Masayuki Takahashi

タカハシマサユキ | Masayuki Takahashi

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Pharmaceuticals - chemistry and drug development , Molecular biology

Research keywords (4)： RNautophagy , gymnosis , tRNase ZL , sgRNA

Research theme for competitive and other funds (5)：

Papers (20)：

Mineaki Seki, Akihiko Komuro, Tatsuya Ishikawa, Masayuki Takahashi, Masayuki Nashimoto. Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus. Biochemical and Biophysical Research Communications. 2022
Mineaki Seki, Akihiko Komuro, Masayuki Takahashi, Masayuki Nashimoto. Transcription from the proximal promoter of ELAC1, a gene for tRNA repair, is upregulated by interferons. Biochemical and Biophysical Research Communications. 2021. 583. 31. 162-168
Masayuki Takahashi, Mineaki Seki, Masayuki Nashimoto, Tomohiro Kabuta. Perturbing the Normal Level of SIDT1 Suppresses the Naked ASO Effect. Journal of Nucleic Acids. 2021. 2021(Article ID 2458470. https://doi.org/10.1155/2021/2458470
Masayuki Takahashi, Mineaki Seki, Masayuki Nashimoto. A naked antisense oligonucleotide with phosphorothioate linkages is taken up intracellularly more efficiently but functions less effectively. Biochem Biophys Res Commun. 2021. 573. 8. 140-144
Tadasuke Nozaki*, Masayuki Takahashi*, Tatsuya Ishikawa*, Arisa Haino, Mineaki Seki, Hidetomo Kikuchi, Bo Yuan, Masayuki Nashimoto (* first equally). The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression. Biochemistry and Biophysics Reports. 2021. in press

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Lectures and oral presentations (5)：

Mechanism of the uptake of naked single-stranded oligonucleotides into living cells
(The 34 th Annual Meeting of the Japanese Society for the Study of Xenobiotics in Tsukuba 2019)
Gymnosis関連分子とメカニズムの解明
(第22回バイオ治療法研究会学術集会 2018)
裸の1本鎖オリゴの細胞内への取り込みメカニズム
(第 17 回日本RNA学会年会 2015)
ヒトの血漿、末梢血単核細胞、培養細胞株由来のtRNase ZLをガイドする小さなRNA
(第56回新潟生化学懇話会 2015)
ヒト Bcl-2 mRNA を標的とする裸の RNA heptamer によるアポトーシス誘導
(第 11 回日本 RNA 学会年会)

Education (4)：

Professional career (3)：

Work history (12)：

2018/07 - 現在 Niigata University of Pharmacy and Applied Life Sciences
2018/07/01 - 現在 Niigata University of Pharmacy and Applied Life Sciences Research Institute for Healthy Living
2018/04 - 2018/06 Special researcher of the Japan Society for the Promotion of Science
2018/04 - 2018/06 Special researcher of the Japan Society for the Promotion of Science
2016/10 - 2018/03 Researcher

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Awards (6)：

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Association Membership(s) (1)：

RNA学会

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