Yuki Kambe

カンベユウキ | Yuki Kambe

Affiliation and department：
Job title：講師
Homepage URL (1)： http://www.kufm.kagoshima-u.ac.jp/~pharmaco/

Research field (2)： Pharmacology , Neuroscience - general

Research keywords (12)：乳酸 , 遺伝子組み換えマウス , cre-loxP , shRNA , アデノ随伴ウイルス , アストロサイト , PACAP , 糖代謝 , 包括脳ネットワーク , 脳神経疾患 , ミトコンドリア , シグナル伝達

Research theme for competitive and other funds (20)：

2024 - 2027 慢性疼痛が惹起する不安障害への視床下部室傍核PACAP-モノアミンシグナルの関与の解明
2023 - 2026 大脳皮質視覚野臨界期の神経可塑性における乳酸代謝の寄与の解明
2022 - 2025 発達期の神経活動レベル調節による大脳半球間投射制御の解明
2020 - 2023 Pathophysiological significance of neuron-astrocyte implication of PACAP on stress-induced emotional disorder
2020 - 2023 腹内側核PACAP発現細胞の双方向性摂食調節メカニズムの解明と新規抗肥満薬の開発

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Papers (56)：

Thi Thu Nguyen, Kohei Hashiguchi, James A Waschek, Atsuro Miyata, Yuki Kambe. The pivotal role of PACAP/PAC1R signaling from the anterior insular cortex to the locus coeruleus on anxiety-related behaviors of mice. Neurochemistry international. 2024. 180. 105879-105879
Yusuke Nasu, Abhi Aggarwal, Giang N. T. Le, Camilla Trang Vo, Yuki Kambe, Xinxing Wang, Felix R. M. Beinlich, Ashley Bomin Lee, Tina R. Ram, Fangying Wang, et al. Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging. Nature Communications. 2023
Jun Kaminosono, Yuki Kambe, Akihide Tanimoto, Tomoyuki Kuwaki, Akira Yamashita. The physiological response during optogenetic-based cardiac pacing in awake freely moving mice. Frontiers in physiology. 2023. 14. 1130956-1130956
Yuki Kambe, Masafumi Youkai, Kohei Hashiguchi, Yoshimune Sameshima, Ichiro Takasaki, Atsuro Miyata, Takashi Kurihara. Spinal astrocyte-neuron lactate shuttle contributes to the pituitary adenylate cyclase-activating polypeptide/PAC1 receptor-induced nociceptive behaviors in mice. Biomolecules. 2022
Yuki Kambe, Trung Thanh Nguyen, Toshiharu Yasaka, Thu Thi Nguyen, Yoshimune Sameshima, Kohei Hashiguchi, Norihito Shintani, Hitoshi Hashimoto, Takashi Kurihara, Atsuro Miyata. The pivotal role of neuropeptide crosstalk from ventromedial-PACAP to dorsomedial-galanin in the appetite regulation in the mouse hypothalamus. Molecular Neurobiology. 2022

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MISC (48)：

神戸悠輝. 状態依存的摂食調節ペプチドPACAP. メディカル・サイエンス・ダイジェスト. 2022. 48. 4. 206-208
神戸悠輝. [公益信託児玉祈念基礎医学研究助成基金優秀論文賞」を受賞して. 鹿児島大学医学部医師会報. 2021. 41. 88-90
Ayako Miura, Yuki Kambe, Kazuhiko Inoue, Takashi Kurihara, Atsuro Miyata. SP1 is involved in not only positive but also negative expression of PAC1 gene. JOURNAL OF MOLECULAR NEUROSCIENCE. 2012. 48. S142-S142
Yuki Kambe, Kazuhiko Inoue, Takashi Kurihara, Atsuro Miyata. Involvement of mitochondria in PACAP-PAC1 dependent neurite outgrowth. JOURNAL OF MOLECULAR NEUROSCIENCE. 2012. 48. S147-S147
Rina Takenouchi, Kazuhiko Inoue, Yuki Kambe, Takashi Kurihara, Atsuro Miyata. Apoptosis of macropahges by N-arachidonoyl glycine is mediated by GPR18. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 212P-212P

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Patents (1)：

Work history (2)：

2018/05 - 現在 Kagoshima University Graduate School of Medical and Dental Sciences
2010 - 2018/04 Kagoshima University

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