Rchr
J-GLOBAL ID:201401084829806956
Update date: Aug. 30, 2024
Masayuki Takahashi
タカハシ マサユキ | Masayuki Takahashi
Affiliation and department:
Job title:
Assistant Professor
Research field (2):
Pharmaceuticals - chemistry and drug development
, Molecular biology
Research keywords (4):
RNautophagy
, gymnosis
, tRNase ZL
, sgRNA
Research theme for competitive and other funds (5):
- 2018 - 現在 Gymnosis関連分子とメカニズムの解明
- 2020 - 新規gymnosis関連分子Ly6aの解析とメカニズムの解明
- 2018 - 2018 Gymnosisの関連分子とメカニズムの解明
- 2015 - 2017 Elucidation of the uptake of single-stranded oligonucleotides into living cells
- 2011 - 2014 多発性骨髄腫治療用sgRNA薬の開発
Papers (21):
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Yuuki Fujiwara, Kazuki Oroku, Yinping Zhou, Masayuki Takahashi, Taiichi Katayama, Keiji Wada, Nobuyuki Tsutsumi, Tetsuo Sato, Tomohiro Kabuta. Expression of RNautophagy/DNautophagy-related genes is regulated under control of an innate immune receptor. RNA Biology. 2024. 21. 1. 1-9
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Mineaki Seki, Akihiko Komuro, Tatsuya Ishikawa, Masayuki Takahashi, Masayuki Nashimoto. Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus. Biochemical and Biophysical Research Communications. 2022
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Mineaki Seki, Akihiko Komuro, Masayuki Takahashi, Masayuki Nashimoto. Transcription from the proximal promoter of ELAC1, a gene for tRNA repair, is upregulated by interferons. Biochemical and Biophysical Research Communications. 2021. 583. 31. 162-168
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Masayuki Takahashi, Mineaki Seki, Masayuki Nashimoto, Tomohiro Kabuta. Perturbing the Normal Level of SIDT1 Suppresses the Naked ASO Effect. Journal of Nucleic Acids. 2021. 2021(Article ID 2458470. https://doi.org/10.1155/2021/2458470
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Masayuki Takahashi, Mineaki Seki, Masayuki Nashimoto. A naked antisense oligonucleotide with phosphorothioate linkages is taken up intracellularly more efficiently but functions less effectively. Biochem Biophys Res Commun. 2021. 573. 8. 140-144
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Lectures and oral presentations (6):
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我々独自の核酸医薬開発研究と基礎研究について
(日本生化学若手の会 北陸支部主催 「春の創薬セミナー」 2023)
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Mechanism of the uptake of naked single-stranded oligonucleotides into living cells
(The 34 th Annual Meeting of the Japanese Society for the Study of Xenobiotics in Tsukuba 2019)
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Gymnosis関連分子とメカニズムの解明
(第22回 バイオ治療法研究会学術集会 2018)
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裸の1本鎖オリゴの細胞内への取り込みメカニズム
(第 17 回日本RNA学会年会 2015)
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ヒトの血漿、末梢血単核細胞、培養細胞株由来のtRNase ZLをガイドする小さなRNA
(第56回新潟生化学懇話会 2015)
more...
Education (4):
- 2011 - 2014 Niigata University of Pharmacy and Applied Life Sciences
- 2009 - 2011 Niigata University of Pharmacy and Applied Life Sciences
- 2006 - 2009 Niigata University of Pharmacy and Applied Life Sciences
- 2003 - 2006 新潟県立三条高等学校 普通科
Professional career (3):
- 博士(応用生命科学) (新潟薬科大学大学院)
- 修士(応用生命科学) (新潟薬科大学大学院)
- 学士(応用生命科学) (新潟薬科大学)
Work history (9):
- 2024/08 - 現在 Niigata University of Pharmacy and Medical and Life Sciences Assistant Professor
- 2023/04 - 現在 Niigata University of Pharmacy and Applied Life Sciences
- 2018/07 - 2023/03 Niigata University of Pharmacy and Applied Life Sciences Research Institute for Healthy Living
- 2018/04 - 2018/06 Special researcher of the Japan Society for the Promotion of Science
- 2016/10 - 2018/03 Researcher
- 2015/09 - 2016/09 Assistant Professor
- 2014/06 - 2015/08 Researcher
- 2014/04 - 2014/05 Researcher
- 2011/04 - 2014/03 Special researcher of the Japan Society for the Promotion of Science
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Awards (6):
Association Membership(s) (1):
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