Hirashima Tsuyoshi

ヒラシマツヨシ | Hirashima Tsuyoshi

Affiliation and department：
Job title： Principal Investigator
Other affiliations (1)：

National University of Singapore Department of Physiology Assistant Professor

Homepage URL (1)： https://sites.google.com/view/hirashima-group/home

Research field (4)： Cell biology , Biophysics , Morphology, anatomy , Developmental biology

Research keywords (7)： Reproduction , Imaging , Systems Biology , Mechanobiology , Mathematical Modeling , Development , Tissue morphogenesis

Research theme for competitive and other funds (12)：

2019 - 2023 曲率に対する力学応答システムによる分岐形態形成
2021 - 2022 Biophysical understanding of cell competition mechanisms for multicellular autonomy
2021 - 2022 精子アクティブマターによる生体内集団動態の物理機構
2019 - 2022 Collective cell migration by activation wave of growth factor signal transduction cascade
2021 - 2022 Understanding multicellular autonomy by competitive cell-cell communications

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Papers (46)：

Tsuyoshi Hirashima, Sound WP, Taichi Noda. Collective sperm movement in mammalian reproductive tracts. 2024
Kosuke Mizuno, Tsuyoshi Hirashima, Satoshi Toda. Robust tissue pattern formation by coupling morphogen signal and cell adhesion. EMBO Reports. 2024
Chaoyu Fu, Florian Dilasser, Shao-Zhen Lin, Marc Karnat, Aditya Arora, Harini Rajendiran, Hui Ting Ong, Nai Mui Hoon Brenda, Sound Wai Phow, Tsuyoshi Hirashima, et al. Regulation of intercellular viscosity by E-cadherin-dependent phosphorylation of EGFR in collective cell migration. Proceedings of the National Academy of Sciences. 2024
Tsuyoshi Hirashima, Michiyuki Matsuda. ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue. Current Biology. 2024
Ankita Nitin Nayak, Tsuyoshi Hirashima. Tug-of-war via ERK signaling pathway for tissue organization - ERK activation to force generation. Current opinion in cell biology. 2023. 85. 102249-102249

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MISC (23)：

Paul Trevorrow, Tsuyoshi Hirashima. Meet our editorial board members: An interview with Tsuyoshi Hirashima, National University of Singapore. Biology of the Cell. 2024
平島剛志. シンガポールMBIに飛び込んでみた. 羊土社. 2024
日野直也, 平島剛志. 力学-生化学シグナルの時空間パターン形成と集団遊走. 生物物理. 2024. 64. 2
平島剛志. 巻頭言:スタンダード. 日本細胞生物学会誌. 2023
平島剛志. 新しい研究室の紹介【日本メカノバイオロジー学会】会誌 Vol.2 -2023. 7. 30-. 日本メカノバイオロジー学会誌. 2023

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Lectures and oral presentations (32)：

ERK活性を介したメカノ・ケミカルフィードバック制御による肺上皮の分岐形態形成
(第9回定量生物の会年会 2019)
Adaptive movement of endothelial cells controlled via physical interaction with an developing epithelial tube
(京都大学医学研究科発生・細胞生物・システム生物学コース 2018)
ERK活性を介した細胞集団遊走の数理モデル
(第3回日本メカノバイオロジー学会年会 2018)
Intercellular mechanical wave via intracellular ERK activation during collective cell migration -- experiments and modeling
(Frontline in DevelopmentalBiology 2018)
シグナル活性のライブイメージングと多細胞運動のコンピュテーショナルモデル
(第15回生物数学の理論とその応用-次世代の数理科学への展開- 2018)

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Education (3)：

2008 - 2011 Kyushu University Graduate School of Systems Life Sciences
2006 - 2008 Kyushu University Faculty of Science Department of Biology
2002 - 2006 Kyushu University Faculty of Science Department of Biology

Professional career (1)：

Ph. D. (Kyushu University)

Work history (11)：

2022/06 - 現在 National University of Singapore Department of Physiology, Yong Loo Lin School of Medicine Assistant Professor
2022/06 - 現在 National University of Singapore Mechanobiology Institute Principal Investigator
2021/01 - 2022/06 Kyoto University The Hakubi Center/Graduate School of Biostudies Program-specific Associate Professor
2019/10 - 2023/03 JST PRESTO researcher
2017/04 - 2020/12 Kyoto University Graduate School of Medicine Senior lLcturer

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Committee career (8)：

2024 - 現在 Biology of the Cell Editorial Board
2022 - 現在 Journal of Theoretical Biology Editorial Board
2021/01 - 現在 JSCB Editorial Board
2018/06 - 現在 JSCB Delegate
2021/01 - 2023/12 BSJ expert advisor "C27 Development"

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Awards (3)：

2024/04 - Japanese Society of Developmental Biologists JSDB Frontiers Prize
2023/04 - 文部科学省若手科学者賞多細胞組織の形態形成に関するメカノバイオロジーの研究
2017/09 - The Biophysical Society of Japan The BSJ Award for Young Researchers

Association Membership(s) (5)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY FOR CELL BIOLOGY , THE BIOPHYSICAL SOCIETY OF JAPAN , THE JAPANESE SOCIETY FOR MATHEATICAL BIOLOGY , JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS

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