Rchr
J-GLOBAL ID:201501005591850405   Update date: Dec. 05, 2024

Yoshihara Masahito

ヨシハラ マサヒト | Yoshihara Masahito
Affiliation and department:
Job title: Associate Professor
Other affiliations (3):
  • Chiba University  Department of Artificial Intelligence Medicine, Graduate School of Medicine   Associate Professor
  • Karolinska Institutet  Department of Medicine, Huddinge (MedH)   Visiting Researcher
  • Osaka University  Premium Research Institute for Human Metaverse Medicine (PRIMe)   Specially Appointed Professor
Homepage URL  (2): https://www.cn.chiba-u.jp/researcher/yoshihara_masahito/https://cn.chiba-u.jp/en/researcher/yoshihara_masahito/
Research field  (5): Systems genomics ,  Biological, health, and medical informatics ,  Genomics ,  Ophthalmology ,  Molecular biology
Research keywords  (5): induced pluripotent stem cells ,  Stem cells ,  regenerative medicine ,  Transcriptome ,  Bioinformatics
Research theme for competitive and other funds  (7):
  • 2023 - 2026 遺伝子治療実現に向けたヒト黄斑オルガノイドの開発
  • 2023 - 2025 高深度プロテオーム解析による増殖性硝子体網膜症の病態解明と治療標的探索
  • 2022 - 2025 フックス角膜内皮ジストロフィーの診療エビデンス創出のための研究
  • 2022 - 2024 ヒト神経分化モデルにおける網羅的エンハンサー制御アトラスから迫る病態解明
  • 2019 - 2021 Generation of human early embryo-like stem cells for regenerative medicine
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Papers (41):
  • Matthias Hörtenhuber, Marjo K Hytönen, Abdul Kadir Mukarram, Meharji Arumilli, César L Araujo, Ileana Quintero, Pernilla Syrjä, Niina Airas, Maria Kaukonen, Kaisa Kyöstilä, et al. The DoGA consortium expression atlas of promoters and genes in 100 canine tissues. Nature communications. 2024. 15. 1. 9082-9082
  • Yoshihiko Shitara, Ryo Konno, Masahito Yoshihara, Kohei Kashima, Atsushi Ito, Takeo Mukai, Goh Kimoto, Satsuki Kakiuchi, Masaki Ishikawa, Tomo Kakihara, et al. Host-derived protein profiles of human neonatal meconium across gestational ages. Nature communications. 2024. 15. 1. 5543-5543
  • Andrea Coschiera, Masahito Yoshihara, Gilbert Lauter, Sini Ezer, Mariangela Pucci, Haonan Li, Alan Kavšek, Christian G Riedel, Juha Kere, Peter Swoboda. Primary cilia promote the differentiation of human neurons through the WNT signaling pathway. BMC biology. 2024. 22. 1. 48-48
  • Sayo Maeno, Yoshinori Oie, Ryota Koto, Nozomi Nishida, Arisa Yamashita, Michika Yoshioka, Chifune Kai, Takeshi Soma, Shizuka Koh, Masahito Yoshihara, et al. Comparison of Scheimpflug and Anterior Segment Optical Coherence Tomography Imaging Parameters for Japanese Patients With Fuchs Endothelial Corneal Dystrophy With and Without TCF4 Repeat Expansions. Cornea. 2024. 43. 7. 805-811
  • Julia E. Niskanen, Åsa Ohlsson, Ingrid Ljungvall, Michaela Drögemüller, Robert F. Ernst, Dennis Dooijes, Hanneke W. M. van Deutekom, J. Peter van Tintelen, Christian J. B. Snijders Blok, Marion van Vugt, et al. Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human. Genome Medicine. 2023. 15. 1
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MISC (8):
  • 吉原 正仁, 設楽 佳彦, 渡辺 栄一郎, 川島 祐介, 紺野 亮. 新生児のうんち(初回胎便)のタンパク質組成を解明 -性別、在胎週数、疾患の有無で異なる-. 千葉大学:プレスリリース. 2024
  • Masahito Yoshihara. Towards A Better Understanding of Early Human Embryonic Development. CHIBA UNIVERSITY : Press release. 2023
  • 吉原 正仁. ES細胞よりもヒトの受精卵に近い段階の初期胚様細胞を効率よく作製~ヒトの初期発生のメカニズムのさらなる理解へ前進~. 千葉大学:プレスリリース. 2022
  • 吉原 正仁, 村川 泰裕, 林崎 良英, 安倍 真澄, 西田 幸二. iPS細胞におけるゲノム変異の解明 -iPS細胞樹立時に生じるゲノム変異のホットスポットを同定-. 理化学研究所:プレスリリース. 2017
  • YOSHIHARA MASAHITO. Commentary: Lens regeneration using endogenous stem cells for infant cataracts. 2016. 15. 3. 300
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Patents (2):
  • CORNEAL ENDOTHELIAL CELL MARKER AND UTILIZATION THEREOF
  • Corneal endothelial cell marker
Books (7):
  • ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
    技術情報協会 2023 ISBN:9784861049781
  • Current Topics in iPSCs Technology
    Academic Press / Elsevier 2022 ISBN:9780323998925
  • 再生医療の開発戦略と最新研究事例集
    技術情報協会 2019 ISBN:9784861047374
  • 遺伝統計学と疾患ゲノムデータ解析 - 病態解明から個別化医療,ゲノム創薬まで -
    メディカルドゥ 2018 ISBN:9784944157631
  • 実験医学別冊 最強のステップUPシリーズ シングルセル解析プロトコール わかる!使える! 1細胞特有の実験のコツから最新の応用まで.
    羊土社 2017 ISBN:9784758122344
more...
Lectures and oral presentations  (38):
  • Leveraging large-scale deep learning models for diagnosis and visual outcome prediction in retinitis pigmentosa patients
    (The 5th Annual Meeting of the Japanese Society of Artificial Intelligence in Ophthalmology 2024)
  • Generation of 8-cell-like cells (8CLCs) from human pluripotent stem cells
    (The 47th Annual Meeting of the Molecular Biology Society of Japan 2024)
  • 新生児X線画像の人工知能(AI)画像解析による疾患スクリーニングシステムの構築
    (第60回日本周産期・新生児医学会学術集会 2024)
  • Yolov5OBB (Oriented Bounding Box)を用いた新生児全身X線画像のセグメンテーションモデルの構築
    (第6回日本メディカルAI学会学術集会 2024)
  • 網羅的タンパク質解析技術を用いた胎便タンパク質解析研究
    (第7回臨床DOHaDセミナー 2024)
more...
Education (3):
  • 2013 - 2017 Osaka University Graduate School of Medicine
  • 2004 - 2010 Osaka University Faculty of Medicine
  • 2001 - 2004 Rakunan High School
Professional career (2):
  • M.D. (Osaka University)
  • Ph.D. (Osaka University)
Work history (13):
  • 2024/07 - 現在 Karolinska Institutet Department of Medicine, Huddinge (MedH) Visiting Researcher
  • 2023/12 - 現在 Osaka University Premium Research Institute for Human Metaverse Medicine (PRIMe) Specially Appointed Professor
  • 2022/04 - 現在 Chiba University Institute for Advanced Academic Research Associate Professor
  • 2022/04 - 現在 Chiba University Graduate School of Medicine Department of Artificial Intelligence Medicine Associate Professor
  • 2022/04 - 2024/07 Karolinska Institutet Department of Biosciences and Nutrition Visiting Researcher
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Awards (2):
  • 2015/09 - RIKEN SUMMER SCHOOL 2015 POSTER AWARD MEDICAL SCIENCE PRIZE
  • 2010/03 - Osaka University Kusumoto Award (The top graduate)
Association Membership(s) (6):
JAPANESE OPHTHALMOLOGICAL SOCIETY ,  JAPANESE SOCIETY FOR BIOINFORMATICS ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  日本角膜学会 ,  Japanese Association for Medical Artificial Intelligence ,  International Society for Stem Cell Research (ISSCR)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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