Research theme for competitive and other funds (4)：
2019 - 2024 ポリコム群による抑制ドメインの複製機構の解明
2012 - 2014 Commensal microbiota maintains gut homeostasis through epigenetic modification
2007 - 2011 Genome-wide identification of genes for anorexia and their cascade analysis on disease development by functional study
2008 - 2010 Dissecting molecular mechanisms mediated by Polycomb group proteins in maintenance and differentiation of ES cells
Papers (14)：
Yasuhide Ohinata, Takaho A Endo, Hiroki Sugishita, Takashi Watanabe, Yusuke Iizuka, Yurie Kawamoto, Atsunori Saraya, Mami Kumon, Yoko Koseki, Takashi Kondo, et al. Establishment of mouse stem cells that can recapitulate the developmental potential of primitive endoderm. Science (New York, N.Y.). 2022. 375. 6580. 574-578
Mitsuhiro Endoh, Takaho A Endo, Jun Shinga, Katsuhiko Hayashi, Anca Farcas, Kit-Wan Ma, Shinsuke Ito, Jafar Sharif, Tamie Endoh, Naoko Onaga, et al. PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. eLife. 2017. 6
Xiangzhi Li, Kyo-ichi Isono, Daisuke Yamada, Takaho A. Endo, Mitsuhiro Endoh, Jun Shinga, Yoko Mizutani-Koseki, Arie P. Otte, Miguel Casanova, Hiroshi Kitamura, et al. Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes (vol 31, pg 351, 2011). MOLECULAR AND CELLULAR BIOLOGY. 2014. 34. 14. 2773-2773
Takashi Kondo, Kyoichi Isono, Kaori Kondo, Takaho A. Endo, Shigeyoshi Itohara, Miguel Vidal, Haruhiko Koseki. Polycomb Potentiates Meis2 Activation in Midbrain by Mediating Interaction of the Promoter with a Tissue-Specific Enhancer. DEVELOPMENTAL CELL. 2014. 28. 1. 94-101
