Saito Takamune T

サイトウタカムネ | Saito Takamune T

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://takamunetsaito.wixsite.com/saito-lab

Research field (7)： Genetics , Molecular biology , Cell biology , Genomics , Evolutionary biology , Developmental biology , Tumor biology

Research keywords (18)： meiosis , meiotic recombination , Crossover control , Holliday junction , Holliday junction resolvase , structure specific endonuclease , Homologous recombination , Genomic instability , Progeroid syndromes , Bloom syndrome , Xeroderma pigmentosum , Fanconi anemia , DNA repair , Chromosome dynamics , Genomic integrity , mitosis , RNAi , P granule

Research theme for competitive and other funds (8)：

2023 - 2026 Regulatory mechanisms of multinuclease complex
2019 - 2022 Novel machinery of maintenance of genomic integrity by multinuclease complexes
2015 - 2017 Tissue-specific maintenance of genomic integrity by multinuclease complexes
2015 - 2017 Maintenance of genomic integrity regulated by ubiquitination of multinuclease complexes
2014 - 多重ヌクレエース複合体による組織別ゲノム統合性維持機構

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Papers (22)：

Takamune T. Saito, Koki Yamamoto, Hirohito Minami, Taiki Tsujiue. Caenorhabditis elegans brc-1 mutation increases the number of COSA-1 foci in him-8 and zim-2 mutants. microPublication Biology. 2024. 10.17912/micropub.biology.001077
Marina Martinez-Garcia, Pedro Robles Naharro, Marnie W. Skinner, Kerstin A. Baran, Laura I. Lascarez-Lagunas, Saravanapriah Nadarajan, Nara Shin, Carlos G. Silva-García, Takamune T. Saito, Sara Beese-Sims, et al. GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans. PLOS Genetics. 2023. 19. 2. e1010666-e1010666
Saravanapriah Nadarajan, Elisabeth Altendorfer, Takamune T. Saito, Marina Martinez-Garcia, Monica P. Colaiácovo. HIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis. Proceedings of the National Academy of Sciences. 2021. 118. 17. e2016363118-e2016363118
Simon Yuan Wang, Hui Mao, Hiroki Shibuya, Satoru Uzawa, Zach Klapholz O'Brown, Sage Wesenberg, Nara Shin, Takamune T Saito, Jinmin Gao, Barbara J Meyer, et al. The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline. PLoS genetics. 2019. 15. 7. e1008252
Li Q, Saito TT, Martinez-Garcia M, Deshong AJ, Nadarajan S, Lawrence KS, Checchi PM, Colaiacovo MP, Engebrecht J. The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans. PLoS Genetics. 2018. 14. 11. e1007701

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MISC (14)：

齋藤貴宗. 相同染色体間のギャップ形成が多様性を生む?. 実験医学. 2022. 40. 8. 1276-1277
山本航暉, 南寛仁, 齋藤貴宗. 線虫の染色体対合異常による新規な交差形成制御機構. 日本遺伝学会大会プログラム・予稿集. 2022. 94th (CD-ROM)
南寛仁, 齋藤貴宗. Switching of autosomal crossover formations by unpaired sex chromosomes in C. elegans oocytes. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
齋藤貴宗, 齋藤貴宗, COLAIACOVO Monica, 千葉奈津子. 多重ヌクレエース複合体によるゲノム安定性の維持. 日本分子生物学会年会プログラム・要旨集(Web). 2014. 37th
斉藤貴宗, LIU Doris, KIM Hyun-Min, MEYER Katherine, COLAIACOVO Monica. 構造特異的エンドヌクレエースによる減数分裂期交差型組換えのメカニズム. 日本分子生物学会年会プログラム・要旨集(Web). 2013. 36th

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Lectures and oral presentations (102)：

Crossover suppression in the center of chromosomes by C. elegans SLX-1
(The Genetics Society of Japan 96th Annual Meeting 2024)
Interchromosomal effect in the C. elegans meiotic recombination
(The Genetics Society of Japan 96th Annual Meeting 2024)
Analysis of the UBZ4 domain of the structure-specific nuclease HIM-18
(Kansai Worm Meeting 2024)
Roles of structure specific endonucleases in larval development and meiosis
(Kansai Worm Meeting 2023)
Relationship between unpaired chromosomes and crossover formation
(Kansai Aera Worm Meeting 2023)

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Education (3)：

2003 - 2006 Osaka University Graduate School of Science Doctor Courses at the Department of Biological Sciences
2001 - 2003 Osaka University Graduate School of Science Master Courses at the Department of Biological Sciences
1997 - 2001 Kindai University Faculty of Biology-Oriented Science and Technology Department of Genetic Engineering

Professional career (1)：

Ph.D. (Osaka University)

Work history (9)：

2024/04 - 現在 Kindai University Faculty of Biology-Oriented Science and Technology Department of Genetic Engineering Associate Professor
2018/04 - 2024/03 Kindai University Faculty of Biology-Oriented Science and Technology, Department of Genetic Engineering Lecturer
2015/06 - 2018/03 Harvard Medical School Department of Genetics Research Associate
2015/04 - 2016/03 Kindai University Institute of Advanced Technology Researcher
2014/08 - 2015/03 Tohoku University Institute of Development, Aging and Cancer Research Assistant Professor

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Committee career (2)：

2021/05 - 現在 Frontiers in Physiology, Invertebrate Physiology Review Editor
2012/04 - 現在 ISRN (International Scholarly Research Network) Genetics Editor

Awards (7)：

2013/12 - The Molecular Biology Society of Japan The invitation plan for postdoctoral fellows from overseas
2011/05 - Genetics Society of America DeLill Nasser Awards
2010/09 - Harvard Medical School Postdoctoral Travel Awards
2007/04 - Japan Society for the Promotion of Science Postdoctral Fellowship for Research Abroad
2006/04 - Japan Society for the Promotion of Science Research Fellowship for Young Scientists PD (change status from DC2)

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Association Membership(s) (3)：

The Genetics Society of Japan , Genetics Society of America , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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