Kitai Yuichi

Affiliation and department：

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (3)：がん免疫 , 細胞死 , 自然免疫

Research theme for competitive and other funds (11)：

2022 - 2026 エネルギー代謝に着目した核医学イメージングによるがん微小環境評価
2023 - 2025 ポストコロナの感染症・がん予防に向けての貪食促進型赤血球ワクチンの創製
2021 - 2024 Development of novel PROTACs that activates antitumor immunity
2019 - 2022 Study of signaling pathways for treatment of immune/allergic diseases
2019 - 2021 がん免疫の活性化を誘導する新規薬剤の開発

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Papers (52)：

Kota Kagohashi, Yuto Sasaki, Kiyotaka Ozawa, Takuya Tsuchiya, Shoya Kawahara, Kodai Saitoh, Michiko Ichii, Jun Toda, Yasuyo Harada, Masato Kubo, et al. Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation. The Journal of Immunology. 2024
Jun-Ichi Kashiwakura, Shoya Kawahara, Iori Inagaki, Kyosuke Inui, Kodai Saitoh, Kota Kagohashi, Yuto Sasaki, Fuki Kobayashi, Yuichi Kitai, Ryuta Muromoto, et al. STAP-2 negatively regulates BCR-mediated B cell activation by recruiting tyrosine-protein kinase CSK to LYN. FEBS letters. 2023. 597. 19. 2433-2445
Yuto Sasaki, Kodai Saitoh, Kota Kagohashi, Toyoyuki Ose, Shoya Kawahara, Yuichi Kitai, Ryuta Muromoto, Yuichi Sekine, Michiko Ichii, Akihiko Yoshimura, et al. STAP-2-Derived Peptide Suppresses TCR-Mediated Signals to Initiate Immune Responses. The Journal of Immunology. 2023
Takuro Kameda, Kotaro Shide, Ayako Kamiunten, Yasunori Kogure, Daisuke Morishita, Junji Koya, Yuki Tahira, Keiichi Akizuki, Takako Yokomizo-Nakano, Sho Kubota, et al. CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma. Communications Biology. 2022. 5. 1
Taiga Maemoto, Yuichi Kitai, Runa Takahashi, Haruka Shoji, Shunsuke Yamada, Shiho Takei, Daiki Ito, Ryuta Muromoto, Jun-Ichi Kashiwakura, Haruka Handa, et al. A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling. The Journal of biological chemistry. 2022. 299. 1. 102724-102724

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MISC (17)：

松田正, 室本竜太, 鍛代悠一, 織谷健司. 【IL-6阻害療法の基礎と臨床】IL-6とそのシグナル伝達系の分子基盤. リウマチ科. 2023. 69. 1. 1-12
西東秀晃, 一井倫子, 戸田淳, 鍛代悠一, 室本竜太, 柏倉淳一, 斎藤宏大, 横田貴史, 柴山浩彦, 松田正, et al. Signal Transducing Adaptor Protein(STAP)-2はGVHD増悪に関与する. 日本血液学会学術集会抄録(Web). 2020. 82nd
山田駿介, 鍛代悠一, 室本竜太, 柏倉淳一, 松田正. トポテカンの新規標的である60SリボソームタンパクRPLAはDAMPsの放出およびがん免疫の活性化に関与する. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
Jun Toda, Michiko Ichii, Hirohiko Shibayama, Hideaki Saito, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Kenji Oritani, et al. Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia Stem Cells. BLOOD. 2018. 132
Jun Toda, Michiko Ichii, Hirohiko Shibayama, Hideaki Saito, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Kenji Oritani, et al. Role of Signal Transducing Adaptor Protein (STAP) Family in Chronic Myelogenous Leukemia. BLOOD. 2017. 130

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Professional career (1)：

医学博士 (大阪大学)

Work history (1)：

2015/04 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences

Awards (1)：

2020 - 日本薬学会北海道支部 2020年度奨励賞

Association Membership(s) (4)：

日本Cell Death学会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN , JAPANESE SOCIETY FOR IMMUNOLOGY

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