Hirofumi Noguchi

2021 - 2024 Induction of tissue-specific stem cells by novel transcription factors and/or small-molecule compounds

2021 - 2024 歯の再生を目指したヒト乳歯歯髄幹細胞濃縮と機能解析

2019 - 2024 細胞骨格ダイナミクスに基づく分子輸送制御システムの解明と革新的癌創薬への新展開

2020 - 2023 Differentiatio of human stem cells into pancreatic islets using porcine body as in vivo bioreactor

2020 - 2023 Molecular biological approaches to gene therapy for hypophosphatosis

2020 - 2023 Functional analysis of alkaline phosphatase, a stem cell marker, using human deciduous dental pulp cells derived from the patient with Hypophosphatasia (HPP)

2019 - 2022 Development of the differentiation derivative methods from induced tissue-specific pancreatic stem cells using TASCL to insulin excretory cells

2018 - 2021 Development of culture method to promote differentiation induction of pancreatic beta cells

2018 - 2021 Isolation and characterization of somatic stem cells from human deciduous tooth-derived dental pulp cells by genetic engineering techniques

2017 - 2020 A study on molecular robotics blood glucose level control method with NOD mice

2017 - 2020 Regeneration of insulin producing cells from Human deciduous dental pulp cell derived iPS cells

2017 - 2019 初期胚特異抗原SSEA-1が高未分化iPS細胞を特定するマーカーであることの証明

2016 - 2019 Induction of human iTS-P and iTS-L cells using iPS cell technology

2016 - 2019 Induction of Expandable Adipose-Derived Mesenchymal Stem Cells from Aged Mesenchymal Stem Cells by a Synthetic Self-Replicationg RNA.

2016 - 2019 Development and usage of p38MAPK inhibitory peptides

2016 - 2019 Development of gene transfer to peripheral tissues surrounding tooth (GTPT) for the tissue around the root forming apex of juvenile mice and its application

2016 - 2019 The visualization of microtissues using near-infrared fluorescence endoscope

2016 - 2019 Regeneration strategy of the functional renal corpuscle using renal stem cells

2015 - 2019 Elucidation of the unitary regulation on the malignant transformation and androgen insensitivity in prostate cancer.

2015 - 2018 Development of cryopreservation system for cells and tissue constructs in regenerative medicine and transplantation

2014 - 2018 Continuous hypothermic machine perfusion preservation of pancreas for efficient islet transplantation

2015 - 2017 次世代型標的遺伝子破壊法CRISPR/Cas9システムの歯学領域への応用

2014 - 2017 The isolation of stem cells from the human exfoliated deciduous teeth by genetic engineering

2014 - 2017 Development of xeno-free human feeder cell with multi-function derived from the dental pulp cell

2013 - 2017 The tooth-format cellular differentiating regulation from iPSCs

2013 - 2017 Establishment and applicational research of androgen producing stem cells

2013 - 2017 Preferential enrichment and characterization of human dental pulp stem cell via a genetic engineering-based approach

2014 - 2016 A novel NFAT inhibitory peptide (RCAN-11R) provides immunosuppression.

2013 - 2016 The study of regeneration of fetal small intestinal mucosa on the denuded colon

2013 - 2016 Construction of a cytotoxicity and function evaluation system using combinatorial cell clusters with magnetic nanoparticles

2013 - 2016 Induction and isolation of renal stem cells and establishment of foundation for renal regeneration research.

2012 - 2015 Establishment of 4th generation of islet isolation and the clinical application

2012 - 2015 Oct-3/4, a member of the family of POU-domain transcriptional factors can be the promising markers for cancer stem cells.

2011 - 2015 Effectiveness for islet isolation by hypothermic machine perfusion presevation of pancreas

2011 - 2013 蛋白導入法を用いた新規免疫抑制剤の開発

2011 - 2013 Production and application of a dental hypoplasia mouse model using a specific organization and a cell disruption system

2011 - 2013 Enrichment of the tooth constitution cell derived from human iPS cells using an original technique

2005 - 2006 膵島移植成績向上のための新規免疫抑制剤開発、および膵島再生療法の臨床応用化

2005 - 2005 新規細胞導入ペプチドによる膵島移植後の生着率向上効果の検討

2005 - 2005 ヒト膵島分離後の膵非内分泌組織からの膵幹細胞の同定と膵β細胞への分化誘導法の確立