SUZUKI Ayumu

スズキアユム | SUZUKI Ayumu

Affiliation and department：
Job title： Lecturer

Research field (1)： Developmental biology

Research theme for competitive and other funds (10)：

2023 - 2026 Elucidation of the molecular mechanisms by which germ cells inactivate the function of polycomb that acts against meiotic onset
2023 - 2026 非生殖細胞での減数分裂関連遺伝子の異所的な発現を抑制するための分子基盤の解明
2021 - 2024 哺乳類生殖細胞の減数分裂開始機構の解明
2021 - 2024 哺乳類生殖細胞の減数分裂開始機構の解明
2019 - 2022 Understanding of the molecular bases of liberation of germ cells from Max-dependent suppression of meiotic onset

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Papers (30)：

Takehiro Nogi, Kousuke Uranishi, Ayumu Suzuki, Masataka Hirasaki, Tina Nakamura, Tomiei Kazama, Hiroshi Nagasaka, Akihiko Okuda, Tsutomu Mieda. Similarity and dissimilarity in alterations of the gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane. PloS one. 2024. 19. 3. e0298264
Yuka Kitamura, Ayumu Suzuki, Kousuke Uranishi, Masazumi Nishimoto, Seiya Mizuno, Satoru Takahashi, Akihiko Okuda. Alternative splicing for germ cell-specific Mga transcript can be eliminated without compromising mouse viability or fertility. Development, growth & differentiation. 2022. 64. 7. 409-416
Kentaro Mochizuki, Jafar Sharif, Kenjiro Shirane, Kousuke Uranishi, Aaron B Bogutz, Sanne M Janssen, Ayumu Suzuki, Akihiko Okuda, Haruhiko Koseki, Matthew C Lorincz. Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing. Nature communications. 2021. 12. 1. 7020-7020
Kousuke Uranishi, Masataka Hirasaki, Yuka Kitamura, Yosuke Mizuno, Masazumi Nishimoto, Ayumu Suzuki, Akihiko Okuda. Two DNA binding domains of MGA act in combination to suppress ectopic activation of meiosis-related genes in mouse embryonic stem cells. Stem cells (Dayton, Ohio). 2021
Yuka Kitamura, Kousuke Uranishi, Masataka Hirasaki, Masazumi Nishimoto, Ayumu Suzuki, Akihiko Okuda. Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1. Scientific reports. 2021. 11. 1. 9737-9737

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MISC (4)：

西本正純, 西本正純, 浦西洸介, 浅賀正充, 鈴木歩, 水野洋介, 平崎正孝, 奥田晶彦. Yapの異常な活性化による形質転換はYap/TEAD複合体によるcMyc遺伝子の転写亢進による. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
平崎正孝, 鈴木歩, 浦西洸介, 浅賀正充, 西本正純, 奥田晶彦. Mbd3/NuRD転写抑制複合体によるES細胞への分化多能性賦与機構の解明. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
西本正純, 鈴木歩, 浦西洸介, 浅賀正充, 平崎正孝, 奥田晶彦. Yapによる細胞の形質転換におけるmiR29を介さない経路の重要性. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
鈴木歩, 平崎正孝, 浅賀正充, 浦西洸介, 西本正純, 奥田晶彦. 体細胞分裂から減数分裂への切り替えを制御するMyc/Max/Mgaネットワーク. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th

Lectures and oral presentations (31)：

MAX は始源生殖細胞で減数分裂遺伝子を抑制する
(第3回有性生殖研究会「生殖の多様性」 2023)
MAX regulates the meiosis-related genes in mouse germ cells
(2022)
Molecular mechanisms for the initiation of meiosis in mouse germ cells
(The 44th Annual Meeting of the Molecular Biology Society of Japan 2021)
Mga inhibits meiotic initiation by regulating Meiosin-Stra8 signaling through the bHLHZ region.
(2021)
Generation of meiotic germ cell-specific Mga splice variant for promoting meiotic onset via inactivation of non-canonical PRC1
(第43回日本分子生物学会年会 2020)

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Education (1)：

Professional career (1)：

Awards (2)：

Association Membership(s) (1)：

分子生物学会

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