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J-GLOBAL ID：201501013507209735   Update date: Apr. 23, 2024

Sachiko Inubushi

イヌブシ サチコ | Sachiko Inubushi
Affiliation and department：
Kobe University Graduate School of Medicine Faculty of Medical Sciences

About Kobe University Graduate School of Medicine Faculty of Medical Sciences


Research field  (1)： Tumor biology
Research keywords  (4)： virus ,  miRNA ,  extracellular vesicle ,  exosome
Research theme for competitive and other funds  (13)：
  • 2024 - 2027 乳癌の早期診断のための涙液バイオマーカーの探索
  • 2021 - 2024 涙液を用いた新しい乳癌早期診断法の確立
  • 2021 - 2024 Development and application of an early detection method for postoperative recurrence of colorectal cancer using tears
  • 2021 - 2024 Subset cell analysis of gynecological cancer-associated fibroblast that induce lymph node metastasis.
  • 2021 - 2024 がん早期診断における涙液エクソソームの有用性の検討
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Papers (41)：
  • Sachiko Mizumoto, Sachiko Inubushi, Mayuko Miki, Haruna Nakamura, Motoi Baba, Yuji Yamashita, Mayuko Yamamoto, Shotaro Inoue, Hirokazu Tanino, Tomonari Kunihisa. Target-Oriented Classification of Triple-negative Breast Cancer. Anticancer research. 2023. 43. 11. 5067-5072
  • Chihiro Wakayama, Sachiko Inubushi, Tomonari Kunihisa, Sachiko Mizumoto, Motoi Baba, Hirokazu Tanino, Ik Sung Cho, Tooru Ooya. Protein corona formation on epigallocatechin gallate-Au nanoparticles suppressed tumor accumulation. JCIS Open. 2023. 9
  • Sachiko Inubushi, Tomonari Kunihisa, Sachiko Mizumoto, Shotaro Inoue, Mayuko Miki, Atsushi Suetsugu, Hirokazu Tanino, Robert M Hoffman. Methionine Restriction Increases Exosome Production and Secretion in Breast Cancer Cells. Cancer genomics & proteomics. 2023. 20. 5. 412-416
  • Yusuke Aoki, Qinghong Han, Yasunori Tome, Jun Yamamoto, Yutaro Kubota, Noriyuki Masaki, Koya Obara, Kazuyuki Hamada, Justin D. Wang, Sachiko Inubushi, et al. Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation. Frontiers in Oncology. 2022. 12. 1009548-1009548
  • Jun Yamamoto, Sachiko Inubushi, Qinghong Han, Yoshihiko Tashiro, Norihiko Sugisawa, Kazuyuki Hamada, Yusuke Aoki, Kentaro Miyake, Ryusei Matsuyama, Michael Bouvet, et al. Linkage of methionine addiction, histone lysine hypermethylation, and malignancy. iScience. 2022. 25. 4. 104162-104162
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MISC (7)：
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Patents (1)：
Books (2)：
  • The current status of space modulated radiotherapy
    2016
  • Medical Application of Nonwoven Fabrics - Intra-abdominal Spacers for Particle Therapy
    2016
Lectures and oral presentations  (16)：
  • インタクトエクソソームによる乳がん高速検知のための抗体融合分子インプリントセンシングチップ
    (応用物理学会秋季学術講演会講演予稿集(CD-ROM) 2019)
  • 小児がんに対する吸収性スペーサー留置を併用した粒子線治療
    (日本小児血液・がん学会雑誌(Web) 2019)
  • 放射線照射によって分泌された子宮頸部腺がん細胞由来エクソソームのBystander効果の検討
    (日本細胞外小胞学会 2018 2018)
  • 過酸化チタンナノ粒子の併用による放射線増感治療法の開発
    (日本DDS学会学術集会プログラム予稿集 2018)
  • Bystander effect of exosomes derived from cervical adenocarcinoma cells in response to irradiation
    (ISEV 2019 2018)
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Education (3)：
  • - 2010 神戸大学 大学院医学系研究科博士課程医科学専攻修了
  • 1997 - 2001 Fukui Prefectural University Faculty of Biotechnology Department of Bioscience
  • - 1997 親和女子高等学校
Work history (6)：
  • 2020/04 - 現在 Kobe University Graduate School of Medicine
  • 2019/08 - 2020/01 University of California, San Diego (UCSD) visiting researcher
  • 2015/07 - 2019/06 Kobe University Graduate School of Medicine
  • 2014/07 - 2015/06 Kobe University
  • 2010/04 - 2012/03 The University of Tokushima The Institute for Enzyme Research
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