Rchr
J-GLOBAL ID：201501081538096585   Update date: Feb. 29, 2024

Ohba Kenji

オオバ ケンジ | Ohba Kenji
Affiliation and department：
Jichi Medical University Center for Molecular Medicine, Division of Genetic Therapeutics

About Jichi Medical University Center for Molecular Medicine, Division of Genetic Therapeutics


Homepage URL  (1)： https://www.jichi.ac.jp/genetherapy/
Research field  (10)： Tumor diagnostics and therapeutics ,  Medical biochemistry ,  Genomics ,  Cell biology ,  Molecular biology ,  Immunology ,  Pathobiochemistry ,  Physiology ,  Tumor biology ,  Virology
Research keywords  (6)： Genetic Therapy ,  Immunology ,  Oncology ,  Molecular biology ,  Cell competition ,  Virology
Research theme for competitive and other funds  (7)：
  • 2023 - 2028 次世代医療を目指した再生・細胞医療・遺伝子治療研究開発拠点 (中核拠点)
  • 2023 - 2026 分子特異的DNAアプタマー修飾で細胞特異性を改良した次世代型分子特異的アデノ随伴ウイルス(Apt-AAV)ベクター基盤の研究開発
  • 2020 - 2024 Collaboration for production of AAV vectors
  • 2021 - 2024 異常細胞のMHC-Iシグナルにより惹起される上皮細胞の免疫細胞様機能
  • 2020 - 2023 アデノ随伴ウイルスベクターの粒子形成と感染機構の解析
Show all
Papers (34)：
  • Yuka Hayashi, Yoshihide Sehara, Ryota Watano, Kenji Ohba, Yuki Takayanagi, Yoshio Sakiyama, Kazuhiro Muramatsu, Hiroaki Mizukami. Therapeutic strategy for Fabry disease by intravenous administration of adeno-associated virus 9 in a symptomatic mouse model. Human Gene Therapy. 2024
  • Kenji Ohba, Hiroaki Mizukami. Protocol for producing an adeno-associated virus vector by controlling capsid expression timing. STAR Protocols. 2023. 4. 4. 102542-102542
  • Yuka Hayashi, Yoshihide Sehara, Ryota Watano, Kenji Ohba, Yuki Takayanagi, Kazuhiro Muramatsu, Yoshio Sakiyama, Hiroaki Mizukami. Therapeutic strategy for Fabry disease by intravenous administration of adeno-associated virus 2 or 9 in α-galactosidase A-deficient mice. The Journal of Gene Medicine. 2023. e3560
  • Kenji Ohba, Yoshihide Sehara, Tatsuji Enoki, Junichi Mineno, Keiya Ozawa, Hiroaki Mizukami. Adeno-associated virus vector system controlling capsid expression improves viral quantity and quality. iScience. 2023. 26. 4. 106487-106487
  • Shiyu Ayukawa, Nagisa Kamoshita, Jun Nakayama, Ryohei Teramoto, Novalia Pishesha, Kenji Ohba, Nanami Sato, Kei Kozawa, Hikari Abe, Kentaro Semba, et al. Epithelial cells remove precancerous cells by cell competition via MHC class I-LILRB3 interaction. Nature Immunology. 2021. 22. 11. 1391-1402
ｍore...
MISC (29)：
ｍore...
Patents (2)：
  • Efficient AAV vector production system
  • A Method For Diagnosis Of Hpv-related Non-genital Cancers Using PCR
Books (2)：
  • The development of efficient adeno-associated virus vector production system for gene therapy
    Japan Bioindustry Association 2023
  • HIV感染症における治療と研究
    最新医学 2005
Lectures and oral presentations  (45)：
  • 遺伝子治療の発展を目指した次世代AAVベクターシステムの開発
    (タカラバイオ株式会社 社内招待講演 2023)
  • Efficient adeno-associated virus vector production system through controlling capsid expression timing
    (2023)
  • キャプシドの発現タイミングを調整した効率良いアデノ随伴ウイルスベクター産生システム
    (第21回自治医科大学シンポジウム 2023)
  • Novel adeno-associated virus (AAV) vector production system for gene therapy
    (The 69th Annual Meeting of the Japanese Society for Virology 2022)
  • 変異細胞または正常/変異細胞の境界を認識する膜表面分子の探索
    (第5回 新学術領域班会議ー細胞競合ー 2018)
ｍore...
Education (3)：
  • 2004 - 2008 Tokyo Medical and Dental University Graduate School of Medical and Dental Science Doctral Program for Medical and Dental Science (Medical Doctor Course)
  • 2002 - 2004 Yokohama-city University Graduate School of Medicine Master Course for Medical Science
  • 1998 - 2002 Rikkyo University College of Science Department of Life Science
Professional career (1)：
  • Ph.D. (Tokyo Medical and Dental University)
Work history (5)：
  • 2015/03 - 2018/10 Hokkaido University Division of Molecular Oncology, Institute for Genetic Medicine Project Assistant Professor
  • 2010/04 - 2015/03 National University of Singapore Yong Loo Lin School of Medicine, Department of Microbiology Research Fellow
  • 2008/04 - 2010/03 National Institute of Infectious Diseases AIDS Research Center Postdoctoral Fellow
  • 2004/04 - 2008/03 Tokyo Medical and Dental University School of Medicine Ph.D.
  • 2002/04 - 2004/03 Yokohama City University School of Medicine Master
Awards (2)：
  • 2023 - 自治医科大学 第21回自治医科大学シンポジウム 優秀賞
  • 2023 - 公益財団法人 武田科学振興財団 医学系研究助成
Association Membership(s) (5)：
Japan Society of Gene and Cell Therapy ,  American Society of Gene & Cell Therapy ,  International Society on Aptamers ,  日本ウイルス学会 ,  The Molecuar Biology Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM