Ando Hitoshi

アンドウヒトシ | Ando Hitoshi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://saiboubunshikinoh.wixsite.com/home

Research field (2)： Pharmacology , Metabolism and endocrinology

Research keywords (10)： lifestyle-related diseases , circadian rhythm , biological clock , pharmacology , chronotherapy , chronopharmacology , endocrinology , clinical pharmacology , drug interaction , genetic polymorphism

Research theme for competitive and other funds (25)：

2023 - 2027 Frailty prevention: circadian clock and mitochondrial functions
2023 - 2026 朝の楽しい感覚統合と体幹トレーニングが小学生の集中力と学力に与える影響
2022 - 2025 Application of chronobiology to uterine leiomyomas and infertility
2021 - 2025 思春期の欠食とダイエットで性差をもって“リプログラミング”される食欲と代謝効率
2021 - 2024 Elucidation of pathophysiology and treatment strategies of peripheral clock disruption

2020 - 2024 概日リズムに基づく妊娠・産褥期セルフケアプログラムの開発-光と食による制御の検討

2020 - 2022 Analysis of the mechanisms of induction of cancer initiation/progression by abnormal peripheral circadian rhythm using cancer mouse models

2019 - 2022 概日リズムによる子宮収縮制御機構に着目した産婦人科疾患予防法の探索

2019 - 2022 Comprehensive analysis of female reproductive dysfunction induced by clock gene memory due to asynchronous feeding rhythm

2018 - 2021 Elucidation of rhythm formation mechanism and treatment strategies of thermogenesis in brown adipocytes

2018 - 2021 概日時計の乱れが誘発する若年女性の生殖機能障害の実態とその機序の解析ー朝食欠食とダイエットに着目してー

2016 - 2019 Development of chrono-exercise programs for sarcopenia prevention

2015 - 2018 Elucidation of pathophysiology and treatment strategies of peripheral clock disruption

2013 - 2017 Development of a method to attenuate the adverse effect of anti-arrhythmic bepridil

2012 - 2015 Development of pharmacological therapy targeting peripheral circadian clocks for treatment of type 2 diabetes

2014 - 2014 トキシコゲノミクス手法を用いた薬物安全性臨床バイオマーカーの開発

2011 - 2013 新たな生活習慣病治療法の開発に向けた末梢体内時計制御機構の解明

2010 - 2012 2型糖尿病における末梢体内時計障害の機序解明と治療法の開発

2009 - 2011 トキシコゲノミクス研究の臨床への展開

2009 - 2011 骨粗鬆症治療薬の時間治療の試み

2009 - 2010 骨粗鬆症治療薬の有害反応を軽減する時間治療の試み

2009 - 2010 Evaluation of the pathophysiological significance of peripheral clocks and the development of methods of controlling them

2008 - 2009 体内時計機能障害と関連する生活習慣病の病態解析

2006 - 2007 末梢血中単核球における時計遺伝子発現を指標とした包括的2型糖尿病治療法の確立

2003 - 2005 新規トランスポーターATP-Binding Cassette A8の生理的および病態的役割の解明とその応用

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Papers (165)：

Kotomi Miura, Jun-Ichi Morishige, Jotaro Abe, Pingping Xu, Yifan Shi, Zheng Jing, Naoto Nagata, Ryo Miyazaki, Naoki Sakane, Michihiro Mieda, et al. Imeglimin profoundly affects the circadian clock in mouse embryonic fibroblasts. Journal of pharmacological sciences. 2023. 153. 4. 215-220
Saori Sako, Yumie Takeshita, Hiroaki Takayama, Hisanori Goto, Yujiro Nakano, Hitoshi Ando, Hiromasa Tsujiguchi, Tatsuya Yamashita, Kuniaki Arai, Shuichi Kaneko, et al. Trajectories of Liver Fibrosis and Gene Expression Profiles in Nonalcoholic Fatty Liver Disease Associated With Diabetes. Diabetes. 2023. 72. 9. 1297-1306
Jun-ichi Morishige, Kazuaki Yoshioka, Hiroki Nakata, Kazuhiro Ishimaru, Naoto Nagata, Tamotsu Tanaka, Yoh Takuwa, Hitoshi Ando. Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes. Journal of Lipid Research. 2023. 100450-100450
Ryo Miyazaki, Takafumi Abe, Naoki Sakane, Hitoshi Ando, Shozo Yano, Kenta Okuyama, Minoru Isomura, Masayuki Yamasaki, Toru Nabika. Associations between dairy consumption and the physical function in Japanese community-dwelling older adults: The Shimane CoHRE study. Geriatric Nursing. 2023. 53. 19-24
Satoshi Nomura, Takashi Hosono, Masanori Ono, Takiko Daikoku, Michihiro Mieda, Kyosuke Kagami, Takashi Iizuka, Yuchen Chen, Yifan Shi, Jun-Ichi Morishige, et al. Desynchronization between food intake and light stimulations induces uterine clock quiescence in female mice. The Journal of nutrition. 2023. 153. 8. 2283-2290

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MISC (220)：

Masanori Ono, Natsumi Toyoda, Takashi Hosono, Kyosuke Kagami, Jumpei Terakawa, Tomoko Fujiwara, Mieda Michihiro, Hitoshi Ando, Hiroshi Fujiwara, Takiko Daikoku. UTERINE-SPECIFIC BMAL1 DELETION DISRUPTS MATERNAL NEOVASCULARIZATION DURING DECIDUALIZATION/PLACENTATION AND LEADS TO MISCARRIAGE DEATH. PLACENTA. 2021. 114. 141-142
小野政徳, 小野政徳, 豊田夏美, 細野隆, 鏡京介, 寺川純平, 藤原智子, 三枝理博, 安藤仁, 藤原浩, et al. 子宮特異的Bmal1欠損は脱落膜および胎盤における母体側の血管新生を抑制し流死産を誘発する. 日本絨毛性疾患研究会・日本胎盤学会学術集会プログラム・抄録集. 2021. 39th-29th
迫佐央理, 竹下有美枝, 安藤仁, 金森岳広, 石井清朗, 辻口博聖, 水腰英四郎, 山下竜也, 荒井邦明, 本多政夫, et al. NAFLD患者の肝炎症進展因子としての高血糖の意義-連続肝生検による検討. 糖尿病(Web). 2020. 63. Suppl
安藤仁. 生体リズムを考慮した2型糖尿病治療. 大宮医師会報. 2019. 764. 628-630
迫佐央理, 竹下有美枝, 安藤仁, 御簾博文, 辻口博聖, 中村裕之, 原田憲一, 金子周一, 篁俊成. 非アルコール性脂肪性肝疾患(NAFLD)の連続肝生検real-world data 高血糖の肝線維化への寄与. 糖尿病. 2019. 62. Suppl.1. S-155

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Books (32)：

類似薬の使い分け : 症状に合った薬の選び方とその根拠がわかる第3版
羊土社 2021 ISBN:9784758118897
今日の治療指針 2021年版
医学書院 2021 ISBN:9784260042833
循環器診療がわかる現場の教科書 : 診るロジックと薬の使い方
じほう 2020 ISBN:9784840753166
エース薬理学
南山堂 2020 ISBN:9784525140717
今日の治療指針 2020年版
医学書院 2020 ISBN:4260107704

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Professional career (1)：

MD, PhD (Kanazawa University)

Work history (4)：

2016/03 - 現在 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
2009/02 - 2016/02 Jichi Medical University School of Medicine
2008/03 - 2009/01 Jichi Medical University School of Medicine
2007/04 - 2008/02 Kanazawa University

Committee career (5)：

2020/12 - 現在日本臨床薬理学会監事
2019 - 現在日本薬理学会学術評議員
2012/04 - 現在日本内分泌学会評議員
2008/12 - 現在日本臨床薬理学会社員(評議員)
- 現在日本時間生物学会評議員

Awards (3)：

2013 - The Japan Society of Clinical Pharmacology and Therapeutics Japan Research Foundation for Clinical Pharmacology Young Researcher's Award
2011 - Japan Research Foundation for Clinical Pharmacology Grand prize
2011 - Japanese Society for Chronobiology Young Researcher's Award

Association Membership(s) (6)：

THE JAPANESE PHARMACOLOGICAL SOCIETY , JAPANESE SOCIETY FOR CHRONOBIOLOGY , THE JAPAN DIABETES SOCIETY , THE JAPAN ENDOCRINE SOCIETY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , THE JAPANESE SOCIETY OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

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