Takeshi Niinuma

ニイヌマタケシ | Takeshi Niinuma

Homepage URL (1)： https://kaken.nii.ac.jp/d/r/60708113.ja.html

Research field (1)： Gastroenterology

Research theme for competitive and other funds (6)：

2022 - 2025 大腸低分化腺がんにおけるSAA1の分子機能解明と診断・治療への応用
2022 - 2025 DOT1L阻害によるインターフェロン応答の機序解明とがん免疫療法への応用
2021 - 2024 がん細胞のインターフェロンシグナルを制御する長鎖noncoding RNAの解析
2018 - 2021 Comprehensive analysis of epigenetic alteration and lncRNA involved to colon cancer development
2016 - 2018 Epigenetic dysregulation of noncoding RNAs in gastrointestinal cancer progression

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Papers (79)：

Hironori Aoki, Akira Takasawa, Eiichiro Yamamoto, Takeshi Niinuma, Hiro-O Yamano, Taku Harada, Toshiyuki Kubo, Akira Yorozu, Hiroshi Kitajima, Kazuya Ishiguro, et al. Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas. BMC gastroenterology. 2024. 24. 1. 91-91
Shohei Sekiguchi, Akira Yorozu, Fumika Okazaki, Takeshi Niinuma, Akira Takasawa, Eiichiro Yamamoto, Hiroshi Kitajima, Toshiyuki Kubo, Yui Hatanaka, Koyo Nishiyama, et al. ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma. Cancers. 2023. 15. 17
Hiroshi Kitajima, Reo Maruyama, Takeshi Niinuma, Eiichiro Yamamoto, Akira Takasawa, Kumi Takasawa, Kazuya Ishiguro, Akihiro Tsuyada, Ryo Suzuki, Gota Sudo, et al. TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells. Cell Death & Disease. 2023. 14. 7
Ayano Yoshido, Gota Sudo, Akira Takasawa, Hironori Aoki, Hiroshi Kitajima, Eiichiro Yamamoto, Takeshi Niinuma, Taku Harada, Toshiyuki Kubo, Hajime Sasaki, et al. Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers. Journal of gastroenterology and hepatology. 2022. 38. 2. 301-310
Akira Yorozu, Shohei Sekiguchi, Akira Takasawa, Fumika Okazaki, Takeshi Niinuma, Hiroshi Kitajima, Eiichiro Yamamoto, Masahiro Kai, Mutsumi Toyota, Yui Hatanaka, et al. CXCL12 is expressed by skeletal muscle cells in tongue oral squamous cell carcinoma. Cancer medicine. 2022. 12. 5. 5953-5963

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MISC (65)：

Shohei Sekiguchi, Akira Yorozu, Eiichiro Yamamoto, Takeshi Niinuma, Akira Takasawa, Gota Sudo, Kazushige Koike, Yui Hatanaka, Ayano Yoshido, Hiroshi Kitajima, et al. Analysis of AEBP1 in the microenvironment of head and neck squamous cell carcinoma. CANCER SCIENCE. 2022. 113. 1506-1506
Hideaki Takahashi, Chiaki Okuse, Norie Yamada, Takeshi Niinuma, Masahiro Kai, Hideki Wakasugi, Noriyuki Akutsu, Hiroshi Yotsuyanagi, Michihiro Suzuki, Hiromu Suzuki, et al. LOW EXPRESSION OF miRNA-199-5p AND miRNA-374 CAN PREDICT THE INCIDENCE OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH CHRONIC HEPATITIS B AFTER ADMINISTRATION OF NUCLEOSIDE ANALOG. HEPATOLOGY. 2021. 74. 656A-657A
青木敬則, 山本英一郎, 高澤啓, 新沼猛, 山野泰穂, 萬顕, 北嶋洋志, 甲斐正広, 小山内誠, 仲瀬裕志, et al. SMOC1の大腸腫瘍診断マーカーとしての臨床的有用性の検討. 日本癌学会総会記事. 2021. 80回. [P14-4]
青木敬則, 山本英一郎, 高澤啓, 新沼猛, 山野泰穂, 萬顕, 北嶋洋志, 甲斐正広, 小山内誠, 仲瀬裕志, et al. SMOC1の大腸腫瘍診断マーカーとしての臨床的有用性の検討. 日本癌学会総会記事. 2020. 79回. PJ14-1
鈴木拓, 新沼猛, 北嶋洋志, 山本英一郎, 甲斐正広, 高橋秀明, 伊東文生. 臨床医学の最新情報がんのnon-coding RNA異常およびエピゲノム異常の解析とその応用. 電気泳動. 2018. 62. Suppl. s23-s23

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Work history (1)：

2021/06 - 現在 Sapporo Medical University School of Medicine

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