Rchr

J-GLOBAL ID：201501051016792798 Update date: May. 17, 2024

DAISUKE MORITO

DAISUKE MORITO

Affiliation and department：
Homepage URL (1)： https://www.proteinlifetime.jp/research/a01-3/

Research field (3)： Cell biology , Pathobiochemistry , Functional biochemistry

Research theme for competitive and other funds (13)：

2023 - 2026 Elucidation of the pathogenesis of moyamoya disease through Endothelial-Smooth Muscle Interaction and RNF213
2022 - 2025 Biology of the Lipid Ubiquitylation
2022 - 2024 Organellar Autophagy and Vascular Disorders
2021 - 2024 Elucidation of moyamoya disease pathophysiology through an interaction of hemodynamics and endothelial cells
2021 - 2023 ユビキチン化異常を起点とする血管障害の統合的理解と創薬

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Papers (15)：

Munechika Sugihara, Daisuke Morito, Shiori Ainuki, Yoshinobu Hirano, Kazutoyo Ogino, Akira Kitamura, Hiromi Hirata, Kazuhiro Nagata. The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets. The Journal of cell biology. 2019. 218. 3. 949-960
Shoshiro Hirayama, Munechika Sugihara, Daisuke Morito, Shun-ichiro Iemura, Tohru Natsume, Shigeo Murata, Kazuhiro Nagata. Nuclear export of ubiquitinated proteins via the UBIN-POST system. Proceedings of the National Academy of Sciences of the United States of America. 2018. 115. 18. E4199-E4208
Yuri Kotani, Daisuke Morito, Kenshiro Sakata, Shiori Ainuki, Munechika Sugihara, Tomohisa Hatta, Shun-ichiro Iemura, Seiji Takashima, Tohru Natsume, Kazuhiro Nagata. Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor. SCIENTIFIC REPORTS. 2017. 7
Yuri Kotani, Daisuke Morito, Satoru Yamazaki, Kazutoyo Ogino, Koichi Kawakami, Seiji Takashima, Hiromi Hirata, Kazuhiro Nagata. Neuromuscular regulation in zebrafish by a large AAA plus ATPase/ubiquitin ligase, mysterin/RNF213. SCIENTIFIC REPORTS. 2015. 5
Janine Kirstein, Daisuke Morito, Taichi Kakihana, Munechika Sugihara, Anita Minnen, Mark S. Hipp, Carmen Nussbaum-Krammer, Prasad Kasturi, F. Ulrich Hartl, Kazuhiro Nagata, et al. Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. EMBO JOURNAL. 2015. 34. 18. 2334-2349

ｍore...

MISC (1)：

A novel giant ATPase/ubiquitin ligase mysterin regulates proper angiogenesis and is involved in Moyamoya disease. 2010. 62回. 111-111

Patents (2)：

モヤモヤ病関連遺伝子及びその利用
もやもや病を処置することに用いるための、または脂肪代謝を促進することに用いるための医薬組成物

Education (4)：

2001 - 2008 京都大学大学院理学研究科博士後期課程(修了)
1999 - 2001 京都大学大学院理学研究科博士前期課程(修了)
1994 - 1999 Kyoto University Faculty of Science
1991 - 1994 Rakunan High School

Professional career (1)：

博士(理学) (京都大学)

Work history (5)：

2018/06 - 現在 Showa University School of Medicine
2017/04 - 現在 Kyoto University Faculty of Medicine
2014/04 - 2018/05 Kyoto Sangyo University Faculty of Life Sciences
2010/04 - 2014/03 Kyoto Sangyo University Faculty of Life Sciences
2008/04 - 2010/03 Kyoto University Institute for Frontier Medical Sciences

Committee career (3)：

2021/07 - 2023/06 日本学術振興会特別研究員等審査会専門委員
2021/07 - 2023/06 日本学術振興会卓越研究員候補者選考委員会書面審査員
2021/07 - 2023/06 日本学術振興会国際事業委員会書面審査員・書面評価員

Awards (4)：

2016/05 - 日本生化学会近畿支部奨励賞
2014/05 - 日本生化学会近畿支部優秀発表賞
2010/09 - 特定領域研究「タンパク質の社会」国際会議最優秀ポスター賞
2010/06 - 日本細胞生物学会若手優秀発表賞

Association Membership(s) (4)：

The American Society for Cell Biology , 日本分子生物学会 , 日本生化学会 , 日本細胞生物学会

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