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J-GLOBAL ID：201501058521570400   Update date: Sep. 30, 2024

Nakamura Takashi

ナカムラ タカシ | Nakamura Takashi
Affiliation and department：
Tohoku University Graduate School of Dentistry Dentistry Oral Biology Dental Pharmacology

About Tohoku University Graduate School of Dentistry Dentistry Oral Biology Dental Pharmacology


Job title： Associate Professor
Research field  (3)： Oral medicine ,  Regenerative dentistry and dental engineering ,  Oral medicine
Research keywords  (18)： Molecular biology ,  Endocrinology ,  Developmental biology ,  Cell biology ,  gender difference ,  栄養学 ,  epiprofin ,  Pharmacology ,  tooth development ,  Morphogenesis ,  enamel ,  cancer ,  Organogenesis ,  vitaminD ,  Salivary gland ,  cell cycle ,  molecular biology ,  parathyroid
Research theme for competitive and other funds  (14)：
  • 2021 - 2025 唾液腺発生における神経-器官相互作用の分子機構の解明と機能再生技術への応用
  • 2021 - 2024 エピプロフィンによる上皮間葉転換制御機構を応用したがん治療と器官原器複製術の開発
  • 2020 - 2023 Study on neural mechanism of swallowing by imaging
  • 2020 - 2023 Elucidation of voltage-gated calcium channel function in nonexcitatory cells based on clinical genomic studies
  • 2018 - 2020 Controlling of organ morphology by anchor proteins in regenerative organogenesis
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Papers (114)：
  • Lucia Jiménez-Rojo, Susana de Vega, Gaskon Ibarretxe, Takashi Nakamura, Fernando J Unda. Disrupted odontoblast differentiation and dentin dysplasia in Epiprofin-deficient mice. The International journal of developmental biology. 2024. 68. 1. 19-24
  • Yuta Chiba, Keigo Yoshizaki, Hiroshi Sato, Tomoko Ikeuchi, Craig Rhodes, Mitsuki Chiba, Kan Saito, Takashi Nakamura, Tsutomu Iwamoto, Aya Yamada, et al. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 4. e22861
  • Aya Yamada, Keigo Yoshizaki, Kan Saito, Masaki Ishikawa, Yuta Chiba, Seira Hoshikawa, Mitsuki Chiba, Ryoko Hino, Yuriko Maruya, Hiroshi Sato, et al. GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation. Journal of oral biosciences. 2022. 64. 4. 400-409
  • Yuki Shindo, Hannah M. Nakamura, Junichi Nakai, Minoru Wakamori, Takashi Nakamura. A parasympathetic neurotransmitter induces myoepithelial cell differentiation during salivary gland development. Experimental Cell Research. 2022. 416. 1. 113137-113137
  • Xinchao Miao, Kunimichi Niibe, Yunyu Fu, Maolin Zhang, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa. Epiprofin Transcriptional Activation Promotes Ameloblast Induction From Mouse Induced Pluripotent Stem Cells via the BMP-Smad Signaling Axis. Frontiers in Bioengineering and Biotechnology. 2022. 10
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MISC (51)：
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Books (3)：
  • 新規転写因子エピプロフィンによる副甲状腺ホルモン発現制御
    2014
  • 小児歯科で取り組む再生医療
    日本小児医事出版社 2010
  • 歯の再生-歯の発生生物学から歯の再生研究まで
    真興交易医書出版部 2008
Lectures and oral presentations  (42)：
  • 100年つかえる丈夫な永久歯には、 おなかの中にいるときの栄養が関係しているの?
    (至学館大学公開講座 2024年度 2024)
  • Elucidation of neuronal-epithelial communication in murine submandibular development
    (Korean Division of theInternational Association for Dental Research 2022)
  • Roles of Epiprofin in dental epithelial cell differentiation
    (IOHS 2019 2019)
  • 副甲状腺ホルモンの転写制御に関わるエピプロフィンの役割
    (第36回内分泌代謝学サマーセミナー 2018)
  • The effect of three-dimensional culture on the ameloblastic differentiation of dental epithelial cells
    (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 2017)
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Education (2)：
  • - 1998 Osaka University Graduate School, Division of Dental Research 口腔外科学
  • - 1994 Hiroshima University Faculty of Dentistry 歯学科
Professional career (1)：
  • 歯学 (Osaka University)
Work history (4)：
  • 2007/10 - 2009/03 Thomas Jefferson University
  • 2004/09 - 2007/09 National Institute of Dental and Craniofacial Research 職員研究員
  • 1999/11 - 2004/08 National Institute of Dental and Craniofacial Resarch Visiting Fellow
  • 1998/06 - 1999/10 関西ろうさい病院
Awards (6)：
  • 2018/02 - 第39回東北骨代謝・骨粗鬆症研究会 優秀演題賞 新規転写因子エピプロフィンによる副甲状ホルモン発現制御機構
  • 2010/05/20 - 日本小児歯科学会 小児歯科学会優秀発表賞
  • 2007/10 - National Institute of Dental and Craniofacial Research NIDCR Incentive Award
  • 2006/11 - National Institute of Dental and Craniofacial Research NIDCR Individual Cash Award
  • 2005/01 - National Institutes of Health NIH Fellows Award for Research Excellence
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Association Membership(s) (6)：
The Japanese Pharmacological Society ,  THE JAPANESE SOCIETY OF PEDIATRIC DENTISTRY ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE ASSOCIATION FOR ORAL BIOLOGY
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