Nakayama Hirotaka

ナカヤマヒロタカ | Nakayama Hirotaka

Affiliation and department：
Homepage URL (1)： http://www.first-surgery.jp/

Research field (1)： General surgery, pediatric surgery

Research keywords (6)： EZH2 , epigenetics , breast cancer , Ki-67 , BRAF , thyroid cancer

Research theme for competitive and other funds (2)：

2019 - 2023 Establishment of novel drug susceptibility testing and biomarker using anaplastic thyroid cancer organoid
2019 - 2023 甲状腺未分化癌におけるエピジェネティクスをターゲットとした治療戦略

Papers (59)：

Hirotaka Nakayama, Nao Saito, Rika Kasajima, Nobuyasu Suganuma, Yasushi Rino, Katsuhiko Masudo, Haruhiko Yamazaki, Soji Toda, Kazumasa Sekihara, Hiroyuki Iwasaki, et al. Validation of EZH2 Inhibitor Efficiency in Anaplastic Thyroid Carcinoma Cell Lines. Anticancer research. 2023. 43. 3. 1073-1077
Haruhiko Yamazaki, Hiroyuki Iwasaki, Nobuyasu Suganuma, Soji Toda, Katsuhiko Masudo, Hirotaka Nakayama, Yasushi Rino, Munetaka Masuda. Inflammatory biomarkers and dynamics of neutrophil-to-lymphocyte ratio in lenvatinib treatment for anaplastic thyroid carcinoma. Gland Surgery. 2021. 10. 3. 852-860
Tatsuya Yoshida, Nobuyasu Suganuma, Shinya Sato, Soji Toda, Hirotaka Nakayama, Katsuhiko Masudo, Yoichiro Okubo, Hiroyuki Hayashi, Tomoyuki Yokose, Naohiko Koshikawa, et al. Membrane type 1 matrix metalloproteinase regulates anaplastic thyroid carcinoma cell growth and invasion into the collagen matrix. Biochemical and Biophysical Research Communications. 2020. 529. 4. 1195-1200
Haruhiko Yamazaki, Tomoyuki Yokose, Hiroyuki Hayashi, Hiroyuki Iwasaki, Sachie Osanai, Nobuyasu Suganuma, Hirotaka Nakayama, Katsuhiko Masudo, Yasushi Rino, Munetaka Masuda. Expression of fibroblast growth factor receptor 4 and clinical response to lenvatinib in patients with anaplastic thyroid carcinoma: a pilot study. European Journal of Clinical Pharmacology. 2020. 76. 5. 703-709
Hirotaka Nakayama, Kae Kawachi, Nobuyasu Suganuma, Tatsuya Yoshida, Toshinari Yamashita, Takashi Yamanaka, Yuka Matsubara, Kaori Kohagura, Soji Toda, Yoshiyasu Nakamura, et al. EZH2 and MMSET Were Identified as Potentially Useful Therapeutic Targets in Metaplastic Breast Carcinoma. Anticancer research. 2020. 40. 4. 2133-2139

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MISC (10)：

A CASE OF LARGE SUBSTERNAL GOITER THAT WAS SUCCESSFULLY RESECTED VIA A CERVICAL APPROACH. 2016. 67. 4. 567-570
Hitoshi Inari, Nobuyasu Suganuma, Kae Kawachi, Tatsuya Yoshida, Hirotaka Nakayama, Takashi Yamanaka, Ayumi Yamanaka, Takashi Oshima, Yasushi Rino, Satoru Shimizu, et al. Correlation of expression of enhancer of zeste homolog 2 with the survival outcome in patients with metastatic breast cancer using primary and paired metastatic lesions. JOURNAL OF CLINICAL ONCOLOGY. 2016. 34. 15
Hitoshi Inari, Satoru Shimizu, Tatsuya Yoshida, Nobuyasu Suganuma, Takashi Yamanaka, Hirotaka Nakayama, Ayumi Yamanaka, Yasushi Rino, Munetaka Masuda. A comparison of clinicopathological characteristics and survival outcomes between symptomatic and screen detected breast cancer in Japanese women. JOURNAL OF CLINICAL ONCOLOGY. 2015. 33. 28
A CASE OF MATRIX-PRODUCING CARCINOMA OF THE BREAST. 2015. 66. 1. 45-48
嘉数彩乃, 吉田明, 小島いずみ, 山中隆司, 中山博貴, 吉田達也, 稲葉將陽, 清水哲, 鷲見公太, 益田宗孝. 術後11年後に他癌死した甲状腺未分化癌の1例. 日本内分泌・甲状腺外科学会雑誌. 2015. 32. Suppl.1. S135-S135

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Professional career (1)：

医学博士 (横浜市立大学)

Work history (1)：

Yokohama City University Hospital General Surgery Assistant Professor

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