TAKEI NORIO

タケイノリオ | TAKEI NORIO

Affiliation and department：

Research field (3)： Laboratory animal science , Experimental pathology , Hematology and oncology

Research theme for competitive and other funds (8)：

2023 - 2027 癌・精巣特異的嗅覚受容体を介した癌転移機構の解明と臨床応用
2021 - 2024 Examination of the therapeutic effect on inflammatory bowel disease using HSPB6-positive exosomes derived from amnion-derived MSCs
2021 - 2024 Establishment of the platform for a drug discovery of multiple myeloma by targeting PBK-related signaling pathway
2019 - 2022 Analyses of functional differentiation and interaction of RAMP1,2 and 3 applying the maternal Cas9-based multiple genome editing
2018 - 2021 Elucidation of the mechanism of action of the olfactory receptor involved in cancer-specific metabolism

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Papers (7)：

Masahiro Chiba, Joji Shimono, Takashi Ishio, Norio Takei, Kohei Kasahara, Reiki Ogasawara, Takahide Ara, Hideki Goto, Koh Izumiyama, Satoko Otsuguro, et al. Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas. Blood. 2022. 140. 18. 1951-1963
Akinobu Ota, Ichiro Hanamura, Sivasundaram Karnan, Shingo Inaguma, Norio Takei, Vu Quang Lam, Shohei Mizuno, Jo Kanasugi, Md Wahiduzzaman, Md Lutfur Rahman, et al. Novel Interleukin-6 Inducible Gene PDZ-Binding Kinase Promotes Tumor Growth of Multiple Myeloma Cells. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2020. 40. 8. 389-405
Sakurai T, Kamiyoshi A, Takei N, Watanabe S, Sato M, Shindo T. Bindel-PCR: a novel and convenient method for identifying CRISPR/Cas9-induced biallelic mutants through modified PCR using Thermus aquaticus DNA polymerase. Scientific reports. 2019. 9. 1. 9923
Takei N, Yoneda A, Kosaka M, Sakai-Sawada K, Tamura Y. ERO1α is a novel endogenous marker of hypoxia in human cancer cell lines. BMC cancer. 2019. 19. 1. 510-510
Mizuki Fujii, Akihiro Yoneda, Norio Takei, Kaori Sakai-Sawada, Marina Kosaka, Kenjiro Minomi, Atsuro Yokoyama, Yasuaki Tamura. Endoplasmic reticulum oxidase 1 alpha is critical for collagen secretion from and membrane type 1-matrix metalloproteinase levels in hepatic stellate cells. JOURNAL OF BIOLOGICAL CHEMISTRY. 2017. 292. 38. 15649-15660

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MISC (11)：

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Patents (6)：

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Professional career (1)：

Work history (3)：

Association Membership(s) (2)：

日本ゲノム編集学会 , 日本癌学会

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