 - 2025 CRISPR screen to identify novel molecular mechanisms of HIV-1 latency
2019 - 2022 Transcriptome analysis of HIV-1 latently infected cells
2019 - 2022 APOBEC3B-induced genome mutations and its contribution to clonal evolution in cancers
2018 - 2021 Comprehensive enhancer analysis and molecular pathogenesis of leukemia using our novel technology
2016 - 2019 Role of A3G acetylation and Vif/HDAC3 complex in HIV-1 infection
Papers (70)：
Hiroki Futatsusako, Rina Hashimoto, Masaki Yamamoto, Jumpei Ito, Yasufumi Matsumura, Hajime Yoshifuji, Kotaro Shirakawa, Akifumi Takaori-Kondo, Kei Sato, Miki Nagao, et al. Longitudinal analysis of genomic mutations in SARS-CoV-2 isolates from persistent COVID-19 patient. iScience. 2024. 27. 5. 109597-109597
Yuuka Masuda, Hesham Nasser, Jiri Zahradnik, Shuya Mitoma, Ryo Shimizu, Kayoko Nagata, Akifumi Takaori-Kondo, Gideon Schreiber, Kotaro Shirakawa, Akatsuki Saito, et al. Characterization of the evolutionary and virological aspects of mutations in the receptor binding motif of the SARS-CoV-2 spike protein. Frontiers in Virology. 2023. 3
Shigeru Fujita, Yusuke Kosugi, Izumi Kimura, Kenzo Tokunaga, Jumpei Ito, Kei Sato, Keita Matsuno, Naganori Nao, Hirofumi Sawa, Shinya Tanaka, et al. Determination of the factors responsible for the tropism of SARS-CoV-2-related bat coronaviruses to Rhinolophus bat ACE2. Journal of Virology. 2023. 97. 10
Tomokazu Tamura, Hayato Ito, Shiho Torii, Lei Wang, Rigel Suzuki, Shuhei Tusjino, Akifumi Kamiyama, Yoshitaka Oda, Yuhei Morioka, Saori Suzuki, et al. Akaluc bioluminescence offers superior sensitivity to trackin vivodynamics of SARS-CoV-2 infection. 2023
Izumi Kimura, Daichi Yamasoba, Hesham Nasser, Hayato Ito, Jiri Zahradnik, Jiaqi Wu, Shigeru Fujita, Keiya Uriu, Jiei Sasaki, Tomokazu Tamura, et al. Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics. Journal of virology. 2023. e0101123
Tadahiko Matsumoto, Kotaro Shirakawa, Hiroyuki Matsui, Hiroyuki Yamazaki, Yasuhiro Kazuma, Anamaria Daniela Sarca, Hirofumi Fukuda, Wataru Maruyama, Akifumi Takaori-Kondo. PKA-Mediated Phosphorylation of APOBEC3B Suppresses Its DNA Mutagenic Potential in Myeloma Cells. BLOOD. 2016. 128. 22
Hisashi Takei, Masanori Fujii, Sohei Nakayama, Ikei Kobayashi, Keisuke Shindo, Kotaro Shirakawa, Akifumi Takaori-Kondo, Susumu Kobayashi. Alternative Splicing of APOBEC3D Generates Functional Diversity and Its Role As a DNA Mutator. BLOOD. 2016. 128. 22
