Rchr
J-GLOBAL ID:201501020103927029   Update date: Nov. 16, 2022

Shinohara Ryota

シノハラ リョウタ | Shinohara Ryota
Affiliation and department:
Job title: Associate Professor
Research field  (3): Pharmacology ,  Neuroscience - general ,  Psychiatry
Research theme for competitive and other funds  (4):
  • 2021 - 2025 Elucidation of the molecular and neural circuit basis of individual differences in stress resilience
  • 2016 - 2018 ドパミン受容体を介した前頭前皮質の神経回路成熟と情動制御での役割
  • 2013 - 2016 慢性ストレスによる前頭前皮質の機能変化の分子基盤とその役割
  • 2010 - 2012 神経発生におけるRho標的分子mDiaの役割
Papers (16):
  • Satoshi Akiyama, Hirotaka Nagai, Shota Oike, Io Horikawa, Masakazu Shinohara, Yabin Lu, Takashi Futamura, Ryota Shinohara, Shiho Kitaoka, Tomoyuki Furuyashiki. Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice. Scientific Reports. 2022. 12. 1. 11385-11385
  • Ryota Shinohara, George K. Aghajanian, Chadi G. Abdallah. Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities. Biological Psychiatry. 2020
  • Santosh Pothula, Taro Kato, Rong-Jian Liu, Min Wu, Danielle Gerhard, Ryota Shinohara, Alexa-Nicole Sliby, Golam M. I. Chowdhury, Kevin L. Behar, Gerard Sanacora, et al. Cell-type specific modulation of NMDA receptors triggers antidepressant actions. Molecular Psychiatry. 2020
  • Ronald S. Duman, Ryota Shinohara, Manoela V. Fogaça, Brendan Hare. Neurobiology of rapid-acting antidepressants: convergent effects on GluA1-synaptic function. Molecular Psychiatry. 2019. 24. 12. 1816-1832
  • Chisato Numa, Hirotaka Nagai, Masayuki Taniguchi, Midori Nagai, Ryota Shinohara, Tomoyuki Furuyashiki. Social defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex. Scientific Reports. 2019. 9. 1
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MISC (5):
Lectures and oral presentations  (15):
  • A neural circuit mechanism underlying rapid antidepressant actions of ketamine
    (The 44th Annual Meeting of the Japan Neuroscience Society / The 1st CJK International Meeting 2021)
  • Distinct projection targets of dopamine D1 receptor-expressing neurons in the prefrontal cortex underlying antidepressant responses to ketamine
    (The 43rd Annual Meeting of the Japanese Society of Biological Psychiatry (JSBP) / The 51st Annual Meeting of the Japanese Society of Neuropsychopharmacology (JSNP) 2021)
  • Distinct projections of the medial prefrontal cortex underlie the rapid antidepressant actions of ketamine
    (Neuroscience 2019 2019)
  • Dissecting neural circuits underlying stress and rapid antidepressant actions in animal models
    (Biological Sciences Training Program (BSTP) Seminar Series 2019)
  • Identifying the molecular and neural circuit mechanisms of the action of rapid-acting antidepressants
    (The 42nd Annual Meeting of the Japan Neuroscience Society 2019)
more...
Education (1):
  • 2008 - 2012 Kyoto University Graduate School of Medicine
Professional career (1):
  • Ph.D. (Kyoto University)
Work history (9):
  • 2021/07 - 現在 Kobe University Graduate School of Medicine Associate Professor
  • 2021/04 - 2021/06 Kobe University Graduate School of Medicine Associate Professor
  • 2019/09 - 2021/03 Yale University School of Medicine Department of Psychiatry Associate Research Scientist
  • 2017/09 - 2019/08 Yale University School of Medicine Department of Psychiatry Postdoctoral Fellow
  • 2016/10 - 2017/09 Kobe University Graduate School of Medicine Assistant Professor
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Awards (7):
  • 2022/11 - The Japanese Society of Neuropsychopharmacology Young Investigator Award Study on mechanisms and pathophysiological significance of neural circuit formation and plasticity
  • 2022/06 - 国立大学法人神戸大学 令和4年度優秀若手研究者賞
  • 2022/03 - The Japanese Pharmacological Society Young Investigator Award Elucidation of mechanisms and pathophysiological significance of neural circuit formation and plasticity
  • 2017/09 - National Institute for Physiological Sciences Japan-U.S. Brain Research Cooperation Program
  • 2017/09 - The Uehara Memorial Foundation Research Fellowship
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