Rchr
J-GLOBAL ID:201501020103927029
Update date: Sep. 28, 2024
Shinohara Ryota
シノハラ リョウタ | Shinohara Ryota
Affiliation and department:
Job title:
Associate Professor
Research field (3):
Pharmacology
, Neuroscience - general
, Psychiatry
Research theme for competitive and other funds (8):
- 2022 - 2025 Elucidation of neural circuit mechanisms underlying diversity in behavioral changes induced by chronic stress
- 2021 - 2025 Elucidation of the molecular and neural circuit basis of individual differences in stress resilience
- 2021 - 2022 Elucidation of the neural basis underlying individual differences in brain dysfunction caused by chronic stress
- 2017 - 2019 Molecular and neural circuit mechanisms underlying rapid antidepressant actions
- 2017 - 2018 Identifying the molecular and neural circuit mechanisms of the action of rapid-acting antidepressants
- 2016 - 2018 ドパミン受容体を介した前頭前皮質の神経回路成熟と情動制御での役割
- 2013 - 2016 慢性ストレスによる前頭前皮質の機能変化の分子基盤とその役割
- 2010 - 2012 神経発生におけるRho標的分子mDiaの役割
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Papers (17):
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Ryota Shinohara, Tomoyuki Furuyashiki. Prefrontal contributions to mental resilience: Lessons from rodent studies of stress and antidepressant actions. Neuroscience Research. 2022
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Satoshi Akiyama, Hirotaka Nagai, Shota Oike, Io Horikawa, Masakazu Shinohara, Yabin Lu, Takashi Futamura, Ryota Shinohara, Shiho Kitaoka, Tomoyuki Furuyashiki. Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice. Scientific Reports. 2022. 12. 1. 11385-11385
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Ryota Shinohara, George K. Aghajanian, Chadi G. Abdallah. Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities. Biological Psychiatry. 2020
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Santosh Pothula, Taro Kato, Rong-Jian Liu, Min Wu, Danielle Gerhard, Ryota Shinohara, Alexa-Nicole Sliby, Golam M. I. Chowdhury, Kevin L. Behar, Gerard Sanacora, et al. Cell-type specific modulation of NMDA receptors triggers antidepressant actions. Molecular Psychiatry. 2020
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Ronald S. Duman, Ryota Shinohara, Manoela V. Fogaça, Brendan Hare. Neurobiology of rapid-acting antidepressants: convergent effects on GluA1-synaptic function. Molecular Psychiatry. 2019. 24. 12. 1816-1832
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MISC (30):
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Ryota Shinohara. レジリエンスにおける前頭前皮質ドパミン系の役割. Medical Science Digest. 2023. 49. 3
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Yuki Okuda, Ryota Shinohara, Hirokazu Sonobe, Yuzuki Maruyama, Masahiro Yamaguchi, Kei Ito, Akinori Sato, Fumitaka Osakada, Tomoyuki Furuyashiki. Chronic social stress causes long-term structural alterations of neuronal projections to the medial prefrontal cortex in mice. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 2-B
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Toshihiro Hisasue, Qing Zhu, Yuka Ishikawa, Taro Kato, Shinichi Ishii, Yoshio Katayama, Yuta Yamaguchi, Ryota Shinohara, Tomoyuki Furuyashiki. Neutrophil mobilization is crucial for chronic social stress-induced behavioral alterations in mice. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 3-B
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Ryota Shinohara. Neural circuit mechanisms of rapid antidepressant actions of ketamine. Folia Pharmacologica Japonica. 2022. 157. 5. 386-386
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Ryota Shinohara, Brendan D. Hare, Rong-Jian Liu, Jin Hua Li, Xiao-Yuan Li, Catharine H. Duman, Ralph J. DiLeone, Ronald S. Duman. Distinct downstream targets of the medial prefrontal cortex underlie discrete antidepressant responses to ketamine. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-O
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Patents (1):
Lectures and oral presentations (26):
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慢性ストレスによる神経回路再編と行動変容での役割
(2024年度生理学研究所研究会「情動研究会2024」 2024)
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Alterations in prefrontal cortex circuits caused by chronic social stress
(The 46th Annual Meeting of the Japan Neuroscience Society 2023)
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Roles of prefrontal dopamine D1 receptors in stress resilience and antidepressant actions of ketamine
(「次世代脳」プロジェクト 冬のシンポジウム2022 新学術領域「マルチスケール脳」企画シンポジウム 2022)
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Analysis of neural circuit alterations caused by chronic social stress
(The 96th Annual Meeting of the Japanese Pharmacological Society 2022)
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Study on mechanisms and pathophysiological significance of neural circuit formation and plasticity
(BPCNPNPPP2022 (Japanese Society of Neuropsychopharmacology Young Investigator Award Lecture) 2022)
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Education (1):
- 2008 - 2012 Kyoto University Graduate School of Medicine
Professional career (1):
Work history (10):
- 2024/04 - 現在 Kobe University Graduate School of Medicine Associate Professor
- 2021/07 - 2024/03 Kobe University Graduate School of Medicine Associate Professor
- 2021/04 - 2021/06 Kobe University Graduate School of Medicine Associate Professor
- 2019/09 - 2021/03 Yale University School of Medicine Department of Psychiatry Associate Research Scientist
- 2017/09 - 2019/08 Yale University School of Medicine Department of Psychiatry Postdoctoral Fellow
- 2016/10 - 2017/09 Kobe University Graduate School of Medicine Assistant Professor
- 2015/09 - 2016/09 Kobe University Graduate School of Medicine Research Assistant Professor
- 2013/04 - 2015/08 Japan Society for the Promotion of Science Research Fellowship for Young Scientists (PD)
- 2012/04 - 2013/03 Kyoto University Graduate School of Medicine Postdoctoral Fellow
- 2010/04 - 2012/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists (DC2)
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Awards (4):
- 2022/11 - The Japanese Society of Neuropsychopharmacology Young Investigator Award Study on mechanisms and pathophysiological significance of neural circuit formation and plasticity
- 2022/06 - 国立大学法人神戸大学 令和4年度優秀若手研究者賞
- 2022/03 - The Japanese Pharmacological Society Young Investigator Award Elucidation of mechanisms and pathophysiological significance of neural circuit formation and plasticity
- 2013/02 - Inoue Foundation for Science 29th Inoue Research Award for Young Scientists
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