TOMOYA AKAMA

アカマトモヤ | TOMOYA AKAMA

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/10548788.ja.html

Research field (2)： Cell biology , Biochemistry

Research theme for competitive and other funds (8)：

2024 - 2027 Elucidating mechanism of high-grade malignancy of lung adenocarcinoma focusing on carbohydrate antigen MECA-79
2021 - 2024 新規抗硫酸化糖鎖抗体の卵巣癌病理診断と光免疫療法への応用
2020 - 2023 Preferentially Expressed Antigen in Melanoma in thymic carcinoma: investigation of biological significance and application for novel therapy
2020 - 2023 Spatial pathology on invasive front and tertiary lymphoid structure in lung adenocarcinoma
2016 - 2018 Alteration of cornea thickness by modifying component of corneal extracellular matrix

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Papers (85)：

Akifumi Muramoto, Hitomi Hoshino, So Inamura, Masataka Murahashi, Tomoya O. Akama, Naoki Terada, Motohiro Kobayashi. Expression of Podocalyxin Potentially Decorated With Low-sulfated Keratan Sulfate in Human Testicular Embryonal Carcinoma. Journal of Histochemistry & Cytochemistry. 2024
Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura. GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium. Molecules (Basel, Switzerland). 2024. 29. 4
Hitomi Hoshino, Ya-Ying Chen, Daisuke Inoue, Yoshio Yoshida, Kay-Hooi Khoo, Tomoya O Akama, Motohiro Kobayashi. Expression of low-sulfated keratan sulfate in non-mucinous ovarian carcinoma. Glycobiology. 2023
Yuzuru Ariga, Shulin Low, Hitomi Hoshino, Tsutomu Nakada, Tomoya O Akama, Akifumi Muramoto, Mana Fukushima, Takahiro Yamauchi, Yusei Ohshima, Motohiro Kobayashi. Expression and Clinical Significance of Spi-B in B-cell Acute Lymphoblastic Leukemia. The journal of histochemistry and cytochemistry. 2022
Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O Akama, Kaho Nishioka, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura. Complementary Role of GlcNAc6ST2 and GlcNAc6ST3 in Synthesis of CL40-Reactive Sialylated and Sulfated Glycans in the Mouse Pleural Mesothelium. Molecules (Basel, Switzerland). 2022. 27. 14

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MISC (38)：

S. L. Littlechild, R. D. Young, B. Caterson, A. J. Quantock, T. O. Akama. The role of B-1,3-N-acetylglucosaminyltransferase-7 (B3GnT7) in the elongation of keratan sulfate glycosaminoglycans and corneal ultrastructure. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 2017. 98. 3. A14-A15
Toshiaki Shibata, Tomoya Akama, Kiyohiko Angata, Michiko Fukuda, Kazuhiro Sugihara, Naohiro Kanayama. Enhancement of Human Sperm Motility by Novel Recombinant Endo-beta-Galactosidases. REPRODUCTIVE SCIENCES. 2017. 24. 160A-161A
Hidetsugu Mori, Haruhiko Yamada, Kanji Takahashi, Tomoya Akama, Tomoyuki Nakamura. Changes in immunostaining of five elastic fiber components in Bruch's membrane and laser-induced choroidal neovascularization in mice. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016. 57. 12
Stacy L. Littlechild, Robert D. Young, Andrew J. Quantock, Tomoya O. Akama. Differential keratan sulfate proteoglycan phenotype in the beta-1,3-N-acetylglucosaminyltransferse-7 deficient mouse cornea. GLYCOBIOLOGY. 2015. 25. 11. 1257-1257
Tomoya O. Akama, Kiyohiko Angata, Tomoyuki Nakamura, Michiko N. Fukuda. Cloning of endo-beta-galactosidase from B. fragilis. GLYCOBIOLOGY. 2015. 25. 11. 1257-1258

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Lectures and oral presentations (32)：

新規硫酸化糖鎖抗体の作製
(第92回日本生化学会大会 2019)
Keratanase IIの最小酵素活性ドメインの同定
(第36回糖質学会年会 2017)
Development and age-related changes of the elastic lamina of Bruch’s membrane in mice eyes
(ARVO-ASIA 2017 2017)
B. fragilis endo-beta-galactosidaseのクローニングとその酵素活性解析
(第89回日本生化学会大会 2016)
細胞外マトリックスシートの力学物性計測
(日本結合組織学会 2016)

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Work history (1)：

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