Sato Yusuke

サトウユウスケ | Sato Yusuke

Affiliation and department：
Homepage URL (1)： https://kaken.nii.ac.jp/d/r/10735624.ja.html

Research field (3)： Biomaterials , Pharmaceuticals - analytical and physicochemistry , Clinical pharmacy

Research keywords (7)： mRNA , 脂質分子デザイン , ゲノム編集 , がん治療 , siRNA , 肝疾患 , 脂質ナノ粒子

Research theme for competitive and other funds (12)：

2023 - 2028 Activated mRNA delivery system based on core-shell structured LNP with smart polymers
2022 - 2024 Strategic creation of polymer-lipid hybrid nanoparticles for tissue-selective nucleic acid delivery
2019 - 2023 Innovative gene/nucleic acid delivery system based on optimized intracellular trafficking steps
2019 - 2022 Identification of novel therapeutic target for liver fibrosis and elucidation of the mechanism
2018 - 2020 novel cancer treatment by highly permeable small-sized siRNA-loaded lipid nanoparticles

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Papers (97)：

Masatoshi Maeki, Shuya Uno, Kaisei Sugiura, Yusuke Sato, Yoichiro Fujioka, Akihiko Ishida, Yusuke Ohba, Hideyoshi Harashima, Manabu Tokeshi. Development of Polymer-Lipid Hybrid Nanoparticles for Large-Sized Plasmid DNA Transfection. ACS applied materials & interfaces. 2024. 16. 2. 2110-2119
Mahmoud A. Younis, Yusuke Sato, Yaser H.A. Elewa, Hideyoshi Harashima. Reprogramming activated hepatic stellate cells by siRNA-loaded nanocarriers reverses liver fibrosis in mice. Journal of Controlled Release. 2023. 361. 592-603
Mahmoud M. Abd Elwakil, Ryota Suzuki, Alaa M. Khalifa, Rania M. Elshami, Takuya Isono, Yaser H.A. Elewa, Yusuke Sato, Takashi Nakamura, Toshifumi Satoh, Hideyoshi Harashima. Harnessing Topology and Stereochemistry of Glycidylamine-Derived Lipid Nanoparticles for in Vivo mRNA Delivery to Immune Cells in Spleen and Their Application for Cancer Vaccination. Advanced Functional Materials. 2023
Takashi Nakamura, Taisei Nakade, Yusuke Sato, Hideyoshi Harashima. Delivering mRNA to a human NK cell line, NK-92 cells, by lipid nanoparticles. International journal of pharmaceutics. 2023. 636. 122810-122810
Masatoshi Maeki, Yuto Okada, Shuya Uno, Kaisei Sugiura, Yuichi Suzuki, Kento Okuda, Yusuke Sato, Masao Ando, Hiroyuki Yamazaki, Masaki Takeuchi, et al. Mass production system for RNA-loaded lipid nanoparticles using piling up microfluidic devices. Applied Materials Today. 2023

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MISC (34)：

宇野秀哉, 真栄城正寿, 真栄城正寿, 真栄城正寿, 佐藤悠介, 石田晃彦, 日比野光恵, 谷博文, 原島秀吉, 渡慶次学. ポリカチオン/DNA複合体搭載脂質ナノ粒子による効率的な長鎖DNAトランスフェクション. 化学系学協会北海道支部冬季研究発表会(Web). 2023. 2023
岡田悠斗, 真栄城正寿, 真栄城正寿, 佐藤悠介, 石田晃彦, 谷博文, 原島秀吉, 渡慶次学. 薬剤送達ナノ粒子作製用ガラス製マイクロ流体システムの開発. 化学系学協会北海道支部冬季研究発表会(Web). 2022. 2022
杉浦魁星, 真栄城正寿, 真栄城正寿, 佐藤悠介, 石田晃彦, 谷博文, 原島秀吉, 渡慶次学. 蛍光ナノダイヤモンド搭載セラノスティクス用脂質ナノ粒子の作製. 化学とマイクロ・ナノシステム学会研究会講演要旨集(CD-ROM). 2022. 45th
宇野秀哉, 真栄城正寿, 真栄城正寿, 佐藤悠介, 石田晃彦, 原島秀吉, 渡慶次学. マイクロ流体デバイスを用いた長鎖プラスミドDNA搭載ナノ粒子の作製. 化学とマイクロ・ナノシステム学会研究会講演要旨集(CD-ROM). 2022. 46th
宇野秀哉, 真栄城正寿, 真栄城正寿, 佐藤悠介, 石田晃彦, 谷博文, 原島秀吉, 渡慶次学. マイクロ流体デバイスを用いたプラスミドDNA搭載脂質ナノ粒子の作製. 化学とマイクロ・ナノシステム学会研究会講演要旨集. 2021. 43rd

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Education (3)：

2011 - 2014 Hokkaido University Graduate School of Life Science
2009 - 2011 Hokkaido University Graduate School of Life Science
2005 - 2009 Hokkaido University Faculty of Pharmaceutical Sciences

Professional career (1)：

博士(生命科学) (北海道大学)

Work history (3)：

2016/04 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences
2014/04 - 2016/03 Hokkaido University Faculty of Pharmaceutical Sciences
2011/04 - 2014/03 日本学術振興会特別研究員(DC1)

Awards (3)：

2021/03 - The Pharmaceutical Society of Japan The Pharmaceutical Society of Japan Award for Young Scientists 2021
2016/02 - 北海道大学平成27年度北海道大学研究総長賞奨励賞
2013/07 - 日本DDS学会第29回日本DDS学会学術集会優秀発表賞

Association Membership(s) (4)：

THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN , THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM , 日本核酸医薬学会 , THE PHARMACEUTICAL SOCIETY OF JAPAN

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