Rchr
J-GLOBAL ID:201501011074691887
Update date: Sep. 21, 2024
Tojo Kentaro
トウジヨウ ケンタロウ | Tojo Kentaro
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
https://kaken.nii.ac.jp/d/r/80737552.ja.html
Research field (2):
Emergency medicine
, Anesthesiology
Research keywords (7):
Necroptosis
, Energy Metabolism
, Hypoxia Inducible Factor
, Cell Death
, Organ Dysfunction
, Sepsis
, ARDS
Research theme for competitive and other funds (17):
- 2024 - 2027 Cell-free RNAを用いた全身の細胞の状態を反映した多臓器障害サブフェノタイピング
- 2024 - 2027 大侵襲手術後PIICSの実態解明と予防的治療標的同定のための病態解析
- 2022 - 2025 好中球の包括的な免疫代謝解析に立脚した好中球機能の回復による敗血症治療法の開発
- 2020 - 2025 メラトニン/ラメルテオン投与による術後睡眠障害予防効果の検討
- 2021 - 2024 肺胞上皮細胞の自然免疫応答を標的とした院内肺炎予防法開発に向けた基盤研究
- 2021 - 2024 敗血症におけるインスリン抵抗性の生物学的意義の解析と治療応用に向けた基盤研究
- 2022 - 2023 肺胞上皮細胞のネクローシスを起点としたCOVID-19の重症化機構の解明と治療法開発
- 2019 - 2022 The trial to elucidate the mechanism underlying PICS after sepsis with stratified metabolome analysis.
- 2019 - 2022 肺動脈平滑筋細胞内シグナルに着目したARDSによる肺循環障害の新規治療標的の探索
- 2020 - 2021 敗血症に対する腸管上皮細胞特異的な低酸素誘導性因子活性化による腸管バリア保護の研究
- 2017 - 2020 Types of alveolar epithlial cell death during ARDS
- 2017 - 2020 Role of programmed necrosis in ARDS and the following remote organ injury
- 2016 - 2020 Analysis of energy metabolism of injured lung and its application
- 2019 - 2020 エネルギー代謝不全に注目した敗血症に伴う好中球機能障害の原因分子探索
- 2015 - 2018 Hypoxia-Inducible Factor as a Therapeutic Target for Acute Respiratory Distress Syndrome
- 2014 - 2018 Analysis of HIF-1 mediated energy metabolism during septic multiple organ dysfunction syndrome
- 2013 - 2016 Lung protective strategy by the gene delivery of lung epitherial grow factor.
Show all
Papers (22):
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Kentaro Tojo, Natsuhiro Yamamoto, Nao Tamada, Takahiro Mihara, Miyo Abe, Mototsugu Nishii, Ichiro Takeuchi, Takahisa Goto. Early alveolar epithelial cell necrosis is a potential driver of COVID-19-induced acute respiratory distress syndrome. iScience. 2022. 26. 1. 105748-105748
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Kentaro Tojo, Yamamoto Natsuhiro, Nao Tamada, Takahiro Mihara, Miyo Abe, Takahisa Goto. Early Alveolar Epithelial Cell Necrosis is a Potential Driver of ARDS with COVID-19. MedRxiv. 2022
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菊西 陽香, 井上 真光人, 山本 匠, 東條 健太郎, 吉田 輔, 横山 暢幸, 横瀬 真志, 入江 友哉, 高木 俊介, 後藤 隆久. 声門狭窄を合併した再発性多発軟骨炎患者の周術期気道管理の経験. 日本集中治療医学会雑誌. 2021. 28. Suppl.2. 362-362
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Kentaro Tojo, Yoh Sugawara, Yasufumi Oi, Fumihiro Ogawa, Takuma Higurashi, Yukihiro Yoshimura, Nobuyuki Miyata, Hajime Hayami, Yoshikazu Yamaguchi, Yoko Ishikawa, et al. Author Correction: The U-shaped association of serum iron level with disease severity in adult hospitalized patients with COVID-19. Scientific reports. 2021. 11. 1. 16949-16949
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Kentaro Tojo, Yoh Sugawara, Yasufumi Oi, Fumihiro Ogawa, Takuma Higurashi, Yukihiro Yoshimura, Nobuyuki Miyata, Hajime Hayami, Yoshikazu Yamaguchi, Yoko Ishikawa, et al. The U-shaped association of serum iron level with disease severity in adult hospitalized patients with COVID-19. Scientific Reports. 2021. 11. 1. 13431-13431
more...
MISC (3):
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K. Tojo, N. Yusuke, T. Yazawa, T. Mihara, T. Goto, K. Kurahashi. The distinct roles of hypoxia-activated transcription factors in atelectasis-induced lung injury: a pro-inflammatory role of nuclear factor-kappa B and an anti-inflammatory role of hypoxia-inducible factor-1 in lung epithelial cells. EUROPEAN JOURNAL OF ANAESTHESIOLOGY. 2014. 31. 1-1
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東條 健太郎, 長嶺 祐介, 矢澤 卓也, 後藤 隆久, 倉橋 清泰. 分離肺換気中の非換気側肺において無気肺に伴う低酸素が炎症を惹起する. 臨床呼吸生理. 2014. 46. 47-47
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K. Tojo, Y. Nagamine, S. Ota, Y. Baba, T. Goto, K. Kurahashi. Alveolar Hypoxia During One-Lung Ventilation Leads To Hif-1 Activation And Lung Inflammation In The Non-Ventilated Lung. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2013. 187
Education (2):
- 2010 - 2014 Yokohama City University Graduate School of Medicine
- 2000 - 2006 Chiba University School of Medicine
Professional career (1):
Work history (5):
- 2024/04 - 現在 Yokohama City University School of Medicine Department of Anesthesiology and Critical Care Medicine Associate Professor
- 2019/04 - 2024/03 Yokohama City University School of Medicine Department of Anesthesiology and Critical Care Medicine Assistant Professor
- 2017/04 - 2019/03 Yokohama City University School of Medicine Department of Anesthesiology and Critical Care Medicine Assistant Professor
- 2016/04 - 2017/03 Yokohama City University School of Medicine Department of Anesthesiology and Critical Care Medicine Assistant Professor
- 2010/04 - 2016/03 Yokohama City University Hospital Department of Anesthesiology and Critical Care Medicine
Awards (2):
- 2017/06 - Japanese Society of Anesthesiologists Best Presentation Award, The 64th Annual Meeting of the Japanese Society of Anesthesiologists
- 2014/06 - European Society of Anaesthesiology 2014 Euroanaesthesia Best Abstract Prize 3rd Prize
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