Uehara Ryota

ウエハラリヨウタ | Uehara Ryota

Affiliation and department：
Job title：准教授
Homepage URL (1)： https://altair.sci.hokudai.ac.jp/uehara_lab/

Research field (1)： Cell biology

Research keywords (18)： Ploidy , Ploidy , 多倍体 , 一倍体 , Spindle , Motor proteins , Mitosis , Cytokinesis , Centrosome , 細胞質分裂 , endoplasmic reticulum stress , 微小管 , 自己組織化 , 細胞分裂 , 生細胞観察 , 紡錘体 , 中央紡錘体 , 分子モーター

Research theme for competitive and other funds (12)：

2024 - 2028 ゲノム規模のハプロ不全の制御のための「遺伝子量補填」標的の同定
2024 - 2027 染色体倍加が引き起こすがん生体内進化の分子機序
2024 - 2027 4倍体細胞の幾何特性がもたらす分裂制御脆弱性の解明
2019 - 2024 Principle of body malfunctioning through local cell division failure
2021 - 2023 中心体複製チェックポイントの人工合成による安定一倍体細胞の樹立

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Papers (30)：

Sumire Ishida-Ishihara, Kan Yaguchi, Sena Miura, Ryoto Nomura, QiJiao Wang, Koya Yoshizawa, Kimino Sato, Guang Yang, Krisztina Veszelyi, Gabor Banhegyi, et al. Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells. The Journal of biological chemistry. 2024. 107909-107909
Kan Yaguchi, Daiki Saito, Triveni Menon, Akira Matsura, Miyu Hosono, Takeomi Mizutani, Tomoya Kotani, Sreelaja Nair, Ryota Uehara. Haploidy-linked cell proliferation defects limit larval growth in zebrafish. Open biology. 2024. 14. 10. 240126-240126
Saugata Sahu, Koya Yoshizawa, Takahiro Yamamoto, Ryota Uehara, Nobuyuki Tamaoki. Photoswitchable Auxin-Inducible Degron System for Conditional Protein Degradation with Spatiotemporal Resolution. Journal of the American Chemical Society. 2024. 146. 31. 21203-21207
Kazuya Matsuo, Ryota Uehara, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki. Spatiotemporal regulation of CENP-E-guided chromosomes using a fast-relaxing arylazopyrazole photoswitch. Chemical communications (Cambridge, England). 2024
Takahiro Yamamoto, Ryota Uehara. Cell shape instability during cytokinesis in tetraploid HCT116 cells. Biochemical and biophysical research communications. 2023. 678. 39-44

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MISC (1)：

上原亮太, 釜崎とも子, 依田欣哉, 五島剛太. 動物細胞における中央紡錘体の形成・形態制御機構. 日本細胞生物学会大会要旨集. 2014. 66th

Lectures and oral presentations (9)：

A novel link between ploidy level and centrosome homeostasis in mammalian somatic cells
(Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India 2018)
Molecular mechanism of the contractile ring-the plasma membrane interaction during cytokinesis in human cells
(69th JSCB meeting symposium 2017)
Novel link between ploidy level and centrosome homeostasis in mammalian somatic cells
(Cold Spring Harber Asia Meeting “Cilia and Centrosomes” 2017)
動物細胞における中央紡錘体の形成・形態制御機構
(第66回日本細胞生物学会大会シンポジウム 2014)
細胞生物学的手法と数理モデルを用いた細胞質分裂制御の解析
(第6回定量生物学会年会 2013)

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Education (4)：

2003 - 2008 東京大学大学院総合文化研究科広域科学専攻生命環境科学系
2006 - 2006 米国海洋生物学研究所生理学コース
2001 - 2003 The University of Tokyo College of Arts and Sciences Department of Life and Cognitive Sciences
1999 - 2001 The University of Tokyo College of Arts and Sciences

Professional career (1)：

博士(学術) (東京大学大学院総合文化研究科)

Work history (5)：

2017/11 - 現在 Hokkaido Univ. Faculty of Adv. Life Sci. Associate Prof. (PI)
2017/11 - 現在 Hokkaido University Faculty of Advanced Life Science
2013/12 - 2017/10 Hokkaido University
2013/02 - 2013/12 The University of Tokyo
2008/04 - 2013/01 Nagoya University

Awards (3)：

2013/06 - 第65回日本細胞生物学会年会若手優秀発表賞
2012/08 - 米国実験生物学会年会(FASEB meeting)トラベルアウォード
2010/12 - 名古屋大学GCOEシステム生命科学研究若手顕彰

Association Membership(s) (3)：

米国細胞生物学会 , JAPAN SOCIETY FOR CELL BIOLOGY , 日本分子生物学会

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