Research keywords (7)：
biomarker
, electrophoresis
, mass spectrometry
, 翻訳後修飾
, 疾患関連タンパク質
, プロテオーム
, プロテオミクス
Research theme for competitive and other funds (7)：
2023 - 2026 悪性膠芽腫の非コード領域由来ネオ抗原探索とその応用
2022 - 2025 着床期の胚・子宮内膜相互作用をコントロールする新規分子の解析
2019 - 2022 An integrative multi-omic analysis for biomarker discovery in glioblastoma
2016 - 2019 Development of novel diagnostic methods of carcinoma focused on epithelial-to-mesenchymal transition (EMT)
2016 - 2018 Molecular mechanism of MMP-7-enhanced liver metastasis of colon cancer, and its application for liver regenerative medicine
2011 - 2012 Development of monitoring method for the alteration of phosphorylation status in proteasome subunits using Phos-tag electrophoresis
2001 - 2001 酵母プロテアソームのN末端アセチル化と機能
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Papers (102)：
Yusuke Nakai, Ken Kumagai, Yoko Ino, Tomoko Akiyama, Kayano Moriyama, Yuriko Takeda, Kenji Egashira, Takashi Ohira, Akihide Ryo, Tomoyuki Saito, et al. Use of data-independent acquisition mass spectrometry to identify an objective serum indicator of the need for osteoporotic therapeutic intervention. Journal of proteomics. 2024. 300. 105166-105166
Kei Miyakawa, Masakazu Machida, Tomoyuki Kawasaki, Masatoshi Kakizaki, Yayoi Kimura, Masaya Sugiyama, Hideki Hasegawa, Akihiro Umezawa, Hidenori Akutsu, Akihide Ryo. Replication efficiency of SARS-CoV-2 Omicron subvariants BA.2.75, BA.5, and XBB.1 in human mini-gut organoids. Cellular and molecular gastroenterology and hepatology. 2024
Kyle J Preston, Tatsuo Kawai, Keiichi Torimoto, Ryohei Kuroda, Yuki Nakayama, Tomoko Akiyama, Yayoi Kimura, Rosario Scalia, Michael V Autieri, Victor Rizzo, et al. Mitochondrial fission inhibition protects against hypertension induced by angiotensin II. Hypertension research : official journal of the Japanese Society of Hypertension. 2024
Takashi Ohira, Yoko Ino, Naoyuki Kawao, Yuya Mizukami, Kiyotaka Okada, Osamu Matsuo, Hisashi Hirano, Yayoi Kimura, Hiroshi Kaji. Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice. Journal of applied physiology (Bethesda, Md. : 1985). 2024
中内美名, 井野洋子, 高橋仁, 信澤枝里, 宮川敬, 木村弥生, 梁明秀, 長谷川秀樹. Analysis of host factors interacting with nonstructural protein 1 of influenza A virus using proximity-dependent biotin identification. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
野口慶介, 鈴木秀文, 阿部竜太, 池陽子, 井野洋子, 木村弥生, 梁明秀, 土井宏, 田中章景, 山口雄輝, et al. Identification of the component of Cajal body by multi-omics analysis using antibody-based in situ biotinylation technique, and elucidation of mechanism of Cajal body formation. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
