Rchr
J-GLOBAL ID：201501058458944788   Update date: Jun. 22, 2024

Tatsufumi Mori

モリ タツフミ | Tatsufumi Mori
Affiliation and department：
Kindai University Life Science Research Institute

About Kindai University Life Science Research Institute


Research field  (2)： Orthopedics ,  Developmental biology
Research keywords  (9)： MSC ,  再生医療 ,  多能性幹細胞 ,  体外培養 ,  発生工学 ,  卵成熟 ,  顕微授精 ,  胚発生 ,  卵胞培養
Research theme for competitive and other funds  (2)：
  • 2021 - 2024 Creation of mesenchymal stem cells using transdifferentiation and undifferentiated induction by the transcription factor TWIST1
  • 2019 - 2021 Functional elucidation of TWIST 1 in stemness of Mesenchymal stem cells
Papers (13)：
  • Kensuke Toriumi, Yuta Onodera, Toshiyuki Takehara, Tatsufumi Mori, Joe Hasei, Kanae Shigi, Natsumi Iwawaki, Toshifumi Ozaki, Masao Akagi, Mahito Nakanishi, et al. LRRC15 expression indicates high level of stemness regulated by TWIST1 in mesenchymal stem cells. iScience. 2023. 26. 7. 106946-106946
  • Tatsufumi Mori, Masatsugu Igarashi, Yuta Onodera, Toshiyuki Takehara, Maki Itokazu, Takeshi Teramura. Fibrinogen supports self-renewal of mesenchymal stem cells under serum-reduced condition through autophagy activation. Biochemical and Biophysical Research Communications. 2023
  • Maki Itokazu, Yuta Onodera, Tatsufumi Mori, Shinji Inoue, Kotaro Yamagishi, Akihiro Moritake, Natsumi Iwawaki, Kanae Shigi, Toshiyuki Takehara, Yuji Higashimoto, et al. Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2. The Journal of biological chemistry. 2022. 298. 7. 102098-102098
  • Tatsufumi Mori, Yuta Onodera, Maki Itokazu, Toshiyuki Takehara, Kanae Shigi, Natsumi Iwawaki, Masao Akagi, Takeshi Teramura. Depletion of NIMA-related kinase Nek2 induces aberrant self-renewal and apoptosis in stem/progenitor cells of aged muscular tissues. Mechanisms of ageing and development. 2022. 201. 111619-111619
  • Takatoshi Tsujimoto, Tatsufumi Mori, Kei Houri, Yuta Onodera, Toshiyuki Takehara, Kanae Shigi, Shinichi Nakao, Takeshi Teramura, Kanji Fukuda. miR-155 Inhibits Mitophagy Through Suppression of BAG5, a Partner Protein of PINK1. Biochem Biophys Res Commun. 2020. 523. 3. 707-712
ｍore...
MISC (12)：
  • 鳥海賢介, 小野寺勇太, 森樹史, 糸数万紀, 信貴香苗, 江川健太郎, 竹原俊幸, 赤木將男, 寺村岳士. LRRC15 is a cell membranous protein indicates high level of stemness and therapeutic potentials regulated by TWIST1 in MSCs. 日本軟骨代謝学会プログラム・抄録集. 2023. 35th
  • 森樹史, 小野寺勇太, 信貴香苗, 糸数万紀, 岩脇菜摘, 竹原俊幸, 赤木將男, 寺村岳士. NINA-related kinase(Nek2)は加齢マウスでの筋衛星細胞の減少に関与する. 日本再生医療学会総会(Web). 2022. 21st
  • 小野寺勇太, 信貴香苗, 糸数万紀, 森樹史, 岩脇菜摘, 竹原俊幸, 福田寛二, 福田寛二, 寺村岳士. 核小体タンパク質LYARは骨髄間葉系幹細胞の脂肪分化を制御する. 日本再生医療学会総会(Web). 2022. 21st
  • 糸数万紀, 小野寺勇太, 森樹史, 岩脇菜摘, 信貴香苗, 信貴香苗, 竹原俊幸, 福田寛二, 福田寛二, 寺村岳士. 加齢脂肪組織由来エクソソームはmiRNA let7d-Hmga2経路で筋衛星細胞の細胞増殖を阻害する. 日本再生医療学会総会(Web). 2022. 21st
  • 森樹史, 小野寺勇太, 大高真奈美, 竹原俊幸, 中西真人, 寺村岳士. 転写因子Twist1による間葉系幹細胞の幹細胞性制御. 日本再生医療学会総会(Web). 2021. 20th
ｍore...
Lectures and oral presentations  (7)：
  • フィブリノーゲンは培養機材上へのbasic-FGFの安定化を誘導し、血清低減環境下での 間葉系幹細胞の増殖促進に寄与する
  • NINA-related kinase (Nek2) は加齢マウスでの筋衛星細胞の減少に関与する
  • NINA-related kinase (NEK2)は加齢マウスでの筋衛星細胞の減少に関与する
    (第21回日本再生医療学会総会)
  • 間葉系幹細胞のステムネスにおけるTWIST1の機能解明
    (第19回 日本再生医療学会総会)
  • TAK1 regulates proliferation of BMMSCs through activation of Yes-associated protein (Yap1)
ｍore...
Professional career (1)：
  • 工学修士 (近畿大学生物理工学研究科)
Work history (1)：
  • 2015/04 - 2018 Kindai University Life Science Research Institute
Association Membership(s) (5)：
the Japanese Society of Cartilage Metabolism ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  JAPAN SOCIETY FOR REPRODUCTIVE MEDICINE ,  Japanese Society of Mammalian Ova Research ,  JAPAN SOCIETY OF FERTILIZATION AND IMPLANTATION
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