KANASEKI TAKAYUKI

カナセキタカユキ | KANASEKI TAKAYUKI

Homepage URL (1)： https://researchmap.jp/kanaseki

Research field (2)： Experimental pathology , Immunology

Research keywords (4)： Immunopeptidomics , Tumor antigen , Cancer Immunotherapy , T cell

Research theme for competitive and other funds (17)：

2024 - 2027 がん予防法開発を目指したがん共通抗原の標的妥当性の検証
2024 - 2027 ネオ抗原特異的T細胞の分子変化に基づく新規免疫チェックポイント分子の探索
2024 - 2027 新しいネオ抗原検出技術による腫瘍特異的CD4+T細胞の機能解析とがん治療応用
2023 - 2026 Identification of oral cancer neoantigens with proteogenomics HLA ligandome analysis
2023 - 2025 新規プロテオゲノミクス技術を応用した真のネオ抗原探索とそのバイオマーカー・治療への応用

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Papers (120)：

Minami Fusagawa, Serina Tokita, Kenji Murata, Tasuku Mariya, Mina Umemoto, Shintaro Sugita, Kazuhiko Matsuo, Yoshihiko Hirohashi, Tsuyoshi Saito, Takayuki Kanaseki, et al. Identification and phenotypic characterization of neoantigen-specific cytotoxic CD4+ T cells in endometrial cancer. Cancer Immunology Research. 2024. (in press)
Serina Tokita, Takayuki Kanaseki, Toshihiko Torigoe. Neoantigen prioritization based on antigen processing and presentation. Frontiers in Immunology. 2024. 15
Serina Tokita, Minami Fusagawa, Satoru Matsumoto, Tasuku Mariya, Mina Umemoto, Yoshihiko Hirohashi, Fumitake Hata, Tsuyoshi Saito, Takayuki Kanaseki, Toshihiko Torigoe. Identification of immunogenic HLA class I and II neoantigens using surrogate immunopeptidomes. Science Advances. 2024. 10. 38
Satoru Matsumoto, Takahiro Tsujikawa, Serina Tokita, Mai Mohamed Bedeir, Kazuhiko Matsuo, Fumitake Hata, Yoshihiko Hirohashi, Takayuki Kanaseki, Toshihiko Torigoe. HLA class II neoantigen presentation for CD4 ⁺ T cell surveillance in HLA class II-negative colorectal cancer. OncoImmunology. 2024. 13. 1
Mina Umemoto, Tasuku Mariya, Yuta Nambu, Mai Nagata, Toshihiro Horimai, Shintaro Sugita, Takayuki Kanaseki, Yuka Takenaka, Shota Shinkai, Motoki Matsuura, et al. Prediction of Mismatch Repair Status in Endometrial Cancer from Histological Slide Images Using Various Deep Learning-Based Algorithms. Cancers. 2024. 16. 10

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MISC (8)：

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Patents (5)：

Lectures and oral presentations (15)：

A cryptic antigen derived from the non-coding RNA PVT1 as a target for T-cell-mediated immunotherapy
(日本癌学会(国際セッション) 2024)
Identification of immunogenic HLA class I and II neoantigens using surrogate immunopeptidomes and characterization of neoantigen-reactive CD4 T cells
(2024)
Rapid identification of immunogenic neoantigens using surrogate immunopeptidomes
(2023)
免疫プロテオゲノミクスによるがん抗原探索
(日本病理学会カンファレンス(シンポジウム) 2023)
臨床的に意義のあるネオアンチゲン探索
(日本がん免疫学会(シンポジウム) 2022)

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Professional career (1)：

Work history (5)：

Committee career (4)：

Awards (2)：

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