Rchr
J-GLOBAL ID:201501026441527572
Update date: May. 11, 2024
Takaoka Yousuke
タカオカ ヨウスケ | Takaoka Yousuke
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://www.orgchem1.chem.tohoku.ac.jp/orgchem1/Home.html
Research field (1):
Plants: molecular biology and physiology
Research keywords (1):
Chemical Biology
Research theme for competitive and other funds (16):
- 2022 - 2025 Analyses of the relationship between degradation and function of plant hormone receptors by using chemical tools
- 2021 - 2023 Development of selective chemical tool box useful for analyses of the ubiquitin ligase substrates
- 2020 - 2023 Chemical biology of natural products on plant hormones
- 2019 - 2022 Regulation of plant hormone receptor using stereochemical isomers of a natural product
- 2018 - 2022 Regulation of protein-protein interaction of phytohormone co-receptor with molecular-targeted reactive drug
- 2017 - 2022 Studies on chemical communication on host-selective toxins
- 2019 - 2021 Development of random loop-stapling peptide for ubiquitin code analyses
- 2017 - 2020 Chemical biology of natural products involved in plant-microbe interaction
- 2016 - 2020 Comprehensive analysis of environmental responsive biomarkers by ambiguous control of plant hormone activity
- 2016 - 2018 Development of novel methods for efficient derivery system of functional molecular probes in plant cells
- 2013 - 2017 Real time and reversible imaging of cytokine receptors on living cells based on supramolecular approaches
- 2014 - 2016 改良型リガンド指向性触媒反応による細胞内標的タンパク質の効率的ラベル化技術の構築
- 2012 - 2014 多点反応性ラベル化剤による天然物リガンド標的タンパク質化学修飾法の開発
- 2011 - 2012 Development of Chemical Protein Labeling method for Spatiotemporal Modulation of Endogenous Protein Activity in Cells
- 2010 - 2010 タンパク質間相互作用に基づくバイオセンサー構築と神経栄養因子のリアルタイム検出
- 2007 - 2009 細胞内でのタンデム有機反応によるタンパク質のバイオセンサーへの機能化
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Papers (51):
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Rina Saito, Yuho Nishizato, Tsumugi Kitajima, Misuzu Nakayama, Yousuke Takaoka, Nobuki Kato, Minoru Ueda. Downstream metabolites of (+)-cis-12-oxo-phytodienoic acid function as noncanonical bioactive jasmonates inArabidopsis thaliana. 2024
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Takuya Kaji, Kotaro Matsumoto, Taichi Okumura, Misuzu Nakayama, Shunji Hoshino, Yousuke Takaoka, Jianxin Wang, Minoru Ueda. Two distinct modes of action of molecular glues in the plant hormone co-receptor COI1-JAZ system. iScience. 2023. 108625-108625
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Takaoka Yousuke. Subtype-selective agonists of plant hormone co-receptor COI1-JAZs identified from the stereoisomers of coronatine. Communications Biology. 2023
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Hideo Inagaki, Kengo Hayashi, Yousuke Takaoka, Hibiki Ito, Yuki Fukumoto, Ayaka Yajima-Nakagawa, Xi Chen, Miyuki Shimosato-Nonaka, Emmi Hassett, Kodai Hatakeyama, et al. Genome Editing Reveals both the Crucial Role of OsCOI2 in Jasmonate Signaling, and the Functional Diversity of COI1 Homologs in Rice Functional Diversity of COI1 Homologs in Rice. Plant & cell physiology. 2022. 64. 4. 405-421
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Ruiqi Liu, Hikaru Niimi, Minoru Ueda, Yousuke Takaoka. Coordinately regulated transcription factors EIN3/EIL1 and MYCs in ethylene and jasmonate signaling interact with the same domain of MED25. Bioscience, biotechnology, and biochemistry. 2022
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MISC (21):
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稲垣秀生, 湯本絵美, 高岡洋輔, 岡田憲典, 上田実, 上田実, 宮本皓司. イネのジャスモン酸受容体OsCOI2の下流シグナル伝達の解明. 日本植物学会大会研究発表記録(CD-ROM). 2023. 87th
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林謙吾, 加藤信樹, 野本春菜, 中山美涼, 加治拓哉, 渡部楽, 齊藤里菜, 高岡洋輔, 宮本皓司, 稲垣秀生, et al. Development of receptor subtype selective ligands via focused library screening composed of stereoisomers of coronatine. 日本化学会春季年会講演予稿集(Web). 2021. 101st
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林謙吾, 加藤信樹, 渡部楽, 高岡洋輔, 野本春菜, 中山美涼, 宮川咲季, 宮本皓司, 稲垣秀生, 岡田憲典, et al. Development of receptor subtype selective ligands via focused library screening composed of stereoisomers of coronatine. 天然有機化合物討論会講演要旨集(Web). 2020. 62nd
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高岡洋輔, 高岡洋輔, 上田実, 上田実. 植物ホルモン・ジャスモン酸の多様な活性を制御するケミカルツールの合理的設計 植物の生長と防御を操作する化合物の創製. 化学と生物. 2020. 58. 4
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高岡洋輔, 高岡洋輔. 植物細胞への機能性小分子の送達と局在制御. アグリバイオ. 2019. 3. 2
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Lectures and oral presentations (1):
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Self-assembling turn-on nanoprobe for endogenous protein sensing
(China/Japan Young Chemists Forum 2014)
Education (1):
- 2007 - 2010 Kyoto University Graduate School of Engineering Department of Synthetic Chemistry and Biological Chemistry
Professional career (1):
Work history (5):
- 2020/04 - 現在 Tohoku University Graduate School of Science Department of Chemistry Associate Professor
- 2016/10 - 2020/03 Japan Science and Technology Agency
- 2014/07 - 2020/03 Tohoku University Graduate School of Science Department of Chemistry Junior Associate Professor
- 2010/02 - 2014/06 Kyoto University Graduate School of Engineering Department of Synthetic Chemistry and Biological Chemistry Assistant Professor
- 2010/04 - 2010/10 日本学術振興会特別研究員(PD) 東京大学大学院医学系研究科 PD
Awards (7):
Association Membership(s) (4):
日本農芸化学会
, 日本ケミカルバイオロジー学会
, 植物調節学会
, 日本化学会
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