Ogura Hideki

オグラヒデキ | Ogura Hideki

Homepage URL (1)： http://kaken.nii.ac.jp/d/r/20573174.ja.html

Research field (1)： Immunology

Research keywords (13)： T細胞 , microbiome , inflammatory bowel disease , type 1 diabetes , 関節炎 , 自己免疫疾患 , IL-17 , 4ステップモデル , 自己免疫 , IL-6 , IL-17A , 慢性炎症 , 線維芽細胞

Research theme for competitive and other funds (7)：

2022 - 2025 潰瘍性大腸炎における腸内細菌叢ー免疫系の相互作用の解析
2021 - 2024 潰瘍性大腸炎の病態解明に向けた回腸嚢炎の細菌叢解析
2019 - 2022 CD4+T細胞を軸とした新規炎症性腸疾患モデルにおける発症機構の解析
2018 - 2020 Exploration of diseases caused by MARCH dysregulation
2014 - 2015 慢性炎症に重要な炎症アンプの分子基盤の解析

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Papers (31)：

Keigo Nishida, Aiko Hasegawa, Satoru Yamasaki, Ryota Uchida, Wakana Ohashi, Yosuke Kurashima, Jun Kunisawa, Shunsuke Kimura, Toshihiko Iwanaga, Hiroshi Watarai, et al. Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis. Scientific reports. 2019. 9. 1. 10842-10842
Tanaka Y, Sabharwal L, Ota M, Nakagawa I, Jiang JJ, Arima Y, Ogura H, Okochi M, Ishii M, Kamimura D, et al. Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II. Journal of immunology (Baltimore, Md. : 1950). 2018. 201. 8. 2256-2263
Okuyama Y, Tanaka Y, Jiang JJ, Kamimura D, Nakamura A, Ota M, Ohki T, Higo D, Ogura H, Ishii N, et al. Bmi1 Regulates IκBα Degradation via Association with the SCF Complex. Journal of immunology (Baltimore, Md. : 1950). 2018. 201. 8. 2264-2272
Ogura H, Preston-Hurlburt P, Perdigoto AL, Amodio M, Krishnaswamy S, Clark P, Yu H, Egli D, Fouts A, Steck AK, et al. Identification and Analysis of Islet Antigen-Specific CD8⁺ T Cells with T Cell Libraries. Journal of immunology (Baltimore, Md. : 1950). 2018. 201. 6. 1662-1670
Toru Atsumi, Hironao Suzuki, Jing-Jing Jiang, Yuko Okuyama, Ikuma Nakagawa, Mitsutoshi Ota, Yuki Tanaka, Takuto Ohki, Kokichi Katsunuma, Koichi Nakajima, et al. Rbm10 regulates inflammation development via alternative splicing of Dnmt3b. International Immunology. 2017. 29. 12. 581-591

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MISC (7)：

Y. Okuyama, T. Atsumi, J. -J Jiang, A. Nakamura, H. Ogura, J. Meng, D. Kamimura, N. Shii, T. Hirano, M. Murakami. A novel regulator of NF kappa B signaling enhances I kappa B alpha ubiquitination and promotes inflammatory disease development. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 410-410
Masaaki Murakami, Masaya Harada, Daisuke Kamimura, Hideki Ogura, Yuko Okuyama, Noriko Kumai, Azusa Okuyama, Rajeev Singh, Jing-Jing Jiang, Toru Atsumi, et al. Disease-Association Analysis of an Inflammation-Related Feedback Loop (vol 3, pg 946, 2013). CELL REPORTS. 2013. 3. 5. 1754-1754
Inflammation amplifier (IL-6 amplifier) and its targets and regulators. 2013. 59. 3. 265-273
Daisuke Kamimura, Moe Yamada, Masaya Harada, Lavannya Sabharwal, Jie Meng, Hidenori Bando, Hideki Ogura, Toru Atsumi, Yasunobu Arima, Masaaki Murakami. The gateway theory: bridging neural and immune interactions in the CNS. FRONTIERS IN NEUROSCIENCE. 2013. 7
Masaaki Murakami, Yuko Okuyama, Hideki Ogura, Shogo Asano, Yasunobu Arima, Mineko Tsuruoka, Masaya Harada, Minoru Kanamoto, Yukihisa Sawa, Yoichiro Iwakura, et al. Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells (vol 208, pg 103, 2011). JOURNAL OF EXPERIMENTAL MEDICINE. 2012. 209. 12. 2321-2321

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