Yasukochi Yoshiki

ヤスコウチヨシキ | Yasukochi Yoshiki

Affiliation and department：
Homepage URL (1)： http://www3.kmu.ac.jp/genome/index.html

Research field (4)： Genetics , Applied anthropology , Physical anthropology , Evolutionary biology

Research keywords (10)：トランスクリプトーム , 分子進化 , GWAS , 低圧低酸素 , 環境適応 , 人類進化 , 遺伝子重複 , 遺伝的多型 , 基質特異性 , 偽遺伝子化

Research theme for competitive and other funds (7)：

2024 - 2028 Elucidation of the Mechanism of Rheumatoid Arthritis Development under Hypoxic Conditions: Perspectives on Adaptation and Disruption
2018 - 2020 アンデス高地集団の低圧低酸素環境への遺伝的・生理的適応に関する包括的研究
2018 - 2020 低圧低酸素および寒冷環境に対する循環調節系の適応反応とその多型性
2017 - 2020 ビッグデータ駆動型科学のための仮説生成・検証法開発と材料,生物,医療分野での実証
2016 - 2018 現代人の高地適応に関連する旧人類ハプロタイプの進化の解明

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Papers (63)：

Chisato Ohe, Takashi Yoshida, Mahul B. Amin, Naho Atsumi, Junichi Ikeda, Kazuho Saiga, Yuri Noda, Yoshiki Yasukochi, Riuko Ohashi, Haruyuki Ohsugi, et al. Development and validation of a vascularity-based architectural classification for clear cell renal cell carcinoma: correlation with conventional pathological prognostic factors, gene expression patterns, and clinical outcomes. Modern Pathology. 2022. 35. 6. 816-824
Chisato Ohe, Takashi Yoshida, Mahul B Amin, Naho Atsumi, Junichi Ikeda, Kazuho Saiga, Yuri Noda, Yoshiki Yasukochi, Riuko Ohashi, Haruyuki Ohsugi, et al. Correction to: Development and validation of a vascularity-based architectural classification for clear cell renal cell carcinoma: correlation with conventional pathological prognostic factors, gene expression patterns, and clinical outcomes. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2022. 35. 5. 708-708
Kazuho Saiga, Chisato Ohe, Takashi Yoshida, Haruyuki Ohsugi, Junichi Ikeda, Naho Atsumi, Yuri Noda, Yoshiki Yasukochi, Koichiro Higasa, Hisanori Taniguchi, et al. PBRM1 Immunohistochemical Expression Profile Correlates with Histomorphological Features and Endothelial Expression of Tumor Vasculature for Clear Cell Renal Cell Carcinoma. Cancers. 2022. 14. 4
Chisato Ohe, Takashi Yoshida, Junichi Ikeda, Toyonori Tsuzuki, Riuko Ohashi, Haruyuki Ohsugi, Naho Atsumi, Ryosuke Yamaka, Ryoichi Saito, Yoshiki Yasukochi, et al. Histologic-Based Tumor-Associated Immune Cells Status in Clear Cell Renal Cell Carcinoma Correlates with Gene Signatures Related to Cancer Immunity and Clinical Outcomes. Biomedicines. 2022. 10. 2
Derivation and molecular phylogenetic analysis of "bear's hands" in Takachiho Town, Miyazaki Prefecture : DNA analysis of Japanese black bear on the Sobo Mountain Range, Kyushu Is. 哺乳類科学 = Mammalian science. 2022. 62. 1. 3-10

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MISC (8)：

安河内彦輝, 西村貴孝, 大西真由美, 西原三佳, UGARTE Juan, 福田英輝, 青柳潔. 全ゲノム解析による南米ボリビア集団の高地適応遺伝子の探索. 日本登山医学会学術集会プログラム・抄録集. 2021. 41st
安河内彦輝, 西村貴孝, 大西真由美, 西原三佳, JUAN Ugarte, 福田英輝, 青柳潔. アンデス高地集団のEGLN1ハプロタイプがヘモグロビン濃度に与える影響. 日本遺伝学会大会プログラム・予稿集. 2020. 92nd
Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, et al. Identification of six polymorphisms as novel susceptibility loci for ischemic or hemorrhagic stroke by exome-wide association studies. International journal of molecular medicine. 2017. 39. 6. 1477-1491
Lau Quintin, Yoshiki Yasukochi, Yoko Satta. Further investigations of co-evolution of HLA and pathogens. GENES & GENETIC SYSTEMS. 2014. 89. 6. 277-277
Yoshiki Yasukochi, Yoko Satta. Estimation for the intensity of natural selection of HLA loci on the basis of newly available nucleotide sequences. GENES & GENETIC SYSTEMS. 2013. 88. 6. 383-383

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Books (4)：

新編生理人類士入門
国際文献社 2022
Cardiovascular Genetics and Genomics: Principles and Clinical Practice
Springer International Publishing 2018 ISBN:9783319661124
生理人類学士入門
国際文献社 2017
『人間科学の百科事典』
丸善出版 2015 ISBN:9784621088302

Lectures and oral presentations (69)：

本邦のうつ病患者と健常者サンプルを用いたゲノムワイド関連解析(GWAS)
(第19回日本うつ病学会総会 2022)
Effect of EGLN1 genetic polymorphisms on hemoglobin concentration in Andean highlanders
(第42回日本登山医学会学術集会 2022)
イモリ脊髄再生におけるトランスクリプトーム解析 -イモリから学ぶ再生原理-
(第127回日本解剖学会総会・全国学術集会 2022)
イモリ脊髄再生におけるトランスクリプトーム解析 -イモリから学ぶ再生原理-
(第21回日本再生医療学会総会 2022)
メラトニン受容体遺伝子近傍の一塩基多型が模擬的夜勤による概日リズムの位相後退に及ぼす影響
(第28回日本時間生物学会学術大会 2021)

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Professional career (1)：

PhD (Kyushu University)

Work history (7)：

2021/08 - 現在 Kansai Medical University Department of Genome Analysis, Institute of Biomedical Science
2016/11 - 2021/07 Mie University Department of Human Functional Genomics, Advanced Science Research Promotion Center, Organization for the Promotion of Regional Innovation Assistant Professor
2016/02 - 2016/10 Mie University Life Science Research Center
2015/10 - 2016/01 The University of Tokyo Graduate School of Science JSPS research fellow (PD)
2014/04 - 2014/09 University of Tsukuba Faculty of Medicine JSPS research fellow (PD)

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Committee career (1)：

2013 - 現在日本生理人類学会評議員

Awards (5)：

2022/06 - 日本登山医学会日本登山医学会2021年度論文奨励賞
2021/02 - Journal of Physiological Anthropology Best Reviewer Award 2020
2019/06 - Japan Society of Physiological Anthropology Best Paper Award for Young Researchers Association of EGLN1 genetic polymorphisms with SpO2 responses to acute hypobaric hypoxia in a Japanese cohort.
2014/11 - Japan Society of Physiological Anthropology Best Presentation Award Genetic evidence for contribution of human evolution to genetic polymorphism of erythrocyte binding molecule EBA-175 in Plasmodium falciparum
2010/09 - The Genetic Society of Japan Best Papers Award Study on evolutionary origin and process of human metabolic system against drugs and chemicals: Molecular evolution of CYP2D subfamily in primates

Association Membership(s) (6)：

Japanese Society of Mountain Medicine , The Society for Molecular Biology and Evolution , SOCIETY OF EVOLUTIONARY STUDIES, JAPAN , THE GENETICS SOCIETY OF JAPAN , JAPAN SOCIETY OF PHYSIOLOGICAL ANTHROPOLOGY , The Anthropological Society of Nippon

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