Rchr
J-GLOBAL ID：201401088582074685
Update date: Nov. 11, 2024
Makino Mai
マキノ マイ | Makino Mai
Affiliation and department：
Research field (3)：
Medical biochemistry
, Applied microbiology
, Biochemistry
Research keywords (3)：
ryanodine receptor
, protease
, enzyme
Research theme for competitive and other funds (3)：
- 2021 - 2024 2型リアノジン受容体の組織特異的スプライシングバリアントの心筋機能との関連の解明
- 2019 - 2021 2型リアノジン受容体の組織特異的スプライシングバリアントの存在意義の解明
- 2015 - 2016 ヒト由来保護タンパク質/カテプシンAの機能調節に関わる部位の検討
Papers (26)：
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Mai Makino, Shuhei Nakamura. A novel probe to monitor lysosome-mitochondria contact sites opens up a new path to study neurodegenerative diseases. Cell Calcium. 2024. 120. 102887
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Shin Takasawa, Mai Makino, Akiyo Yamauchi, Sumiyo Sakuramoto-Tsuchida, Rina Hirota, Ryusei Fujii, Keito Asai, Yoshinori Takeda, Tomoko Uchiyama, Ryogo Shobatake, et al. Intermittent hypoxia increased the expression of ESM1 and ICAM-1 in vascular endothelial cells via the downregulation of microRNA-181a1. Journal of Cellular and Molecular Medicine. 2024. 28. 1. e18039
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Shin Takasawa, Ryogo Shobatake, Asako Itaya-Hironaka, Mai Makino, Tomoko Uchiyama, Sumiyo Sakuramoto-Tsuchida, Yoshinori Takeda, Hiroyo Ota, Akiyo Yamauchi. Upregulation of IL-8, osteonectin, and myonectin mRNAs by intermittent hypoxia via OCT1- and NRF2-mediated mechanisms in skeletal muscle cells. Journal of Cellular and Molecular Medicine. 2022. 26. 24. 6019-6031
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Shin Takasawa, Asako Itaya-Hironaka, Mai Makino, Akiyo Yamauchi, Sumiyo Sakuramoto-Tsuchida, Tomoko Uchiyama, Ryogo Shobatake, Yoshinori Takeda, Hiroyo Ota. Upregulation of Reg IV and Hgf mRNAs by intermittent hypoxia via downregulation of microRNA-499 in cardiomyocytes. International Journal of Molecular Sciences. 2022. 23. 20. 12414
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Shin Takasawa, Chikatsugu Tsuchida, Sumiyo Sakuramoto-Tsuchida, Tomoko Uchiyama, Mai Makino, Akiyo Yamauchi, Asako Itaya-Hironaka. Upregulation of REG IV gene in human intestinal epithelial cells by lipopolysaccharide via downregulation of microRNA-24. Journal of Cellular and Molecular Medicine. 2022. 26. 17. 4710-4720
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MISC (1)：
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Yeast carboxypeptidase Y provides many interesting issues in protease studies. 2014. 61. 1. 50-55
Lectures and oral presentations (68)：
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Alteration of splice type in type 2 ryanodine receptor causes impaired insulin secretion in mice
(ADA 84th Scientific Sessions 2024)
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リソソームストレス応答に着目した神経・筋疾患発症進展メカニズムの解明
(第70 回日本生化学会近畿支部例会 2024)
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Attenuation of the CD38-cADPR signal system in cardiomyocytes by intermittent hypoxia via upregulation of Pten
(IDF2022 2022)
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間歇的低酸素は心筋細胞でPtenの発現を介して心筋機能に重要なCD38-cyclic ADP-ribose情報伝達系コンポーネントの発現低下を引き起こす
(第95回日本生化学会大会 2022)
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Up-regulation of dopamine β-hydroxylase and phenylethanolamine N-methyltransferase by intermittent hypoxia via down-regulation of microRNA-375 in neuronal cells
(58th EASD Annual Meeting 2022)
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Education (4)：
- 2019 - 現在 Nara Medical University
- 2011 - 2014 Nara Women's University Graduate School of Humanities and Sciences School of Natural Science and Ecological Awareness
- 2009 - 2011 Nara Women's University Graduate School of Humanities and Sciences Department of Food Science and Nutrition
- 2005 - 2009 Nara Women's University Faculty of Human Life and Environment Department of Food Science and Nutrition
Professional career (1)：
Work history (5)：
- 2016/04 - 現在 Nara Medical University
- 2014/09 - 2020/03 Osaka Electro-Communication University
- 2014/04 - 2016/03 Nara Women's University Assistant Professor
- 2014/04 - 2016/03 Nara Women's University Faculty, Division of Human Life and Environmental Sciences
- 2012 - 2014 Nara Medical University Medical Faculty, Medical Department
Committee career (2)：
- 2020/09 - 現在 日本生物高分子学会 理事
- 2014/09 - 現在 日本生物高分子学会 評議員
Awards (6)：
- 2022/02 - 国際ソロプチミスト奈良-あすか 大学院女子学生奨学金 クラブ賞
- 2020/03 - 奈良県立医科大学 Best TBL Teacher
- 2014 - 奈良女子大学大学院 人間文化研究科研究奨励賞
- 2013 - 日本生物高分子学会 日本生物高分子学会2013年度大会優秀発表賞
- 2012 - 奈良女子大学 廣部奨学金
- 2010 - 社団法人佐保会 佐保会奨学金
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Association Membership(s) (5)：
American Chemical Society
, The Protein Society
, 日本農芸化学会
, 日本生化学会
, 日本生物高分子学会
